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Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit

Science (American Association for the Advancement of Science), 2015-04, Vol.348 (6231), p.239-242

2015

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Signals to promote myelin formation and repair

Nature reviews. Neurology, 2010-05, Vol.6 (5), p.276

2010

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Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease

Nature communications, 2020-10, Vol.11 (1), p.5356-5356, Article 5356

2020

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Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells

Nature communications, 2021-06, Vol.12 (1), p.3285-3285, Article 3285

2021

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YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

Nature neuroscience, 2016-07, Vol.19 (7), p.879

2016

Volltextzugriff (PDF)

Molecular mechanisms of inherited demyelinating neuropathies

Glia, 2008-11, Vol.56 (14), p.1578-1589

2008

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Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination

eLife, 2021-09, Vol.10

2021

Volltextzugriff (PDF)

CHOP and the endoplasmic reticulum stress response in myelinating glia

Current opinion in neurobiology, 2009-10, Vol.19 (5), p.505-510

2009

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Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice

The Journal of experimental medicine, 2013-04, Vol.210 (4), p.821-838

2013

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Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

Neuron (Cambridge, Mass.), 2020-07, Vol.107 (1), p.65-81.e9

2020

Volltextzugriff (PDF)

Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration

PLoS biology, 2022-07, Vol.20 (7), p.e3001661-e3001661

2022

Volltextzugriff (PDF)

Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease

Orphanet journal of rare diseases, 2018-02, Vol.13 (1), p.30-30, Article 30

2018

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c-Jun is a negative regulator of myelination

The Journal of cell biology, 2008-05, Vol.181 (4), p.625-637

2008

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Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

PLoS biology, 2017-06, Vol.15 (6), p.e2001408-e2001408

2017

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Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

Nature neuroscience, 2009-07, Vol.12 (7), p.839-847

2009

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Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice

Neuron (Cambridge, Mass.), 2008-02, Vol.57 (3), p.393-405

2008

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Impairment of protein degradation and proteasome function in hereditary neuropathies

Glia, 2018-02, Vol.66 (2), p.379-395

2018

Volltextzugriff (PDF)

A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication

PLoS genetics, 2022-11, Vol.18 (11), p.e1010477-e1010477

2022

Volltextzugriff (PDF)

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice

Brain (London, England : 1878), 2012-12, Vol.135 (12), p.3551-3566

2012

Volltextzugriff (PDF)

Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration

The Journal of neuroscience, 2011-02, Vol.31 (6), p.2009-2015

2011

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The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease

Brain (London, England : 1878), 2014-03, Vol.137 (Pt 3), p.668-682

2014

Volltextzugriff (PDF)

DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination

The Journal of neuroscience, 2013-09, Vol.33 (38), p.15295-15305

2013

Volltextzugriff (PDF)

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin

The Journal of cell biology, 2015-02, Vol.208 (3), p.313-329

2015

Volltextzugriff (PDF)

β1 Integrin Activates Rac1 in Schwann Cells to Generate Radial Lamellae during Axonal Sorting and Myelination

The Journal of cell biology, 2007-06, Vol.177 (6), p.1063-1075

2007

Volltextzugriff (PDF)

Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy

Human molecular genetics, 2015-01, Vol.24 (2), p.383-396

2015

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Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit

Signals to promote myelin formation and repair

Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease

Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

Molecular mechanisms of inherited demyelinating neuropathies

Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination

CHOP and the endoplasmic reticulum stress response in myelinating glia

Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice

Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration

Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease

c-Jun is a negative regulator of myelination

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice

Impairment of protein degradation and proteasome function in hereditary neuropathies

A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice

Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration

The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease

DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin

β1 Integrin Activates Rac1 in Schwann Cells to Generate Radial Lamellae during Axonal Sorting and Myelination

Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy

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