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Identification of an orally active, nonpeptidyl oxytocin antagonist

The Journal of pharmacology and experimental therapeutics, 1993-01, Vol.264 (1), p.308

1993

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Nonpeptide oxytocin antagonists: Analogs of L-371,257 with improved potency

Bioorganic & medicinal chemistry letters, 1999-05, Vol.9 (9), p.1311-1316

1999

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Nonpeptide oxytocin antagonists: Potent, orally bioavailable analogs of L-371,257 containing A 1- R-(pyridyl)ethyl ether terminus

Bioorganic & medicinal chemistry letters, 1998-11, Vol.8 (21), p.3081-3086

1998

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Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Journal of medicinal chemistry, 1998-06, Vol.41 (12), p.2146-2163

1998

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In vitro pharmacological profile of a novel structural class of oxytocin antagonists

The Journal of pharmacology and experimental therapeutics, 1991-01, Vol.256 (1), p.304

1991

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L-368,899, a potent orally active oxytocin antagonist for potential use in preterm labor

Drug development research, 1993-11, Vol.30 (3), p.129-142

1993

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Cloning and Expression of the Rhesus Monkey Oxytocin Receptor

Journal of receptors and signal transduction, 1998, Vol.18 (1), p.15-24

1998

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Identification of functional oxytocin receptors in lactating rat mammary gland in vitro

European journal of pharmacology, 1990-04, Vol.188 (4-5), p.235-241

1990

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1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4634-4636

1995

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Radioligand binding studies reveal marked species differences in the vasopressin V1 receptor of rat, rhesus and human tissues

Life sciences (1973), 1992, Vol.50 (25), p.1953-1958

1992

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Development of orally active oxytocin antagonists : Studies on 1-(1-{4-[1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2-methoxybenzo yl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and related pyridines

Journal of medicinal chemistry, 1998, Vol.41 (12), p.2146-2163

1998

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Progress in the development of oxytocin antagonists for use in preterm labor

Advances in experimental medicine and biology, 1995, Vol.395, p.601

1995

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Radioligand binding studies reveal marked species differences in the vasopressin V sub(1) receptor of rat, rhesus and human tissues

Life sciences (1973), 1992-01, Vol.50 (25), p.1953-1958

1992

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Radioligand binding studies reveal marked species differences in the vasoprressin V1 receptor of rat, rhesus and human tissues

Life sciences (1973), 1992, Vol.50 (25), p.1953-1958

1992

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ChemInform Abstract: 1-(1-(4-((N-Acetyl-4-piperidinyl)oxy)-2-methoxybenzoyl)piperidin-4-yl)- 4H-3,1-benzoxazin-2(1H)-one (L-371,257): A New, Orally Bioavailable, Non-Peptide Oxytocin Antagonist

ChemInform, 1996-03, Vol.27 (11), p.no-no

1996

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Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective α1a-Receptor antagonists

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.1917-1920

2000

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Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective alpha1a-receptor antagonists

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.1917-1920

2000

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Identification of an orally active, nonpeptidyl oxytocin antagonist

Nonpeptide oxytocin antagonists: Analogs of L-371,257 with improved potency

Nonpeptide oxytocin antagonists: Potent, orally bioavailable analogs of L-371,257 containing A 1- R-(pyridyl)ethyl ether terminus

Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

In vitro pharmacological profile of a novel structural class of oxytocin antagonists

L-368,899, a potent orally active oxytocin antagonist for potential use in preterm labor

Cloning and Expression of the Rhesus Monkey Oxytocin Receptor

Identification of functional oxytocin receptors in lactating rat mammary gland in vitro

1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

Radioligand binding studies reveal marked species differences in the vasopressin V1 receptor of rat, rhesus and human tissues

Development of orally active oxytocin antagonists : Studies on 1-(1-{4-[1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2-methoxybenzo yl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and related pyridines

Progress in the development of oxytocin antagonists for use in preterm labor

Radioligand binding studies reveal marked species differences in the vasopressin V sub(1) receptor of rat, rhesus and human tissues

Radioligand binding studies reveal marked species differences in the vasoprressin V1 receptor of rat, rhesus and human tissues

ChemInform Abstract: 1-(1-(4-((N-Acetyl-4-piperidinyl)oxy)-2-methoxybenzoyl)piperidin-4-yl)- 4H-3,1-benzoxazin-2(1H)-one (L-371,257): A New, Orally Bioavailable, Non-Peptide Oxytocin Antagonist

Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective α1a-Receptor antagonists

Preparation and evaluation of 1,3-diaminocyclopentane-linked dihydropyrimidinone derivatives as selective alpha1a-receptor antagonists

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