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Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines

Redox biology, 2020-10, Vol.37, p.101722-101722, Article 101722

2020

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The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

Redox biology, 2020-01, Vol.28, p.101341, Article 101341

2020

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Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

The Journal of biological chemistry, 2017-10, Vol.292 (41), p.16804-16809

2017

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Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts

Free radical biology & medicine, 2019-01, Vol.130, p.140-150

2019

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β-sitosterol protects against carbon tetrachloride hepatotoxicity but not gentamicin nephrotoxicity in rats via the induction of mitochondrial glutathione redox cycling

Molecules (Basel, Switzerland), 2014-10, Vol.19 (11), p.17649-17662

2014

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Not just a cousin of the naked mole-rat: Damaraland mole-rats offer unique insights into biomedicine

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2022-10, Vol.262, p.110772-110772, Article 110772

2022

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Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

Biochemical Society transactions, 2019-10, Vol.47 (5), p.1461-1469

2019

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S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I

Free radical biology & medicine, 2019-11, Vol.143, p.545-559

2019

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Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

Free radical biology & medicine, 2021-02, Vol.164, p.223-232

2021

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Measurement of Proton Leak in Isolated Mitochondria

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1782, p.157

2018

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Suppression of superoxide/hydrogen peroxide production at mitochondrial site IQ decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet

Free radical biology & medicine, 2023-08, Vol.204, p.276-286

2023

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Ursolic acid induces mitochondrial biogenesis through the activation of AMPK and PGC-1 in C2C12 myotubes: a possible mechanism underlying its beneficial effect on exercise endurance

Food & function, 2017-07, Vol.8 (7), p.2425-2436

2017

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Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1782, p.287

2018

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Plate-Based Measurement of Respiration by Isolated Mitochondria

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1782, p.301

2018

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Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response

PloS one, 2016-05, Vol.11 (5), p.e0155879-e0155879

2016

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Herba Cistanches stimulates cellular glutathione redox cycling by reactive oxygen species generated from mitochondrial respiration in H9c2 cardiomyocytes

Pharmaceutical biology, 2013-01, Vol.51 (1), p.64-73

2013

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β-Sitosterol increases mitochondrial electron transport by fluidizing mitochondrial membranes and enhances mitochondrial responsiveness to increasing energy demand by the induction of uncoupling in C2C12 myotubes

Journal of functional foods, 2016-05, Vol.23, p.253-260

2016

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Are mitochondria the main contributor of reactive oxygen species in cells?

Journal of experimental biology, 2021-03, Vol.224 (Pt 5)

2021

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An ursolic acid-enriched extract of Cynomorium songaricum protects against carbon tetrachloride hepatotoxicity and gentamicin nephrotoxicity in rats possibly through a mitochondrial pathway: A comparison with ursolic acid

Journal of functional foods, 2014-03, Vol.7, p.330-341

2014

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An ursolic acid-enriched Cynomorium songarium extract attenuates high fat diet-induced obesity in mice possibly through mitochondrial uncoupling

Journal of functional foods, 2014-07, Vol.9, p.211-224

2014

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Cistanches Herba reduces the weight gain in high fat diet-induced obese mice possibly through mitochondrial uncoupling

Journal of functional foods, 2014-09, Vol.10, p.292-304

2014

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S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site I Q without inhibiting reverse electron flow through Complex I

Free radical biology & medicine, 2019-11, Vol.143, p.545

2019

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Absolute Potassium Cation Affinities (PCAs) in the Gas Phase

Chemistry : a European journal, 2003-07, Vol.9 (14), p.3383-3396

2003

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39 - Functional Characterization of S1QELs

Free radical biology & medicine, 2016-11, Vol.100, p.S31-S32

2016

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Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts

β-sitosterol protects against carbon tetrachloride hepatotoxicity but not gentamicin nephrotoxicity in rats via the induction of mitochondrial glutathione redox cycling

Not just a cousin of the naked mole-rat: Damaraland mole-rats offer unique insights into biomedicine

Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I

Senescent cells promote tissue NAD + decline during ageing via the activation of CD38 + macrophages

Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

Measurement of Proton Leak in Isolated Mitochondria

Suppression of superoxide/hydrogen peroxide production at mitochondrial site IQ decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet

Ursolic acid induces mitochondrial biogenesis through the activation of AMPK and PGC-1 in C2C12 myotubes: a possible mechanism underlying its beneficial effect on exercise endurance

Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria

Plate-Based Measurement of Respiration by Isolated Mitochondria

Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response

Herba Cistanches stimulates cellular glutathione redox cycling by reactive oxygen species generated from mitochondrial respiration in H9c2 cardiomyocytes

β-Sitosterol increases mitochondrial electron transport by fluidizing mitochondrial membranes and enhances mitochondrial responsiveness to increasing energy demand by the induction of uncoupling in C2C12 myotubes

Are mitochondria the main contributor of reactive oxygen species in cells?

An ursolic acid-enriched extract of Cynomorium songaricum protects against carbon tetrachloride hepatotoxicity and gentamicin nephrotoxicity in rats possibly through a mitochondrial pathway: A comparison with ursolic acid

An ursolic acid-enriched Cynomorium songarium extract attenuates high fat diet-induced obesity in mice possibly through mitochondrial uncoupling

Cistanches Herba reduces the weight gain in high fat diet-induced obese mice possibly through mitochondrial uncoupling

S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site I Q without inhibiting reverse electron flow through Complex I

Absolute Potassium Cation Affinities (PCAs) in the Gas Phase

39 - Functional Characterization of S1QELs

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