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Hexadecylphosphocholine (Miltefosine) Has Broad-Spectrum Fungicidal Activity and Is Efficacious in a Mouse Model of Cryptococcosis

Antimicrobial Agents and Chemotherapy, 2006-02, Vol.50 (2), p.414-421

2006

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Cell Wall-linked Cryptococcal Phospholipase B1 Is a Source of Secreted Enzyme and a Determinant of Cell Wall Integrity

The Journal of biological chemistry, 2007-12, Vol.282 (52), p.37508-37514

2007

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Lipid Rafts in Cryptococcus neoformans Concentrate the Virulence Determinants Phospholipase B1 and Cu/Zn Superoxide Dismutase

Eukaryotic Cell, 2006-03, Vol.5 (3), p.488-498

2006

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Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor

Biochemical journal, 2005-08, Vol.389 (Pt 3), p.803-812

2005

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In Vitro Activities of Miltefosine and Two Novel Antifungal Biscationic Salts against a Panel of 77 Dermatophytes

Antimicrobial Agents and Chemotherapy, 2007-06, Vol.51 (6), p.2219-2222

2007

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Cryptococcal Lipid Metabolism: Phospholipase B1 Is Implicated in Transcellular Metabolism of Macrophage-Derived Lipids

Eukaryotic Cell, 2007-01, Vol.6 (1), p.37-47

2007

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Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii

Biochemical journal, 2004-12, Vol.384 (Pt 2), p.377-384

2004

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Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans

Molecular microbiology, 2001-01, Vol.39 (1), p.166-175

2001

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Synthesis, antifungal and antimicrobial activity of alkylphospholipids

Bioorganic & medicinal chemistry, 2007-08, Vol.15 (15), p.5158-5165

2007

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Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes

Bioorganic & medicinal chemistry, 2007-05, Vol.15 (10), p.3422-3429

2007

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N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring

Biochimica et biophysica acta, 2006-10, Vol.1760 (10), p.1569-1579

2006

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Correlation of Antifungal Activity with Fungal Phospholipase Inhibition Using a Series of Bisquaternary Ammonium Salts

Journal of medicinal chemistry, 2006-01, Vol.49 (2), p.811-816

2006

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Application of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis

FEMS yeast research, 2006-06, Vol.6 (4), p.558-566

2006

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Phospholipase Activity in Cryptococcus neoformans: A New Virulence Factor?

The Journal of infectious diseases, 1997-02, Vol.175 (2), p.414-420

1997

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Role of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformans

Biochemistry (Easton), 2007-09, Vol.46 (35), p.10024-10032

2007

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Inhibition of tetraphenylphosphonium-induced NMR-visible lipid accumulation in human breast cells by chlorpromazine

Biochimica et biophysica acta, 2003-09, Vol.1633 (3), p.149-160

2003

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Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans

Gene, 2003-10, Vol.316, p.67-78

2003

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Organization of lipids in the plasma membranes of malignant and stimulated cells: a new model

Trends in Biochemical Sciences, 1988-05, Vol.13 (5), p.172-177

1988

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Biochemical and Functional Characterisation of Secreted Phospholipase Activities from Cryptococcus Neoformans in their Naturally Occurring State

Journal of medical microbiology, 1999-08, Vol.48 (8), p.731-740

1999

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Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans

FEMS microbiology letters, 2002-04, Vol.209 (2), p.175-181

2002

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Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans

Biochemical journal, 2000-04, Vol.347 (Pt 2), p.431-439

2000

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Detergent‐resistant membrane fractions contribute to the total 1H NMR‐visible lipid signal in cells

European journal of biochemistry, 2003-05, Vol.270 (9), p.2091-2100

2003

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High-Resolution Proton Nuclear Magnetic Resonance Analysis of Metastatic Cancer Cells

Science (American Association for the Advancement of Science), 1984-12, Vol.226 (4681), p.1415-1418

1984

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Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans

Infection and Immunity, 1997-02, Vol.65 (2), p.405-411

1997

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Detection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA)

Medical mycology (Oxford), 2005-06, Vol.43 (4), p.335-341

2005

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Hexadecylphosphocholine (Miltefosine) Has Broad-Spectrum Fungicidal Activity and Is Efficacious in a Mouse Model of Cryptococcosis

Cell Wall-linked Cryptococcal Phospholipase B1 Is a Source of Secreted Enzyme and a Determinant of Cell Wall Integrity

Lipid Rafts in Cryptococcus neoformans Concentrate the Virulence Determinants Phospholipase B1 and Cu/Zn Superoxide Dismutase

Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor

In Vitro Activities of Miltefosine and Two Novel Antifungal Biscationic Salts against a Panel of 77 Dermatophytes

Cryptococcal Lipid Metabolism: Phospholipase B1 Is Implicated in Transcellular Metabolism of Macrophage-Derived Lipids

Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii

Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans

Synthesis, antifungal and antimicrobial activity of alkylphospholipids

Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes

N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring

Correlation of Antifungal Activity with Fungal Phospholipase Inhibition Using a Series of Bisquaternary Ammonium Salts

Application of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis

Phospholipase Activity in Cryptococcus neoformans: A New Virulence Factor?

Role of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformans

Inhibition of tetraphenylphosphonium-induced NMR-visible lipid accumulation in human breast cells by chlorpromazine

Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans

Organization of lipids in the plasma membranes of malignant and stimulated cells: a new model

Biochemical and Functional Characterisation of Secreted Phospholipase Activities from Cryptococcus Neoformans in their Naturally Occurring State

Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans

Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans

Detergent‐resistant membrane fractions contribute to the total 1H NMR‐visible lipid signal in cells

High-Resolution Proton Nuclear Magnetic Resonance Analysis of Metastatic Cancer Cells

Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans

Detection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA)

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