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Translation control of the immune checkpoint in cancer and its therapeutic targeting

Nature medicine, 2019-02, Vol.25 (2), p.301-311

2019

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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

Cell reports (Cambridge), 2021-06, Vol.35 (13), p.109321-109321, Article 109321

2021

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Serum interleukin-4 is elevated in clinical drug-induced liver injury

Scandinavian journal of gastroenterology, 2023-12, Vol.ahead-of-print (ahead-of-print), p.1-6

2023

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Antibiotic Allergy Labels in a Liver Transplant Recipient Study

Antimicrobial agents and chemotherapy, 2017-05, Vol.61 (5)

2017

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Epidemiology and outcomes of primary sclerosing cholangitis: an Australian multicentre retrospective cohort study

Hepatology international, 2022-10, Vol.16 (5), p.1094-1104

2022

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Structure-Assisted Design of Mechanism-Based Irreversible Inhibitors of Human Rhinovirus 3C Protease with Potent Antiviral Activity against Multiple Rhinovirus Serotypes

Proceedings of the National Academy of Sciences - PNAS, 1999-09, Vol.96 (20), p.11000-11007

1999

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In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

Antimicrobial Agents and Chemotherapy, 1999-10, Vol.43 (10), p.2444-2450

1999

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

Journal of medicinal chemistry, 2002-04, Vol.45 (8), p.1607-1623

2002

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Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Journal of medicinal chemistry, 1996-12, Vol.39 (26), p.5072-5082

1996

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P1 Lactam Moieties as l-Glutamine Replacements

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1213-1224

1999

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Inhibition of Human Rhinovirus-Induced Cytokine Production by AG7088, a Human Rhinovirus 3C Protease Inhibitor

Antimicrobial Agents and Chemotherapy, 2000-05, Vol.44 (5), p.1236-1241

2000

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1203-1212

1999

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2806-2818

1998

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Effects of different Rht-B1b, Rht-D1b and Rht-B1c dwarfing genes on agronomic characteristics in wheat

Cereal research communications, 2006-01, Vol.34 (2-3), p.919-924

2006

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Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae

The Journal of biological chemistry, 1989-03, Vol.264 (8), p.4412-4416

1989

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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2786-2805

1998

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2819-2834

1998

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure–Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (5), p.733-738

2002

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Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1670-1683

2000

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Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (1), p.45-48

2000

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Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.2016-2023

2002

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Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2189-2194

1999

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Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2683-2686

2001

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Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides

Bioorganic & medicinal chemistry, 1999-04, Vol.7 (4), p.589-598

1999

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Nucleotide Binding by the HIV-1 Integrase Protein In Vitro

Journal of acquired immune deficiency syndromes (1999), 1994-12, Vol.7 (12), p.1215-1223

1994

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Translation control of the immune checkpoint in cancer and its therapeutic targeting

Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

Serum interleukin-4 is elevated in clinical drug-induced liver injury

Antibiotic Allergy Labels in a Liver Transplant Recipient Study

Epidemiology and outcomes of primary sclerosing cholangitis: an Australian multicentre retrospective cohort study

Structure-Assisted Design of Mechanism-Based Irreversible Inhibitors of Human Rhinovirus 3C Protease with Potent Antiviral Activity against Multiple Rhinovirus Serotypes

In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P1 Lactam Moieties as l-Glutamine Replacements

Inhibition of Human Rhinovirus-Induced Cytokine Production by AG7088, a Human Rhinovirus 3C Protease Inhibitor

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Effects of different Rht-B1b, Rht-D1b and Rht-B1c dwarfing genes on agronomic characteristics in wheat

Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae

Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure–Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics

Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation

Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease

Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors

Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides

Nucleotide Binding by the HIV-1 Integrase Protein In Vitro

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