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Editorial: Managing cancer metastasis by tackling anticancer drug resistance

Frontiers in pharmacology, 2024-06, Vol.15, p.1432248

2024

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Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth

Clinical cancer research, 2013-10, Vol.19 (20), p.5613-5625

2013

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MYCN mRNA degradation and cancer suppression by a selective small-molecule inhibitor in MYCN-amplified neuroblastoma

Frontiers in oncology, 2022-11, Vol.12, p.1058726-1058726

2022

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JW-1-283 inhibits melanoma tumor growth via stabilization of the p53 pathway

Genes & diseases, 2024-05, Vol.11 (3), p.101036-101036, Article 101036

2024

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Small molecule conjugates with selective estrogen receptor β agonism promote anti-aging benefits in metabolism and skin recovery

Acta pharmaceutica Sinica. B, 2024-05, Vol.14 (5), p.2137-2152

2024

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Design, synthesis and biological evaluation of selective survivin inhibitors

Journal of biomedical research, 2019, Vol.33 (2), p.82-100

2019

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Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation

PloS one, 2013-12, Vol.8 (12), p.e83380

2013

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A New Titanium Tetrachloride Mediated Annulation of α-Aryl-Substituted Carbonyl Compounds with Alkynes: A Simple and Highly Efficient Method for the Regioselective Synthesis of Polysubstituted Naphthalene Derivatives

Journal of organic chemistry, 2003-10, Vol.68 (20), p.7915-7917

2003

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Boron Trihalide Mediated Alkyne-Aldehyde Coupling Reactions: A Mechanistic Investigation

Journal of organic chemistry, 2008-04, Vol.73 (7), p.2668-2673

2008

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Titanium(IV) Halide Mediated Coupling of Alkoxides and Alkynes: An Efficient and Stereoselective Route to Trisubstituted (E)-Alkenyl Halides

Organic letters, 2009-06, Vol.11 (12), p.2647-2649

2009

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An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues

Cancer letters, 2024-08, Vol.598, p.217126, Article 217126

2024

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Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold

European journal of medicinal chemistry, 2023-07, Vol.255, p.115423-115423, Article 115423

2023

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Synthesis of a series of boronated unnatural cyclic amino acids as potential boron neutron capture therapy agents

Applied organometallic chemistry, 2008-09, Vol.22 (9), p.516-522

2008

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Ovarian Primary and Metastatic Tumors Suppressed by Survivin Knockout or a Novel Survivin Inhibitor

Molecular cancer therapeutics, 2019-12, Vol.18 (12), p.2233-2245

2019

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Inhibition of TRPC3 channels by a novel pyrazole compound confers antiseizure effects

Epilepsia (Copenhagen), 2022-04, Vol.63 (4), p.1003-1015

2022

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A New Halopropargylation of Alkynes Promoted by Boron Trihalides. Highly Stereo- and Regioselective Syntheses of Substituted (Z)-1-Halo-1,4-enyne Derivatives

Organic letters, 2004-10, Vol.6 (22), p.3929-3931

2004

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Discovery of N‑(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2‑c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor

Journal of medicinal chemistry, 2021-02, Vol.64 (4), p.1930-1950

2021

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Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7877-7891

2018

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Survivin Inhibitors Mitigate Chemotherapeutic Resistance in Breast Cancer Cells by Suppressing Genotoxic Nuclear Factor- κ B Activation

The Journal of pharmacology and experimental therapeutics, 2018-07, Vol.366 (1), p.184-193

2018

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Abstract 2784: JW-1-283 inhibits melanoma tumor growth via the stabilization of p53 pathway

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2784-2784

2023

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Abstract 5264: Selective toxicity of MX-106-4C, a survivin inhibitor, in P-glycoprotein-mediated multidrug resistant colon cancer

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5264-5264

2020

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Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold

European journal of medicinal chemistry, 2021-11, Vol.224, p.113719-113719, Article 113719

2021

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SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis

Cancer letters, 2023-02, Vol.555, p.216046-216046, Article 216046

2023

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A Novel Titanium Tetrahalide-Mediated Carbon−Carbon Bond-Forming Reaction: Regioselective Synthesis of Substituted (E,Z)-1,5-Dihalo-1,4-dienes

Organic letters, 2002-10, Vol.4 (20), p.3415-3417

2002

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X‑ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor

Journal of medicinal chemistry, 2021-09, Vol.64 (17), p.13072-13095

2021

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Editorial: Managing cancer metastasis by tackling anticancer drug resistance

Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth

MYCN mRNA degradation and cancer suppression by a selective small-molecule inhibitor in MYCN-amplified neuroblastoma

JW-1-283 inhibits melanoma tumor growth via stabilization of the p53 pathway

Small molecule conjugates with selective estrogen receptor β agonism promote anti-aging benefits in metabolism and skin recovery

Design, synthesis and biological evaluation of selective survivin inhibitors

Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation

A New Titanium Tetrachloride Mediated Annulation of α-Aryl-Substituted Carbonyl Compounds with Alkynes: A Simple and Highly Efficient Method for the Regioselective Synthesis of Polysubstituted Naphthalene Derivatives

Boron Trihalide Mediated Alkyne-Aldehyde Coupling Reactions: A Mechanistic Investigation

Titanium(IV) Halide Mediated Coupling of Alkoxides and Alkynes: An Efficient and Stereoselective Route to Trisubstituted (E)-Alkenyl Halides

An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues

Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold

Synthesis of a series of boronated unnatural cyclic amino acids as potential boron neutron capture therapy agents

Ovarian Primary and Metastatic Tumors Suppressed by Survivin Knockout or a Novel Survivin Inhibitor

Inhibition of TRPC3 channels by a novel pyrazole compound confers antiseizure effects

A New Halopropargylation of Alkynes Promoted by Boron Trihalides. Highly Stereo- and Regioselective Syntheses of Substituted (Z)-1-Halo-1,4-enyne Derivatives

Discovery of N‑(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2‑c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor

Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities

Survivin Inhibitors Mitigate Chemotherapeutic Resistance in Breast Cancer Cells by Suppressing Genotoxic Nuclear Factor- κ B Activation

Abstract 2784: JW-1-283 inhibits melanoma tumor growth via the stabilization of p53 pathway

Abstract 5264: Selective toxicity of MX-106-4C, a survivin inhibitor, in P-glycoprotein-mediated multidrug resistant colon cancer

Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold

SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis

A Novel Titanium Tetrahalide-Mediated Carbon−Carbon Bond-Forming Reaction: Regioselective Synthesis of Substituted (E,Z)-1,5-Dihalo-1,4-dienes

X‑ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor

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