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Calpain Regulation and Dysregulation-Its Effects on the Intercalated Disk

International journal of molecular sciences, 2023-07, Vol.24 (14), p.11726

2023

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A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy

PloS one, 2017-10, Vol.12 (10), p.e0186642-e0186642

2017

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Biophysical characterization of naturally occurring titin M10 mutations

Protein science, 2015-06, Vol.24 (6), p.946-955

2015

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Bringing biophysics outreach to a county fair

Biophysical journal, 2023-02, Vol.122 (3), p.555a-555a

Wright, Nathan T.

2023

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Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway

Journal of molecular and cellular cardiology, 2017-10, Vol.111, p.27-39

2017

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Case Report: Two Families With HPDL Related Neurodegeneration

Frontiers in genetics, 2022-02, Vol.13, p.780764

2022

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S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor

The Journal of biological chemistry, 2008-09, Vol.283 (39), p.26676-26683

2008

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Microscopic springs: Investigating viscoelastic and elastic tendencies of the cell membrane

Biophysical journal, 2023-02, Vol.122 (3), p.363a-364a

2023

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Prevention of Protease-Induced Degradation of Desmoplakin via Small Molecule Binding

Journal of personalized medicine, 2024-01, Vol.14 (2), p.163

2024

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Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4

Journal of Virology, 2003-02, Vol.77 (3), p.1812-1819

2003

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S100A1 Binds to the Calmodulin-binding Site of Ryanodine Receptor and Modulates Skeletal Muscle Excitation-Contraction Coupling

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.5046-5057

2008

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Creating a ‘Molecular Band-Aid’; Blocking an Exposed Protease Target Site in Desmoplakin

Journal of personalized medicine, 2021-05, Vol.11 (5), p.401

2021

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Quantifying obscurin's impact on epithelial cell area, perimeter & localization with the cell membrane

Biophysical journal, 2023-02, Vol.122 (3), p.469a-469a

2023

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Insights into cis-autoproteolysis reveal a reactive state formed through conformational rearrangement

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2308-2313

2012

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Investigating obscurin's modulation through the RhoA pathway

Biophysical journal, 2023-02, Vol.122 (3), p.265a-266a

2023

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Bandaids on broken hearts: Preventing protease-mediated degradation of desmoplakin with small molecules

Biophysical journal, 2023-02, Vol.122 (3), p.339a-339a

2023

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Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis

Journal of molecular biology, 2012-09, Vol.422 (4), p.508-518

2012

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Compound heterozygous variants in MYBPC1 lead to severe distal arthrogryposis type-1 manifestations

Gene, 2024-06, Vol.910, p.148339-148339, Article 148339

2024

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A Perspective on Developing Modeling and Image Analysis Tools to Investigate Mechanosensing Proteins

Integrative and comparative biology, 2023-12, Vol.63 (6), p.1532

2023

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Heteronuclear Multidimensional Protein NMR in a Teaching Laboratory

Journal of chemical education, 2016-02, Vol.93 (2), p.287-291

Wright, Nathan T

2016

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The N‐terminus of obscurin is flexible in solution

Proteins, structure, function, and bioinformatics, 2023-04, Vol.91 (4), p.485-496

2023

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Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

Annals of neurology, 2019-07, Vol.86 (1), p.129-142

2019

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Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome

Blood, 2021-11, Vol.138 (21), p.2117-2128

2021

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Structure of giant muscle proteins

Frontiers in physiology, 2013-12, Vol.4, p.368-368

2013

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Mechanical dissociation of the M-band titin/obscurin complex is directionally dependent

FEBS letters, 2015-07, Vol.589 (15), p.1735-1739

2015

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Calpain Regulation and Dysregulation-Its Effects on the Intercalated Disk

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy

Biophysical characterization of naturally occurring titin M10 mutations

Bringing biophysics outreach to a county fair

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway

Case Report: Two Families With HPDL Related Neurodegeneration

S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor

Microscopic springs: Investigating viscoelastic and elastic tendencies of the cell membrane

Prevention of Protease-Induced Degradation of Desmoplakin via Small Molecule Binding

Overlapping Motifs (PTAP and PPEY) within the Ebola Virus VP40 Protein Function Independently as Late Budding Domains: Involvement of Host Proteins TSG101 and VPS-4

S100A1 Binds to the Calmodulin-binding Site of Ryanodine Receptor and Modulates Skeletal Muscle Excitation-Contraction Coupling

Creating a ‘Molecular Band-Aid’; Blocking an Exposed Protease Target Site in Desmoplakin

Quantifying obscurin's impact on epithelial cell area, perimeter & localization with the cell membrane

Insights into cis-autoproteolysis reveal a reactive state formed through conformational rearrangement

Investigating obscurin's modulation through the RhoA pathway

Bandaids on broken hearts: Preventing protease-mediated degradation of desmoplakin with small molecules

Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis

Compound heterozygous variants in MYBPC1 lead to severe distal arthrogryposis type-1 manifestations

A Perspective on Developing Modeling and Image Analysis Tools to Investigate Mechanosensing Proteins

Heteronuclear Multidimensional Protein NMR in a Teaching Laboratory

The N‐terminus of obscurin is flexible in solution

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome

Structure of giant muscle proteins

Mechanical dissociation of the M-band titin/obscurin complex is directionally dependent

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