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Nitrite lowers the oxygen cost of ATP supply in cultured skeletal muscle cells by stimulating the rate of glycolytic ATP synthesis

PloS one, 2022-08, Vol.17 (8), p.e0266905-e0266905

2022

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Patients' and clinicians' perspectives towards primary care consultations for shoulder pain: qualitative findings from the Prognostic and Diagnostic Assessment of the Shoulder (PANDA-S) programme

BMC musculoskeletal disorders, 2023-01, Vol.24 (1), p.1-1, Article 1

2023

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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling

PloS one, 2012-01, Vol.7 (1), p.e28568

2012

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Five-year survival after first-ever stroke and related prognostic factors in the Perth Community Stroke Study

Stroke (1970), 2000-09, Vol.31 (9), p.2080-2086

2000

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Design of Potent and Selective Hybrid Inhibitors of the Mitotic Kinase Nek2: Structure–Activity Relationship, Structural Biology, and Cellular Activity

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3228-3241

2012

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Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange

The EMBO journal, 2006-07, Vol.25 (13), p.3179-3190

2006

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Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B through Structure-Based Design

Journal of medicinal chemistry, 2007-05, Vol.50 (10), p.2289-2292

2007

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Identification of 4-(4-Aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as Selective Inhibitors of Protein Kinase B through Fragment Elaboration

Journal of medicinal chemistry, 2008-04, Vol.51 (7), p.2147-2157

2008

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Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization

Journal of medicinal chemistry, 2010-11, Vol.53 (21), p.7682-7698

2010

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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

Molecular cancer therapeutics, 2005-10, Vol.4 (10), p.1521-1532

2005

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iSoBAR — a concept and handover checklist: the National Clinical Handover Initiative

Medical journal of Australia, 2009-06, Vol.190 (S11), p.S152-S156

2009

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Long-term risk of first recurrent stroke in the perth community stroke study

Stroke (1970), 1998-12, Vol.29 (12), p.2491-2500

1998

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CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs

Clinical cancer research, 2012-10, Vol.18 (20), p.5650-5661

2012

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Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1626-1639

2011

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Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.2239-2249

2010

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Admission inflammatory markers and isolation of a causative organism in patients with spontaneous spinal infection

Annals of the Royal College of Surgeons of England, 2013-11, Vol.95 (8), p.604-608

2013

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The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3338-3343

2005

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Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2

Bioorganic & medicinal chemistry, 2010-01, Vol.18 (2), p.707-718

2010

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Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening

Journal of medicinal chemistry, 2009-08, Vol.52 (15), p.4810-4819

2009

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The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106

Molecular cancer therapeutics, 2010-01, Vol.9 (1), p.89-100

2010

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Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2

PloS one, 2013-06, Vol.8 (6), p.e65689-e65689

2013

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A population-based assessment of the impact and burden of caregiving for long-term stroke survivors

Stroke (1970), 1995-05, Vol.26 (5), p.843-849

1995

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Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs)

Bioorganic & medicinal chemistry, 2009-01, Vol.17 (2), p.467-474

2009

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Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2

Journal of medicinal chemistry, 2011-01, Vol.54 (2), p.580-590

2011

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Nitrite lowers the oxygen cost of ATP supply in cultured skeletal muscle cells by stimulating the rate of glycolytic ATP synthesis

Patients' and clinicians' perspectives towards primary care consultations for shoulder pain: qualitative findings from the Prognostic and Diagnostic Assessment of the Shoulder (PANDA-S) programme

Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling

Five-year survival after first-ever stroke and related prognostic factors in the Perth Community Stroke Study

Design of Potent and Selective Hybrid Inhibitors of the Mitotic Kinase Nek2: Structure–Activity Relationship, Structural Biology, and Cellular Activity

Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange

Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B through Structure-Based Design

Identification of 4-(4-Aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as Selective Inhibitors of Protein Kinase B through Fragment Elaboration

Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization

Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

iSoBAR — a concept and handover checklist: the National Clinical Handover Initiative

Long-term risk of first recurrent stroke in the perth community stroke study

CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs

Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship

Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)

Admission inflammatory markers and isolation of a causative organism in patients with spontaneous spinal infection

The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2

Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)‑5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)

Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening

The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106

Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2

A population-based assessment of the impact and burden of caregiving for long-term stroke survivors

Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs)

Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2

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