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Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonists as Novel Analgesics for Neuropathic Pain: Comparative Pharmacokinetics, Radioligand Binding, and Efficacy in Rats

Pain medicine (Malden, Mass.), 2013-05, Vol.14 (5), p.692-705

2013

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Optimization and pharmacological characterization of a refined cisplatin-induced rat model of peripheral neuropathic pain

Behavioural pharmacology, 2014-12, Vol.25 (8), p.732-740

2014

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Analgesic Efficacy and Mode of Action of a Selective Small Molecule Angiotensin II Type 2 Receptor Antagonist in a Rat Model of Prostate Cancer‐Induced Bone Pain

Pain medicine (Malden, Mass.), 2014-01, Vol.15 (1), p.93-110

2014

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Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation

PloS one, 2012-08, Vol.7 (8), p.e41909

2012

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Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 Sensitization

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19540-19550

2008

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The μ Opioid Agonist Morphine Modulates Potentiation of Capsaicin-Evoked TRPV1 Responses through a Cyclic AMP-Dependent Protein Kinase a Pathway

Molecular pain, 2006-07, Vol.2 (1), p.22-22

2006

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Caveolin Interacts with the Angiotensin II Type 1 Receptor during Exocytic Transport but Not at the Plasma Membrane

The Journal of biological chemistry, 2003-06, Vol.278 (26), p.23738-23746

2003

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Longitudinal Study of Painful Diabetic Neuropathy in the Zucker Diabetic Fatty Rat Model of Type 2 Diabetes: Impaired Basal G-Protein Activity Appears to Underpin Marked Morphine Hyposensitivity at 6 Months

Pain medicine (Malden, Mass.), 2011-03, Vol.12 (3), p.437-450

2011

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Synthesis and Biological Evaluation of an Orally Active Glycosylated Endomorphin-1

Journal of medicinal chemistry, 2012-06, Vol.55 (12), p.5859-5867

2012

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SEX DIFFERENCES IN THE PHARMACOKINETICS, OXIDATIVE METABOLISM AND ORAL BIOAVAILABILITY OF OXYCODONE IN THE SPRAGUE-DAWLEY RAT

Clinical and experimental pharmacology & physiology, 2008-03, Vol.35 (3), p.295-302

2008

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Nitric oxide modulates μ‐opioid receptor function in vitro

Clinical and experimental pharmacology & physiology, 2019-07, Vol.46 (7), p.676-685

2019

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A Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonist Produces Analgesia in a Rat Model of Neuropathic Pain by Inhibition of p38 Mitogen‐Activated Protein Kinase (MAPK) and p44/p42 MAPK Activation in the Dorsal Root Ganglia

Pain medicine (Malden, Mass.), 2013-10, Vol.14 (10), p.1557-1568

2013

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Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioral, pharmacological, radiological, histological and immunohistochemical methods

Pharmacology, biochemistry and behavior, 2013-05, Vol.106, p.33-46

2013

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Topical Application of a Novel Oxycodone Gel Formulation (Tocopheryl Phosphate Mixture) in a Rat Model of Peripheral Inflammatory Pain Produces Localized Pain Relief Without Significant Systemic Exposure

Journal of pharmaceutical sciences, 2015-07, Vol.104 (7), p.2388-2396

2015

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Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol

European journal of pain, 2008-05, Vol.12 (4), p.441-454

2008

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The furoxan nitric oxide donor, PRG150, evokes dose-dependent analgesia in a rat model of painful diabetic neuropathy

Clinical and experimental pharmacology & physiology, 2015-09, Vol.42 (9), p.921-929

2015

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Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation

Bioorganic & medicinal chemistry, 2013-04, Vol.21 (7), p.1898-1904

2013

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Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy

Behavioural pharmacology, 2014-04, Vol.25 (2), p.137-146

2014

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Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity

Bioorganic & medicinal chemistry, 2014-04, Vol.22 (7), p.2208-2219

2014

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Insulin Implants Prevent the Temporal Development of Mechanical Allodynia and Opioid Hyposensitivity for 24-Wks in Streptozotocin (STZ)-Diabetic Wistar Rats

Pain medicine (Malden, Mass.), 2011-05, Vol.12 (5), p.782-793

2011

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The furoxan nitric oxide donor, PRG 150, evokes dose‐dependent analgesia in a rat model of painful diabetic neuropathy

Clinical and experimental pharmacology & physiology, 2015-09, Vol.42 (9), p.921-929

2015

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Longitudinal Study of Painful Diabetic Neuropathy in the Zucker Diabetic Fatty Rat Model of Type 2 Diabetes: Impaired Basal GaProtein Activity Appears to Underpin Marked Morphine Hyposensitivity at 6 Months

Pain medicine (Malden, Mass.), 2011-03, Vol.12 (3), p.437-450

2011

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Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 SensitizationS

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19540-19550

2008

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The size and Census coverage of the U.S. homeless population

Journal of urban economics, 2023-07, Vol.136, p.103559, Article 103559

2023

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Validation of European System for Cardiac Operative Risk Evaluation (EuroSCORE) in North American cardiac surgery

European journal of cardio-thoracic surgery, 2002-07, Vol.22 (1), p.101-105

2002

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Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonists as Novel Analgesics for Neuropathic Pain: Comparative Pharmacokinetics, Radioligand Binding, and Efficacy in Rats

Optimization and pharmacological characterization of a refined cisplatin-induced rat model of peripheral neuropathic pain

Analgesic Efficacy and Mode of Action of a Selective Small Molecule Angiotensin II Type 2 Receptor Antagonist in a Rat Model of Prostate Cancer‐Induced Bone Pain

Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation

Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 Sensitization

The μ Opioid Agonist Morphine Modulates Potentiation of Capsaicin-Evoked TRPV1 Responses through a Cyclic AMP-Dependent Protein Kinase a Pathway

Caveolin Interacts with the Angiotensin II Type 1 Receptor during Exocytic Transport but Not at the Plasma Membrane

Longitudinal Study of Painful Diabetic Neuropathy in the Zucker Diabetic Fatty Rat Model of Type 2 Diabetes: Impaired Basal G-Protein Activity Appears to Underpin Marked Morphine Hyposensitivity at 6 Months

Synthesis and Biological Evaluation of an Orally Active Glycosylated Endomorphin-1

SEX DIFFERENCES IN THE PHARMACOKINETICS, OXIDATIVE METABOLISM AND ORAL BIOAVAILABILITY OF OXYCODONE IN THE SPRAGUE-DAWLEY RAT

Nitric oxide modulates μ‐opioid receptor function in vitro

A Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonist Produces Analgesia in a Rat Model of Neuropathic Pain by Inhibition of p38 Mitogen‐Activated Protein Kinase (MAPK) and p44/p42 MAPK Activation in the Dorsal Root Ganglia

Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioral, pharmacological, radiological, histological and immunohistochemical methods

Topical Application of a Novel Oxycodone Gel Formulation (Tocopheryl Phosphate Mixture) in a Rat Model of Peripheral Inflammatory Pain Produces Localized Pain Relief Without Significant Systemic Exposure

Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol

The furoxan nitric oxide donor, PRG150, evokes dose-dependent analgesia in a rat model of painful diabetic neuropathy

Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation

Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy

Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity

Insulin Implants Prevent the Temporal Development of Mechanical Allodynia and Opioid Hyposensitivity for 24-Wks in Streptozotocin (STZ)-Diabetic Wistar Rats

The furoxan nitric oxide donor, PRG 150, evokes dose‐dependent analgesia in a rat model of painful diabetic neuropathy

Longitudinal Study of Painful Diabetic Neuropathy in the Zucker Diabetic Fatty Rat Model of Type 2 Diabetes: Impaired Basal GaProtein Activity Appears to Underpin Marked Morphine Hyposensitivity at 6 Months

Rapid, Opioid-sensitive Mechanisms Involved in Transient Receptor Potential Vanilloid 1 SensitizationS

The size and Census coverage of the U.S. homeless population

Validation of European System for Cardiac Operative Risk Evaluation (EuroSCORE) in North American cardiac surgery

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