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Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

The pharmacogenomics journal, 2011-08, Vol.11 (4), p.274-286

2011

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In vitro glucuronidation using human liver microsomes and the pore-forming peptide alamethicin

Drug metabolism and disposition, 2000-05, Vol.28 (5), p.560

2000

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THE ROLE OF CYP2B6 IN HUMAN XENOBIOTIC METABOLISM

Drug metabolism reviews, 1999-01, Vol.31 (3), p.719-754

1999

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Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors

Drug metabolism and disposition, 2000-08, Vol.28 (8), p.994

2000

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Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities

The Journal of pharmacology and experimental therapeutics, 1999-08, Vol.290 (2), p.854

1999

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Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test

Drug metabolism and disposition, 1994-11, Vol.22 (6), p.947

1994

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The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism

Drug metabolism reviews, 2001-01, Vol.33 (3-4), p.273-297

2001

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Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey

Drug metabolism and disposition, 1995-11, Vol.23 (11), p.1231

1995

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Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450

The Journal of pharmacology and experimental therapeutics, 1993-08, Vol.266 (2), p.964

1993

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Three-dimensional-quantitative structure activity relationship analysis of cytochrome P-450 3A4 substrates

The Journal of pharmacology and experimental therapeutics, 1999-10, Vol.291 (1), p.424

1999

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Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine

Pharmaceutical research, 1994-06, Vol.11 (6), p.921-924

1994

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The use of human hepatocyte cultures to study the induction of cytochrome P-450

Drug metabolism and disposition, 1999-08, Vol.27 (8), p.887

1999

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Nature genetics, 2001-04, Vol.27 (4), p.383-391

2001

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Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily

Biochemical pharmacology, 1994-04, Vol.47 (9), p.1643-1653

1994

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Isolation and Characterization of Human Liver Cytochrome P450 2C19: Correlation between 2C19 and S-Mephenytoin 4′-Hydroxylation

Archives of biochemistry and biophysics, 1993-10, Vol.306 (1), p.240-245

1993

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Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine

The Journal of pharmacology and experimental therapeutics, 1996-02, Vol.276 (2), p.658

1996

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Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)

Molecular pharmacology, 1990-08, Vol.38 (2), p.207-213

1990

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Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases: Comparison of human liver and kidney microsomes and mammalian enzymes

Biochemical pharmacology, 2000-07, Vol.60 (1), p.7-17

2000

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Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily

Xenobiotica, 1999, Vol.29 (9), p.931-944

1999

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Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450: studies in rats and patients

The Journal of clinical investigation, 1989-02, Vol.83 (2), p.688-697

1989

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Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

The Journal of clinical investigation, 1987-10, Vol.80 (4), p.1029-1036

1987

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Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine

Drug metabolism and disposition, 1996-04, Vol.24 (4), p.487

1996

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Bimodal distribution of renal cytochrome P450 3A activity in humans

Molecular pharmacology, 1996-07, Vol.50 (1), p.52-59

1996

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Identification of a polymorphically expressed member of the human cytochrome P-450III family

Molecular pharmacology, 1989-07, Vol.36 (1), p.97-105

1989

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Autoactivation and activation of the cytochrome P450s

International journal of clinical pharmacology and therapeutics, 1998-12, Vol.36 (12), p.642

1998

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Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

In vitro glucuronidation using human liver microsomes and the pore-forming peptide alamethicin

THE ROLE OF CYP2B6 IN HUMAN XENOBIOTIC METABOLISM

Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors

Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test

The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism

Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey

Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450

Three-dimensional-quantitative structure activity relationship analysis of cytochrome P-450 3A4 substrates

Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine

The use of human hepatocyte cultures to study the induction of cytochrome P-450

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily

Isolation and Characterization of Human Liver Cytochrome P450 2C19: Correlation between 2C19 and S-Mephenytoin 4′-Hydroxylation

Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine

Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)

Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases: Comparison of human liver and kidney microsomes and mammalian enzymes

Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450: studies in rats and patients

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine

Bimodal distribution of renal cytochrome P450 3A activity in humans

Identification of a polymorphically expressed member of the human cytochrome P-450III family

Autoactivation and activation of the cytochrome P450s

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