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Fact-checking chronotherapeutic research: Commentary on Bisdounis, et al. (2022)

Neuroscience and biobehavioral reviews, 2022-06, Vol.137, p.104673-104673, Article 104673

2022

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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (5), p.1542-1547

2009

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Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Nature (London), 2000-12, Vol.408 (6815), p.1004-1008

2000

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Regulation of the Apaf-1/Caspase-9 Apoptosome by Caspase-3 and XIAP

The Journal of biological chemistry, 2003-03, Vol.278 (10), p.8091-8098

2003

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Inefficient Reprogramming of Fibroblasts into Cardiomyocytes Using Gata4, Mef2c, and Tbx5

Circulation research, 2012-06, Vol.111 (1), p.50-55

2012

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Caspase Inhibition Reduces Tubular Apoptosis and Proliferation and Slows Disease Progression in Polycystic Kidney Disease

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (19), p.6954-6959

2005

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Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

Nature communications, 2015-07, Vol.6 (1), p.7645, Article 7645

2015

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Continuous fluorescence-based method for assessing Dicer cleavage efficiency reveals 3′ overhang nucleotide preference

BioTechniques, 2010-04, Vol.48 (4), p.303-311

2010

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Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

Protein science, 2010-04, Vol.19 (4), p.703-715

2010

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The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

Structure (London), 1999-09, Vol.7 (9), p.1125-1133

1999

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Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance

Journal of biochemistry (Tokyo), 2010-04, Vol.147 (4), p.601-609

2010

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Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit

Critical reviews in biochemistry and molecular biology, 2011-08, Vol.46 (4), p.295-309

2011

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Protein kinase inhibitors: breakthrough medicines and the next generation

Expert opinion on investigational drugs, 2013-06, Vol.22 (6), p.675-678

2013

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Structural and Functional Analysis of Caspase Active Sites

Biochemistry (Easton), 2003-04, Vol.42 (14), p.4151-4160

2003

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NMR Structure and Mutagenesis of the Third Bir Domain of the Inhibitor of Apoptosis Protein XIAP

The Journal of biological chemistry, 2000-10, Vol.275 (43), p.33777-33781

2000

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Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 2. Tricyclic pyridobenzoxazepinones and dibenzoxazepinones

Journal of medicinal chemistry, 1992-05, Vol.35 (10), p.1887-1897

1992

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Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG-out Conformation of p38α for High Throughput Screening Binding Assay

Chemical biology & drug design, 2009-12, Vol.74 (6), p.547-559

2009

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Enhanced selectivity profile of pyrazole-urea based DFG-out p38α inhibitors

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (16), p.4885-4891

2010

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Molecular Mechanisms of Resistance to Imatinib or Sunitinib in KIT Mutants from Patients with Gastrointestinal Stromal Tumors

The FASEB journal, 2010-04, Vol.24 (S1), p.307.2-307.2

Wu, Joe C

2010

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Conformational restrictions in the active site of unliganded human caspase-3

Journal of molecular recognition, 2003-05, Vol.16 (3), p.121-124

2003

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A Nucleotide Binding Site in Caspase-9 Regulates Apoptosome Activation

Biochemistry (Easton), 2005-04, Vol.44 (13), p.4971-4976

2005

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A simple kinetic method for rapid mechanistic analysis of reversible enzyme inhibitors

Assay and drug development technologies, 2003-08, Vol.1 (4), p.527-535

2003

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Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2685-2691

2004

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Structure-activity relationships within a series of caspase inhibitors: Effect of leaving group modifications

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (20), p.3623-3626

2003

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Acyl dipeptides as reversible caspase inhibitors. Part 1: Initial lead optimization

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (20), p.2969-2971

2002

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Fact-checking chronotherapeutic research: Commentary on Bisdounis, et al. (2022)

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Regulation of the Apaf-1/Caspase-9 Apoptosome by Caspase-3 and XIAP

Inefficient Reprogramming of Fibroblasts into Cardiomyocytes Using Gata4, Mef2c, and Tbx5

Caspase Inhibition Reduces Tubular Apoptosis and Proliferation and Slows Disease Progression in Polycystic Kidney Disease

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

Continuous fluorescence-based method for assessing Dicer cleavage efficiency reveals 3′ overhang nucleotide preference

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance

Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit

Protein kinase inhibitors: breakthrough medicines and the next generation

Structural and Functional Analysis of Caspase Active Sites

NMR Structure and Mutagenesis of the Third Bir Domain of the Inhibitor of Apoptosis Protein XIAP

Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 2. Tricyclic pyridobenzoxazepinones and dibenzoxazepinones

Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG-out Conformation of p38α for High Throughput Screening Binding Assay

Enhanced selectivity profile of pyrazole-urea based DFG-out p38α inhibitors

Molecular Mechanisms of Resistance to Imatinib or Sunitinib in KIT Mutants from Patients with Gastrointestinal Stromal Tumors

Conformational restrictions in the active site of unliganded human caspase-3

A Nucleotide Binding Site in Caspase-9 Regulates Apoptosome Activation

A simple kinetic method for rapid mechanistic analysis of reversible enzyme inhibitors

Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke

Structure-activity relationships within a series of caspase inhibitors: Effect of leaving group modifications

Acyl dipeptides as reversible caspase inhibitors. Part 1: Initial lead optimization

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