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Dysregulation of Rab5‐mediated endocytic pathways in Alzheimer's disease

Traffic (Copenhagen, Denmark), 2018-04, Vol.19 (4), p.253-262

2018

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Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration

Theranostics, 2020, Vol.10 (4), p.1649-1677

2020

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Charcot Marie Tooth 2B Peripheral Sensory Neuropathy: How Rab7 Mutations Impact NGF Signaling?

International journal of molecular sciences, 2017-02, Vol.18 (2), p.324-324

2017

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Current advances in using neurotrophic factors to treat neurodegenerative disorders

Translational neurodegeneration, 2012-07, Vol.1 (1), p.14-14, Article 14

2012

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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

The Journal of clinical investigation, 2016-05, Vol.126 (5), p.1815-1833

2016

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Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy

Nature communications, 2018-03, Vol.9 (1), p.1007-11, Article 1007

2018

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Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome

Nature medicine, 2013-04, Vol.19 (4), p.473-480

2013

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TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (38), p.E5655-E5664

2016

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Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing

The Journal of neuroscience, 2012-01, Vol.32 (4), p.1467-1480

2012

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BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons

eLife, 2023-02, Vol.12

2023

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Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease

Neurobiology of disease, 2023-10, Vol.186, p.106285-106285, Article 106285

2023

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One at a time, live tracking of NGF axonal transport using quantum dots

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (34), p.13666-13671

2007

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Editorial: Using novel technologies and models to identify biomarkers and explore therapeutic strategies for neurological disorders

Frontiers in behavioral neuroscience, 2023-03, Vol.17, p.1151667-1151667

2023

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Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR

Frontiers in molecular neuroscience, 2023-11, Vol.16, p.1241420-1241420

2023

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Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease

Scientific reports, 2017-06, Vol.7 (1), p.3868-13, Article 3868

2017

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CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons

Nature communications, 2023-02, Vol.14 (1), p.692-692, Article 692

2023

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Herpes Simplex Virus, Alzheimer's Disease and a Possible Role for Rab GTPases

Frontiers in cell and developmental biology, 2019-08, Vol.7, p.134-134

2019

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Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy

Neurobiology of disease, 2023-03, Vol.178, p.106010-106010, Article 106010

2023

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Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus

Neurobiology of disease, 2022-10, Vol.172, p.105834-105834, Article 105834

2022

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Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration

Neuron (Cambridge, Mass.), 2006-07, Vol.51 (1), p.29-42

2006

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Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease

Translational neurodegeneration, 2020-06, Vol.9 (1), p.1-26, Article 26

2020

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TrkB Binds and Tyrosine-Phosphorylates Tiam1, Leading to Activation of Rac1 and Induction of Changes in Cellular Morphology

Proceedings of the National Academy of Sciences - PNAS, 2006-07, Vol.103 (27), p.10444-10449

2006

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DORSAL ROOT GANGLION NEURONS FROM A HUNTINGTON’S DISEASE MOUSE MODEL SHOW DIFFERENCES IN THEIR CALCIUM RESPONSE TO AXONAL INJURY BY LASER INDUCED SHOCKWAVE

IBRO neuroscience reports, 2023-10, Vol.15, p.S417-S417

2023

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Exogenous fibroblast growth factor 1 ameliorates diabetes-induced cognitive decline via coordinately regulating PI3K/AKT signaling and PERK signaling

Cell communication and signaling, 2020-05, Vol.18 (1), p.81-81, Article 81

2020

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Uncoupling neurotrophic function from nociception of nerve growth factor: what can be learned from a rare human disease?

Neural regeneration research, 2019-04, Vol.14 (4), p.570-573

2019

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Dysregulation of Rab5‐mediated endocytic pathways in Alzheimer's disease

Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration

Charcot Marie Tooth 2B Peripheral Sensory Neuropathy: How Rab7 Mutations Impact NGF Signaling?

Current advances in using neurotrophic factors to treat neurodegenerative disorders

Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome

TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing

BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons

Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease

One at a time, live tracking of NGF axonal transport using quantum dots

Editorial: Using novel technologies and models to identify biomarkers and explore therapeutic strategies for neurological disorders

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR

Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease

CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons

Herpes Simplex Virus, Alzheimer's Disease and a Possible Role for Rab GTPases

Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy

Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus

Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease

TrkB Binds and Tyrosine-Phosphorylates Tiam1, Leading to Activation of Rac1 and Induction of Changes in Cellular Morphology

DORSAL ROOT GANGLION NEURONS FROM A HUNTINGTON’S DISEASE MOUSE MODEL SHOW DIFFERENCES IN THEIR CALCIUM RESPONSE TO AXONAL INJURY BY LASER INDUCED SHOCKWAVE

Exogenous fibroblast growth factor 1 ameliorates diabetes-induced cognitive decline via coordinately regulating PI3K/AKT signaling and PERK signaling

Uncoupling neurotrophic function from nociception of nerve growth factor: what can be learned from a rare human disease?

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