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NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway

The Journal of biological chemistry, 2002-12, Vol.277 (50), p.48043-48050

2002

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Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

Nature cell biology, 2002-02, Vol.4 (2), p.95-105

2002

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Selective, Reversible Caspase-3 Inhibitor Is Neuroprotective and Reveals Distinct Pathways of Cell Death after Neonatal Hypoxic-ischemic Brain Injury

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.30128-30136

2002

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An Enhanced Immune Response in Mice Lacking the Transcription Factor NFAT1

Science (American Association for the Advancement of Science), 1996-05, Vol.272 (5263), p.892-895

1996

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Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics

The Journal of experimental medicine, 2004-01, Vol.199 (2), p.199-207

2004

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Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis

The EMBO journal, 1999-04, Vol.18 (8), p.2049-2056

1999

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Heat-shock proteins as death determinants

Nature cell biology, 2000-09, Vol.2 (9), p.E163-E165

2000

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Identification and characterization of Ref‐1, a nuclear protein that facilitates AP‐1 DNA‐binding activity

The EMBO journal, 1992-02, Vol.11 (2), p.653-665

1992

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The Redox/DNA Repair Protein, Ref-1, is Essential for Early Embryonic Development in Mice

Proceedings of the National Academy of Sciences - PNAS, 1996-08, Vol.93 (17), p.8919-8923

1996

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Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors

Cell death and differentiation, 2004-04, Vol.11 (4), p.439-447

2004

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Redox activation of Fos‐Jun DNA binding activity is mediated by a DNA repair enzyme

The EMBO journal, 1992-09, Vol.11 (9), p.3323-3335

1992

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The Redox and DNA-Repair Activities of Ref-1 are Encoded by Nonoverlapping Domains

Proceedings of the National Academy of Sciences - PNAS, 1994-01, Vol.91 (1), p.23-27

1994

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Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia

Molecular and Cellular Biology, 1994-09, Vol.14 (9), p.5997-6003

1994

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Gob-5 Is Not Essential for Mucus Overproduction in Preclinical Murine Models of Allergic Asthma

American journal of respiratory cell and molecular biology, 2005-09, Vol.33 (3), p.303-314

2005

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Neuroprotective effects of M826, a reversible caspase‐3 inhibitor, in the rat malonate model of Huntington's disease

British journal of pharmacology, 2004-02, Vol.141 (4), p.689-697

2004

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Apical membrane insertion of CFTR is increased by protein kinase C activation

The FASEB journal, 2006-03, Vol.20 (4), p.A797-A797

2006

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Redox regulation of AP-1: a link between transcription factor signaling and DNA repair

Advances in experimental medicine and biology, 1996, Vol.387, p.69

1996

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Th2 driven anion conductance in airway epithelium is lost in the mCLCA3 knockout mouse

The FASEB journal, 2006-03, Vol.20 (4), p.A348-A348

2006

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Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay

Analytical biochemistry, 2006-03, Vol.350 (1), p.32-40

2006

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Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1671-1674

2007

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Escape from redox regulation enhances the transforming activity of Fos

Oncogene, 1993-03, Vol.8 (3), p.695-701

1993

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Nicotinyl aspartyl ketones as inhibitors of caspase-3

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (13), p.2137-2140

2003

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Lipophilic versus hydrogen-bonding effect in P 3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (17), p.3886-3890

2005

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Solid phase synthesis of selective caspase-3 peptide inhibitors

Bioorganic & medicinal chemistry, 2004-03, Vol.12 (5), p.845-851

2004

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Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (17), p.3886-3890

2005

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NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

Selective, Reversible Caspase-3 Inhibitor Is Neuroprotective and Reveals Distinct Pathways of Cell Death after Neonatal Hypoxic-ischemic Brain Injury

An Enhanced Immune Response in Mice Lacking the Transcription Factor NFAT1

Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics

Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis

Heat-shock proteins as death determinants

Identification and characterization of Ref‐1, a nuclear protein that facilitates AP‐1 DNA‐binding activity

The Redox/DNA Repair Protein, Ref-1, is Essential for Early Embryonic Development in Mice

Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors

Redox activation of Fos‐Jun DNA binding activity is mediated by a DNA repair enzyme

The Redox and DNA-Repair Activities of Ref-1 are Encoded by Nonoverlapping Domains

Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia

Gob-5 Is Not Essential for Mucus Overproduction in Preclinical Murine Models of Allergic Asthma

Neuroprotective effects of M826, a reversible caspase‐3 inhibitor, in the rat malonate model of Huntington's disease

Apical membrane insertion of CFTR is increased by protein kinase C activation

Redox regulation of AP-1: a link between transcription factor signaling and DNA repair

Th2 driven anion conductance in airway epithelium is lost in the mCLCA3 knockout mouse

Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay

Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones

Escape from redox regulation enhances the transforming activity of Fos

Nicotinyl aspartyl ketones as inhibitors of caspase-3

Lipophilic versus hydrogen-bonding effect in P 3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

Solid phase synthesis of selective caspase-3 peptide inhibitors

Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

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