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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2―activating mutations

Nature (London), 2012-12, Vol.492 (7427), p.108-112

2012

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Yangqing Chenfei formula (养清尘肺方) alleviates crystalline silica induced pulmonary inflammation and fibrosis by suppressing macrophage polarization

Journal of traditional Chinese medicine, 2023-12, Vol.43 (6), p.1126-1139

2023

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Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization

Chinese medicine, 2023-06, Vol.18 (1), p.79-79, Article 79

2023

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Synthesis of (±)- and (+)-perovskone

Tetrahedron, 2011-12, Vol.67 (52), p.10129-10146

2011

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Electronically Engineering Water Resistance in Methane Combustion with an Atomically Dispersed Tungsten on PdO Catalyst

Angewandte Chemie International Edition, 2022-07, Vol.61 (27), p.e202201655-n/a

International ed. in English, 2022

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Diels-Alder reactions of 12-hydroxy-9(10®20)-5aH-abeo-abieta-1(10),8(9),12(13)-triene-11,14-dione

Molecules, 2013-06, Vol.18 (6), p.6969-6989

2013

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Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia

Blood, 2013-11, Vol.122 (21), p.3964-3964

2013

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A simple fluorescent probe for glutathione detection and its bioimaging application in living cells

Microchemical journal, 2021-07, Vol.166, p.106135, Article 106135

2021

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Regulating catalytic stability of PtSnM/CeO2 (M = Mn, W, Nb) catalysts via the closely coupled multi-active sites to promote multicomponent VOCs oxidation

Chemical engineering journal (Lausanne, Switzerland : 1996), 2023-09, Vol.471, p.144456, Article 144456

2023

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Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents

Journal of medicinal chemistry, 2008-10, Vol.51 (19), p.6055-6066

2008

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A General Dual-Metal Nanocrystal Dissociation Strategy to Generate Robust High-Temperature-Stable Alumina-Supported Single-Atom Catalysts

Journal of the American Chemical Society, 2023-07, Vol.145 (29), p.15869-15878

2023

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Synthesis and Pharmacological Evaluation of 3-(3,4-Dichlorophenyl)-1-indanamine Derivatives as Nonselective Ligands for Biogenic Amine Transporters

Journal of medicinal chemistry, 2004-05, Vol.47 (10), p.2624-2634

2004

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A highly water-soluble rhodol-based fluorescent probe for the organic-solvent independent sensing of biological hypochlorous acid

Dyes and pigments, 2022-08, Vol.204, p.110435, Article 110435

2022

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In vivo precision imaging of vicinal-dithiol-containing proteins by a FRET molecular probe sensitive to protein environment

Chinese chemical letters, 2023-12, Vol.34 (12), p.108329, Article 108329

2023

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A spiropyran with low pKa for tracking DNA G-quadruplexes and revealing the dissipation of ΔΨm with senescence using an in-situ switching strategy

Sensors and actuators. B, Chemical, 2022-05, Vol.359, p.131618, Article 131618

2022

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Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14391-14408

2022

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Design and synthesis of potent and selective 1,3,4-trisubstituted-2-oxopiperazine based melanocortin-4 receptor agonists

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (17), p.4668-4673

2006

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Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells

Bioorganic & medicinal chemistry letters, 2023-08, Vol.92, p.129385-129385, Article 129385

2023

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An efficient and practical synthesis of 2,4-substituted pyrido[4,3-d]pyrimidin-5(6H)-ones

Tetrahedron letters, 2019-12, Vol.60 (49), p.151312, Article 151312

2019

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Digoxin alleviates pulmonary fibrosis by regulating phosphatidylinositol-3-kinase/Akt signaling through inhibiting the activation of fibroblast: an in vivo and in vitro experiment

Zhonghua wei zhong bing ji jiu yi xue, 2022-11, Vol.34 (11), p.1161

2022

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Probes for Narcotic Receptor-Mediated Phenomena. 33. Construction of a Strained trans-5,6-Ring System by Displacement of a Nitro-Activated Aromatic Fluorine. Synthesis of the Penultimate Oxide-Bridged Phenylmorphans

Journal of organic chemistry, 2004-08, Vol.69 (16), p.5322-5327

2004

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Design, Synthesis, and Evaluation of Proline and Pyrrolidine Based Melanocortin Receptor Agonists. A Conformationally Restricted Dipeptide Mimic Approach

Journal of medicinal chemistry, 2006-07, Vol.49 (15), p.4745-4761

2006

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Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c‑MYC Protein Levels in Cells

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.16056-16087

2021

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Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2

ACS medicinal chemistry letters, 2012-12, Vol.3 (12), p.1091-1096

2012

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Synthesis of Tic-d-Phe Ψ[CH2–CH2] isostere and its use in the development of melanocortin receptor agonists

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1721-1725

2006

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2―activating mutations

Yangqing Chenfei formula (养清尘肺方) alleviates crystalline silica induced pulmonary inflammation and fibrosis by suppressing macrophage polarization

Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization

Synthesis of (±)- and (+)-perovskone

Electronically Engineering Water Resistance in Methane Combustion with an Atomically Dispersed Tungsten on PdO Catalyst

Diels-Alder reactions of 12-hydroxy-9(10®20)-5aH-abeo-abieta-1(10),8(9),12(13)-triene-11,14-dione

Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia

A simple fluorescent probe for glutathione detection and its bioimaging application in living cells

Regulating catalytic stability of PtSnM/CeO2 (M = Mn, W, Nb) catalysts via the closely coupled multi-active sites to promote multicomponent VOCs oxidation

Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents

A General Dual-Metal Nanocrystal Dissociation Strategy to Generate Robust High-Temperature-Stable Alumina-Supported Single-Atom Catalysts

Synthesis and Pharmacological Evaluation of 3-(3,4-Dichlorophenyl)-1-indanamine Derivatives as Nonselective Ligands for Biogenic Amine Transporters

A highly water-soluble rhodol-based fluorescent probe for the organic-solvent independent sensing of biological hypochlorous acid

In vivo precision imaging of vicinal-dithiol-containing proteins by a FRET molecular probe sensitive to protein environment

A spiropyran with low pKa for tracking DNA G-quadruplexes and revealing the dissipation of ΔΨm with senescence using an in-situ switching strategy

Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening

Design and synthesis of potent and selective 1,3,4-trisubstituted-2-oxopiperazine based melanocortin-4 receptor agonists

Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells

An efficient and practical synthesis of 2,4-substituted pyrido[4,3-d]pyrimidin-5(6H)-ones

Digoxin alleviates pulmonary fibrosis by regulating phosphatidylinositol-3-kinase/Akt signaling through inhibiting the activation of fibroblast: an in vivo and in vitro experiment

Probes for Narcotic Receptor-Mediated Phenomena. 33. Construction of a Strained trans-5,6-Ring System by Displacement of a Nitro-Activated Aromatic Fluorine. Synthesis of the Penultimate Oxide-Bridged Phenylmorphans

Design, Synthesis, and Evaluation of Proline and Pyrrolidine Based Melanocortin Receptor Agonists. A Conformationally Restricted Dipeptide Mimic Approach

Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c‑MYC Protein Levels in Cells

Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2

Synthesis of Tic-d-Phe Ψ[CH2–CH2] isostere and its use in the development of melanocortin receptor agonists

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