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Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (32), p.12982-12987

2007

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Targeted in vivo delivery of siRNA and an endosome-releasing agent to hepatocytes

Methods in molecular biology (Clifton, N.J.), 2015-01, Vol.1218, p.163

2015

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Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules

The journal of gene medicine, 2006-07, Vol.8 (7), p.852-873

2006

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HIF2 Inactivation and Tumor Suppression with a Tumor-Directed RNA-Silencing Drug in Mice and Humans

Clinical cancer research, 2022-12, Vol.28 (24), p.5405-5418

2022

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Co-injection of a targeted, reversibly masked endosomolytic polymer dramatically improves the efficacy of cholesterol-conjugated small interfering RNAs in vivo

Nucleic acid therapeutics, 2012-12, Vol.22 (6), p.380

2012

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HIF2α-Targeted RNAi Therapeutic Inhibits Clear Cell Renal Cell Carcinoma

Molecular cancer therapeutics, 2018-01, Vol.17 (1), p.140-149

2018

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Isolation of Human cDNAs That Restore Methotrexate Sensitivity and Reduced Folate Carrier Activity in Methotrexate Transport-defective Chinese Hamster Ovary Cells

The Journal of biological chemistry, 1995-07, Vol.270 (29), p.17468-17475

1995

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Protease-triggered siRNA delivery vehicles

Journal of controlled release, 2015-07, Vol.209, p.57-66

2015

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Abstract 4775: Optimizing the potency and dosing design for ARO-HIF2: An RNAi therapeutic for clear cell renal cell carcinoma

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4775-4775

2019

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Impaired Membrane Transport in Methotrexate-resistant CCRF-CEM Cells Involves Early Translation Termination and Increased Turnover of a Mutant Reduced Folate Carrier

The Journal of biological chemistry, 1999-04, Vol.274 (15), p.10388-10394

1999

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In Vivo Selection and Validation of Liver-Specific Ligands Using a New T7 Phage Peptide Display System

Drug delivery, 2007-08, Vol.14 (6), p.357-369

2007

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Hepatocyte Targeting of Nucleic Acid Complexes and Liposomes by a T7 Phage p17 Peptide

Molecular pharmaceutics, 2006-07, Vol.3 (4), p.386-397

2006

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Structure and organization of the human reduced folate carrier gene

Biochimica et biophysica acta, 1998-11, Vol.1442 (2), p.389-393

1998

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Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier

Biochimica et biophysica acta, 1998-10, Vol.1375 (1), p.6-12

1998

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A new peptide ligand that targets particles and heterologous proteins to hepatocytes in vivo

Molecular therapy, 2003-12, Vol.8 (6), p.867-872

2003

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Gene Amplification and Increased Expression of the Reduced Folate Carrier in Transport Elevated K562 Cells

Biochemical pharmacology, 1998-04, Vol.55 (7), p.1135-1138

1998

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Personalized Medicine for Dyslipidemias by RNA Interference-Mediated Reductions in Apolipoprotein C3 or Angiopoietin-Like Protein 3

Journal of clinical lipidology, 2019-05, Vol.13 (3), p.e15-e15

2019

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Nano-Bio- Electronic, Photonic and MEMS Packaging

2nd ed. 2021., 2021

Volltextzugriff (PDF)

Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy

Clinical cancer research, 1998-09, Vol.4 (9), p.2169-2177

1998

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Abstract 16554: RNA Interference Mediated Apolipoprotein C3 Gene Silencing as a Therapeutic for Hypertriglyceridemia

Circulation (New York, N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A16554-A16554

2018

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Abstract 16336: Development of an RNA Interference Therapeutic Targeting Angiopoietin-Like Protein 3 for Treatment of Hyperlipidemia

Circulation (New York, N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A16336-A16336

2018

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Innovation and Change in English Language Education

1, 2013

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Transesophageal Echocardiography for Pediatric and Congenital Heart Disease

2nd ed. 2021., 2021

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Decision Tree-Based Maneuver Prediction for Driver Rear-End Risk-Avoidance Behaviors in Cut-In Scenarios

Journal of advanced transportation, 2017-01, Vol.2017, p.1-12

2017

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Integrated Optimization of Bus Line Fare and Operational Strategies Using Elastic Demand

Journal of advanced transportation, 2017-01, Vol.2017, p.1-15

2017

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