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Urothelial tumorigenesis: a tale of divergent pathways

Nature reviews. Cancer, 2005-09, Vol.5 (9), p.713-725

Wu, Xue-Ru

2005

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Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin

Scientific reports, 2017-04, Vol.7 (1), p.45983-45983, Article 45983

2017

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XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin‐mediated Rho‐GDIβ mRNA stability

International journal of cancer, 2018-05, Vol.142 (10), p.2040-2055

2018

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Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (43), p.21727-21731

2019

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Uromodulin (Tamm–Horsfall protein): guardian of urinary and systemic homeostasis

Nephrology, dialysis, transplantation, 2020-01, Vol.35 (1), p.33-43

2020

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Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis

Nature communications, 2021-04, Vol.12 (1), p.2047-15, Article 2047

2021

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PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein

Oncogene, 2018-10, Vol.37 (43), p.5735-5748

2018

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Bladder cancers arise from distinct urothelial sub-populations

Nature cell biology, 2014-10, Vol.16 (10), p.982-991

2014

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Structural or functional defects of PTEN in urothelial cells lacking P53 drive basal/squamous-subtype muscle-invasive bladder cancer

Cancer letters, 2022-12, Vol.550, p.215924-215924, Article 215924

2022

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Three novel mononuclear 4‐vinylpyridine‐based Fe(III) complexes displaying various spin‐crossover behaviour

European journal of inorganic chemistry, 2024-03, Vol.27 (8), p.n/a

2024

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Aristolochic acid-associated urothelial cancer in Taiwan

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.8241-8246

2012

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ATG7 Promotes Bladder Cancer Invasion via Autophagy‐Mediated Increased ARHGDIB mRNA Stability

Advanced science, 2019-04, Vol.6 (8), p.1801927-n/a

2019

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Uroplakins in urothelial biology, function, and disease

Kidney international, 2009-06, Vol.75 (11), p.1153-1165

2009

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Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism

Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1666

2023

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Uromodulin-SlpA binding dictates Lactobacillus acidophilus uptake by intestinal epithelial M cells

International immunology, 2017-08, Vol.29 (8), p.357-363

2017

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MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion

Molecular therapy. Nucleic acids, 2019-06, Vol.16, p.51-62

2019

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Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel

Science translational medicine, 2019-10, Vol.11 (512)

2019

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Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer

Oncogene, 2020-02, Vol.39 (6), p.1302-1317

2020

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Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney

Journal of the American Society of Nephrology, 2018-03, Vol.29 (3), p.841-856

2018

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Role of STAT3 and FOXO1 in the Divergent Therapeutic Responses of Non-metastatic and Metastatic Bladder Cancer Cells to miR-145

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.924-935

2017

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Uromodulin in Kidney Injury: An Instigator, Bystander, or Protector?

American journal of kidney diseases, 2012-03, Vol.59 (3), p.452-461

2012

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Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia

PloS one, 2017-11, Vol.12 (11), p.e0186769-e0186769

2017

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The kidney protects against sepsis by producing systemic uromodulin

American journal of physiology. Renal physiology, 2022-08, Vol.323 (2), p.F212-F226

2022

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Decreased Tumorigenesis and Mortality from Bladder Cancer in Mice Lacking Urothelial Androgen Receptor

The American journal of pathology, 2013-05, Vol.182 (5), p.1811-1820

2013

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Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury

American journal of physiology. Renal physiology, 2013-04, Vol.304 (8), p.F1066-F1075

2013

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Urothelial tumorigenesis: a tale of divergent pathways

Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin

XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin‐mediated Rho‐GDIβ mRNA stability

Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice

Uromodulin (Tamm–Horsfall protein): guardian of urinary and systemic homeostasis

Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis

PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein

Bladder cancers arise from distinct urothelial sub-populations

Structural or functional defects of PTEN in urothelial cells lacking P53 drive basal/squamous-subtype muscle-invasive bladder cancer

Three novel mononuclear 4‐vinylpyridine‐based Fe(III) complexes displaying various spin‐crossover behaviour

Aristolochic acid-associated urothelial cancer in Taiwan

ATG7 Promotes Bladder Cancer Invasion via Autophagy‐Mediated Increased ARHGDIB mRNA Stability

Uroplakins in urothelial biology, function, and disease

Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism

Uromodulin-SlpA binding dictates Lactobacillus acidophilus uptake by intestinal epithelial M cells

MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion

Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel

Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney

Role of STAT3 and FOXO1 in the Divergent Therapeutic Responses of Non-metastatic and Metastatic Bladder Cancer Cells to miR-145

Uromodulin in Kidney Injury: An Instigator, Bystander, or Protector?

Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia

The kidney protects against sepsis by producing systemic uromodulin

Decreased Tumorigenesis and Mortality from Bladder Cancer in Mice Lacking Urothelial Androgen Receptor

Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury

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