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Research progress of the multifunctional oxidase scopolamine 6β-hydroxylase

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2024-09, Vol.40 (9), p.2786

2024

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Highly Efficient Enzymatic Synthesis of C6-Substituted Δ1‑3-Ketosteroids Enabled by Finely Tuning the Substrate Binding of 3‑Ketosteroid‑Δ1‑Dehydrogenase

ACS sustainable chemistry & engineering, 2024-08, Vol.12 (34), p.12845-12857

2024

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Asymmetric carbohydroxylation of alkenes via sequential photocatalytic oxo-alkylation and enzymatic reduction

Tetrahedron chem, 2024-08, Vol.11, p.100083, Article 100083

2024

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Manipulating Activity and Chemoselectivity of a Benzaldehyde Lyase for Efficient Synthesis of α‑Hydroxymethyl Ketones and One-Pot Enantio-Complementary Conversion to 1,2-Diols

ACS catalysis, 2024-07, Vol.14 (13), p.9687-9700

2024

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Molecular modification of cyclodextrin glucosyltransferase and its application in the synthesis of α-arbutin

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2024-06, Vol.40 (6), p.1845

2024

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Identification and structure-based engineering of a dipeptidase CpPepD from Clostridium perfringens for the synthesis of l-carnosine

Journal of biotechnology, 2024-06, Vol.389, p.86-93

2024

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Biocatalytic production of (S)-1,2,4-butanetriol from d-xylose by whole cells of engineered Escherichia coli

Molecular catalysis, 2024-06, Vol.562, p.114230, Article 114230

2024

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Engineered Imine Reductase for Asymmetric Synthesis of Dextromethorphan Key Intermediate

Organic letters, 2024-05, Vol.26 (21), p.4463-4468

2024

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Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols

JACS Au, 2024-04, Vol.4 (4), p.1356-1364

2024

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Discovery and directed evolution of C-C bond formation enzymes for the biosynthesis of β-hydroxy-α-amino acids and derivatives

Critical reviews in biotechnology, 2024-04, p.1-20

2024

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Engineering of halohydrin dehalogenases for the regio- and stereoselective synthesis of ()-4-aryl-2-oxazolidinones

Catalysis science & technology, 2024-04, Vol.14 (7), p.1967-1976

2024

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Efficient synthesis of (R)-4-methoxyamphetamine and its analogues under low ammonium concentration using engineered amine dehydrogenase

Molecular catalysis, 2024-01, Vol.553, p.113802, Article 113802

2024

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Reshaping the Substrate Binding Pocket of β-Amino Acid Dehydrogenase for the Synthesis of Aromatic β-Amino Acids

Organic letters, 2023-12, Vol.25 (47), p.8469-8473

2023

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Photoredox/Enzymatic Catalysis Enabling Redox-Neutral Decarboxylative Asymmetric C–C Coupling for Asymmetric Synthesis of Chiral 1,2-Amino Alcohols

JACS Au, 2023-11, Vol.3 (11), p.3005-3013

2023

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The function of steroid terminal monooxygenase in cholesterol or phytosterol degradation by the Mycobacterium neoaurum NRRL B-3805

Systems Microbiology and Biomanufacturing, 2023-10, Vol.3 (4), p.585-592

2023

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Semirational Engineering of a Thermostable Carbonyl Reductase for the Precision Synthesis of (2R,3R)‑2-Methyl-2-benzyl-3-hydroxycyclopentanone and Its Analogues

Journal of organic chemistry, 2023-08, Vol.88 (16), p.11905-11912

2023

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Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer

ACS catalysis, 2023-08, Vol.13 (15), p.9960-9968

2023

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Efficient enzymatic synthesis of (S)-1-(3′-bromo-2′-methoxyphenyl)ethanol, the key building block of lusutrombopag

Green synthesis and catalysis, 2023-08, Vol.4 (3), p.268-271

2023

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Stereocomplementary Synthesis of β‐Aryl Propanamines by Enzymatic Dynamic Kinetic Resolution‐Reductive Amination

European journal of organic chemistry, 2023-07, Vol.26 (28), p.n/a

2023

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Chemo-enzymatic synthesis of chiral 3-substituted tetrahydroquinolines by a sequential biocatalytic cascade and Buchwald-Hartwig cyclization

Green chemistry : an international journal and green chemistry resource : GC, 2023-06, Vol.25 (12), p.4667-4673

2023

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Structure-guided semi-rational design of an imine reductase for enantio-complementary synthesis of pyrrolidinamine

Chemical science (Cambridge), 2023-04, Vol.14 (16), p.4265-4272

2023

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Enantiodivergent Synthesis of 1‑Heteroaryl Tetrahydroisoquinolines Catalyzed by Imine Reductases

Organic letters, 2023-04, Vol.25 (14), p.2438-2443

2023

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Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4‑Aryl-2-oxazolidinones from Readily Available Epoxides

ACS catalysis, 2023-04, Vol.13 (7), p.4768-4777

2023

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Desymmetric Reductive Amination of 1,3-Cyclopentadiones to Single Stereoisomer of β‑Amino Ketones with an All-Carbon Quaternary Stereocenter by Engineered Amine Dehydrogenases

ACS catalysis, 2023-04, Vol.13 (7), p.5053-5061

2023

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Creating a new benzaldehyde lyase for atom-economic synthesis of chiral 1,2,4-butanetriol and 2-aminobutane-1,4-diol from formaldehyde

Chem catalysis, 2023-01, Vol.3 (1), p.100467, Article 100467

2023

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Research progress of the multifunctional oxidase scopolamine 6β-hydroxylase

Highly Efficient Enzymatic Synthesis of C6-Substituted Δ1‑3-Ketosteroids Enabled by Finely Tuning the Substrate Binding of 3‑Ketosteroid‑Δ1‑Dehydrogenase

Asymmetric carbohydroxylation of alkenes via sequential photocatalytic oxo-alkylation and enzymatic reduction

Manipulating Activity and Chemoselectivity of a Benzaldehyde Lyase for Efficient Synthesis of α‑Hydroxymethyl Ketones and One-Pot Enantio-Complementary Conversion to 1,2-Diols

Molecular modification of cyclodextrin glucosyltransferase and its application in the synthesis of α-arbutin

Identification and structure-based engineering of a dipeptidase CpPepD from Clostridium perfringens for the synthesis of l-carnosine

Biocatalytic production of (S)-1,2,4-butanetriol from d-xylose by whole cells of engineered Escherichia coli

Engineered Imine Reductase for Asymmetric Synthesis of Dextromethorphan Key Intermediate

Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols

Discovery and directed evolution of C-C bond formation enzymes for the biosynthesis of β-hydroxy-α-amino acids and derivatives

Engineering of halohydrin dehalogenases for the regio- and stereoselective synthesis of ()-4-aryl-2-oxazolidinones

Efficient synthesis of (R)-4-methoxyamphetamine and its analogues under low ammonium concentration using engineered amine dehydrogenase

Reshaping the Substrate Binding Pocket of β-Amino Acid Dehydrogenase for the Synthesis of Aromatic β-Amino Acids

Photoredox/Enzymatic Catalysis Enabling Redox-Neutral Decarboxylative Asymmetric C–C Coupling for Asymmetric Synthesis of Chiral 1,2-Amino Alcohols

The function of steroid terminal monooxygenase in cholesterol or phytosterol degradation by the Mycobacterium neoaurum NRRL B-3805

Semirational Engineering of a Thermostable Carbonyl Reductase for the Precision Synthesis of (2R,3R)‑2-Methyl-2-benzyl-3-hydroxycyclopentanone and Its Analogues

Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer

Efficient enzymatic synthesis of (S)-1-(3′-bromo-2′-methoxyphenyl)ethanol, the key building block of lusutrombopag

Stereocomplementary Synthesis of β‐Aryl Propanamines by Enzymatic Dynamic Kinetic Resolution‐Reductive Amination

Chemo-enzymatic synthesis of chiral 3-substituted tetrahydroquinolines by a sequential biocatalytic cascade and Buchwald-Hartwig cyclization

Structure-guided semi-rational design of an imine reductase for enantio-complementary synthesis of pyrrolidinamine

Enantiodivergent Synthesis of 1‑Heteroaryl Tetrahydroisoquinolines Catalyzed by Imine Reductases

Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4‑Aryl-2-oxazolidinones from Readily Available Epoxides

Desymmetric Reductive Amination of 1,3-Cyclopentadiones to Single Stereoisomer of β‑Amino Ketones with an All-Carbon Quaternary Stereocenter by Engineered Amine Dehydrogenases

Creating a new benzaldehyde lyase for atom-economic synthesis of chiral 1,2,4-butanetriol and 2-aminobutane-1,4-diol from formaldehyde

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