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Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS

PLoS biology, 2019-02, Vol.17 (2), p.e3000141

2019

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Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota

Nature chemical biology, 2022-08, Vol.18 (8), p.841

2022

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Identification of D-arabinan-degrading enzymes in mycobacteria

Nature communications, 2023-04, Vol.14 (1), p.2233-2233, Article 2233

2023

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Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis

ACS catalysis, 2019-07, Vol.9 (7), p.6087-6099

2019

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The biophysics of superoxide dismutase-1 and amyotrophic lateral sclerosis

Quarterly reviews of biophysics, 2019-11, Vol.52, p.e12, Article e12

2019

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Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy

Communications biology, 2020-03, Vol.3 (1), p.97-97, Article 97

2020

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The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation

Nature communications, 2018-04, Vol.9 (1), p.1693-9, Article 1693

2018

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The structural plasticity of the human copper chaperone for SOD1: insights from combined size-exclusion chromatographic and solution X-ray scattering studies

Biochemical journal, 2011-10, Vol.439 (1), p.39-44

2011

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Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol

Scientific reports, 2017-03, Vol.7 (1), p.43580, Article 43580

2017

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Crystal Structure of the Japanese Encephalitis Virus Capsid Protein

Viruses, 2019-07, Vol.11 (7), p.623

2019

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Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4309-4314

2014

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A faulty interaction between SOD1 and hCCS in neurodegenerative disease

Scientific reports, 2016-06, Vol.6 (1), p.27691-27691, Article 27691

2016

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LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single‐particle cryo‐EM

Acta crystallographica. Section D, Biological crystallography., 2019-07, Vol.75 (7), p.660-669

2019

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The application of hybrid pixel detectors for in-house SAXS instrumentation with a view to combined chromatographic operation

Journal of synchrotron radiation, 2013-03, Vol.20 (2), p.383-385

2013

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Bacterial Evolutionary Precursors of Eukaryotic Copper–Zinc Superoxide Dismutases

Molecular biology and evolution, 2021-09, Vol.38 (9), p.3789-3803

2021

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Molecular and pharmacological chaperones for SOD1

Biochemical Society transactions, 2020-08, Vol.48 (4), p.1795-1806

Wright, Gareth S.A.

2020

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Characterization of a novel copper-haem c dissimilatory nitrite reductase from Ralstonia pickettii

Biochemical journal, 2012-06, Vol.444 (2), p.219-226

2012

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Ligand binding and aggregation of pathogenic SOD1

Nature communications, 2013, Vol.4 (1), p.1758, Article 1758

2013

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Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation

FEBS letters, 2018-05, Vol.592 (10), p.1725-1737

2018

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Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus

Journal of virology, 2018-04, Vol.92 (7)

2018

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Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis

Journal of biomolecular structure & dynamics, 2019-10, Vol.37 (15), p.3936-3946

2019

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Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases

iScience, 2020-06, Vol.23 (6), p.101159-101159, Article 101159

2020

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Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism

Analytical methods, 2015-01, Vol.7 (5), p.1667-1671

2015

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A high-throughput assay of membrane protein stability

Molecular membrane biology, 2008-01, Vol.25 (8), p.617-624

2008

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Reliable scale-up of membrane protein over-expression by bacterial auto-induction: From microwell plates to pilot scale fermentations

Molecular membrane biology, 2008-01, Vol.25 (8), p.588-598

2008

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Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota

Identification of D-arabinan-degrading enzymes in mycobacteria

Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis

The biophysics of superoxide dismutase-1 and amyotrophic lateral sclerosis

Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy

The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation

The structural plasticity of the human copper chaperone for SOD1: insights from combined size-exclusion chromatographic and solution X-ray scattering studies

Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol

Crystal Structure of the Japanese Encephalitis Virus Capsid Protein

Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life

A faulty interaction between SOD1 and hCCS in neurodegenerative disease

LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single‐particle cryo‐EM

The application of hybrid pixel detectors for in-house SAXS instrumentation with a view to combined chromatographic operation

Bacterial Evolutionary Precursors of Eukaryotic Copper–Zinc Superoxide Dismutases

Molecular and pharmacological chaperones for SOD1

Characterization of a novel copper-haem c dissimilatory nitrite reductase from Ralstonia pickettii

Ligand binding and aggregation of pathogenic SOD1

Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation

Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus

Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis

Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases

Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism

A high-throughput assay of membrane protein stability

Reliable scale-up of membrane protein over-expression by bacterial auto-induction: From microwell plates to pilot scale fermentations

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