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Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1

Clinical lymphoma, myeloma and leukemia, 2015-06, Vol.15, p.S167-S169

2015

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A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models

Molecular cancer therapeutics, 2022-01, Vol.21 (1), p.113-124

2022

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Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (10), p.3990-3995

2007

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Synthesis and immunostimulatory activity of 8-substituted amino 9-benzyladenines as potent Toll-like receptor 7 agonists

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (17), p.4559-4563

2006

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Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.17266-17271

2014

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Abstract 489: Buoyant targeted microbubble technology provides efficient and superior quality of hematopoietic stem cells isolated from umbilical cord blood

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.489-489

2020

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Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (16), p.7479-7484

2010

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Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.6127-6132

2013

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Novel Dormancy Mechanism of Castration Resistance in Bone Metastatic Prostate Cancer Organoids

International journal of molecular sciences, 2022-03, Vol.23 (6), p.3203

2022

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Antitumor effect and mechanism of FZD7 polypeptide vaccine

Frontiers in oncology, 2022-10, Vol.12, p.925495-925495

2022

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Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates

Bioconjugate chemistry, 2009-06, Vol.20 (6), p.1194-1200

2009

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Activation of Anti-Hepatitis C Virus Responses via Toll-like Receptor 7

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (6), p.1828-1833

2006

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Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine

Cancer biology & medicine, 2020-02, Vol.17 (1), p.132-141

2020

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Inhibition of Wnt Signaling By Dimethyl Fumarate Results in in Vitro and in Vivo Clearance of Chronic Lymphocytic Leukemia Cells and Has Additive Activity with Ibrutinib

Blood, 2014-12, Vol.124 (21), p.4683-4683

2014

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Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib

Blood, 2013-11, Vol.122 (21), p.5306-5306

2013

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Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of Wnt/β-catenin signaling and CLL cell survival

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (3), p.606-609

2009

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Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Blood, 2013-11, Vol.122 (21), p.1637-1637

2013

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Necessity of Oligonucleotide Aggregation for Toll-like Receptor 9 Activation

The Journal of biological chemistry, 2004-08, Vol.279 (32), p.33071-33078

2004

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Increased Activity of Aldehyde Dehydrogenase, a Stem/Progenitor Cell Marker, in Chronic Lymphocytic Leukemia

Blood, 2011-11, Vol.118 (21), p.3867-3867

2011

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Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1

Blood, 2013-11, Vol.122 (21), p.2873-2873

2013

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Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody

Blood, 2012-11, Vol.120 (21), p.3886-3886

2012

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Innate Immune Protection against Infectious Diseases by Pulmonary Administration of a Phospholipid-Conjugated TLR7 Ligand

Journal of innate immunity, 2014-01, Vol.6 (3), p.315-324

2014

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Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

Blood, 2011-11, Vol.118 (21), p.984-984

2011

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A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Blood, 2011-11, Vol.118 (21), p.927-927

2011

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Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2

Melanoma research, 2011-02, Vol.21 (1), p.66-75

2011

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Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1

A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models

Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand

Synthesis and immunostimulatory activity of 8-substituted amino 9-benzyladenines as potent Toll-like receptor 7 agonists

Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy

Abstract 489: Buoyant targeted microbubble technology provides efficient and superior quality of hematopoietic stem cells isolated from umbilical cord blood

Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44

Novel Dormancy Mechanism of Castration Resistance in Bone Metastatic Prostate Cancer Organoids

Antitumor effect and mechanism of FZD7 polypeptide vaccine

Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates

Activation of Anti-Hepatitis C Virus Responses via Toll-like Receptor 7

Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine

Inhibition of Wnt Signaling By Dimethyl Fumarate Results in in Vitro and in Vivo Clearance of Chronic Lymphocytic Leukemia Cells and Has Additive Activity with Ibrutinib

Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib

Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of Wnt/β-catenin signaling and CLL cell survival

Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Necessity of Oligonucleotide Aggregation for Toll-like Receptor 9 Activation

Increased Activity of Aldehyde Dehydrogenase, a Stem/Progenitor Cell Marker, in Chronic Lymphocytic Leukemia

Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1

Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody

Innate Immune Protection against Infectious Diseases by Pulmonary Administration of a Phospholipid-Conjugated TLR7 Ligand

Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2

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