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Delivery of bone morphogenetic proteins for orthopedic tissue regeneration

Cytokine & growth factor reviews, 2005-06, Vol.16 (3), p.329-345

2005

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Overview of bone morphogenetic proteins

Spine (Philadelphia, Pa. 1976), 2002-08, Vol.27 (16 Suppl 1), p.S2-S8

Wozney, John M

2002

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A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix

Science translational medicine, 2019-04, Vol.11 (489)

2019

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BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2

Biochemical and biophysical research communications, 2003-09, Vol.309 (3), p.689-694

2003

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rhBMP-12 accelerates healing of rotator cuff repairs in a sheep model

Journal of bone and joint surgery. American volume, 2008-10, Vol.90 (10), p.2206

2008

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Delivering on the promise of bone morphogenetic proteins

Trends in Biotechnology, 2001-07, Vol.19 (7), p.255-265

2001

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Bone Morphogenetic Protein-2-induced Alkaline Phosphatase Expression Is Stimulated by Dlx5 and Repressed by Msx2

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.50773-50780

2004

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Dlx5 Specifically Regulates Runx2 Type II Expression by Binding to Homeodomain-response Elements in the Runx2 Distal Promoter

The Journal of biological chemistry, 2005-10, Vol.280 (42), p.35579-35587

2005

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Bone reconstruction following implantation of rhBMP-2 and guided bone regeneration in canine alveolar ridge defects

Clinical oral implants research, 2007-04, Vol.18 (2), p.224-230

2007

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Bone formation at rhBMP-2-coated titanium implants in the rat ectopic model

Journal of clinical periodontology, 2007-05, Vol.34 (5), p.444-451

2007

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Bone formation at recombinant human bone morphogenetic protein-2-coated titanium implants in the posterior mandible (Type II bone) in dogs

Journal of clinical periodontology, 2008-11, Vol.35 (11), p.985-991

2008

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A Phase I/II trial of MYO-029 in Adult Subjects with Muscular Dystrophy

Annals of neurology, 2008-05, Vol.63 (5), p.561-571

2008

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Effect of Recombinant Human Bone Morphogenetic Protein‐2/Absorbable Collagen Sponge (rhBMP‐2/ACS) on Healing in 3‐Wall Intrabony Defects in Dogs

Journal of periodontology (1970), 2002-01, Vol.73 (1), p.63-72

2002

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Bone Repair Following Recombinant Human Bone Morphogenetic Protein‐2 Stimulated Periodontal Regeneration

Journal of periodontology (1970), 2002-09, Vol.73 (9), p.1020-1029

2002

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Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis

Journal of orthopaedic research, 2002-07, Vol.20 (4), p.779-788

2002

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Periodontal repair in dogs: evaluation of a bioresorbable calcium phosphate cement (CeredexTM) as a carrier for rhBMP-2

Journal of clinical periodontology, 2004-09, Vol.31 (9), p.796-804

2004

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Evaluation of Recombinant Human Bone Morphogenetic Protein‐2 on the Repair of Alveolar Ridge Defects in Baboons

Journal of periodontology (1970), 2005-02, Vol.76 (2), p.210-220

2005

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Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair

Clinical orthopaedics and related research, 1998-01, Vol.346 (346), p.26-37

1998

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Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations

Journal of clinical periodontology, 2008-11, Vol.35 (11), p.1001-1010

2008

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rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model

Journal of bone and joint surgery. American volume, 2010-02, Vol.92 (2), p.411

2010

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Novel Regulators of Bone Formation: Molecular Clones and Activities

Science (American Association for the Advancement of Science), 1988-12, Vol.242 (4885), p.1528-1534

1988

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Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12

Molecular and Cellular Biology, 2000-12, Vol.20 (23), p.8783-8792

2000

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BMP-2-induced Runx2 Expression Is Mediated by Dlx5, and TGF-β1 Opposes the BMP-2-induced Osteoblast Differentiation by Suppression of Dlx5 Expression

The Journal of biological chemistry, 2003-09, Vol.278 (36), p.34387-34394

2003

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Peri-implant bone regeneration using recombinant human bone morphogenetic protein-2 in a canine model: a dose-response study

Journal of periodontal research, 2002-04, Vol.37 (2), p.93-100

2002

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Protein-based tissue engineering in bone and cartilage repair

Current opinion in biotechnology, 2004-10, Vol.15 (5), p.392-398

2004

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Delivery of bone morphogenetic proteins for orthopedic tissue regeneration

Overview of bone morphogenetic proteins

A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix

BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2

rhBMP-12 accelerates healing of rotator cuff repairs in a sheep model

Delivering on the promise of bone morphogenetic proteins

Bone Morphogenetic Protein-2-induced Alkaline Phosphatase Expression Is Stimulated by Dlx5 and Repressed by Msx2

Dlx5 Specifically Regulates Runx2 Type II Expression by Binding to Homeodomain-response Elements in the Runx2 Distal Promoter

Bone reconstruction following implantation of rhBMP-2 and guided bone regeneration in canine alveolar ridge defects

Bone formation at rhBMP-2-coated titanium implants in the rat ectopic model

Bone formation at recombinant human bone morphogenetic protein-2-coated titanium implants in the posterior mandible (Type II bone) in dogs

A Phase I/II trial of MYO-029 in Adult Subjects with Muscular Dystrophy

Effect of Recombinant Human Bone Morphogenetic Protein‐2/Absorbable Collagen Sponge (rhBMP‐2/ACS) on Healing in 3‐Wall Intrabony Defects in Dogs

Bone Repair Following Recombinant Human Bone Morphogenetic Protein‐2 Stimulated Periodontal Regeneration

Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis

Periodontal repair in dogs: evaluation of a bioresorbable calcium phosphate cement (CeredexTM) as a carrier for rhBMP-2

Evaluation of Recombinant Human Bone Morphogenetic Protein‐2 on the Repair of Alveolar Ridge Defects in Baboons

Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair

Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations

rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model

Novel Regulators of Bone Formation: Molecular Clones and Activities

Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12

BMP-2-induced Runx2 Expression Is Mediated by Dlx5, and TGF-β1 Opposes the BMP-2-induced Osteoblast Differentiation by Suppression of Dlx5 Expression

Peri-implant bone regeneration using recombinant human bone morphogenetic protein-2 in a canine model: a dose-response study

Protein-based tissue engineering in bone and cartilage repair

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