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Hdmx Modulates the Outcome of P53 Activation in Human Tumor Cells

The Journal of biological chemistry, 2006-11, Vol.281 (44), p.33036-33044

2006

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A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time

Cell reports (Cambridge), 2014-12, Vol.9 (5), p.1946-1958

2014

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Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke

Computational and structural biotechnology journal, 2020-01, Vol.18, p.1056-1073

2020

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NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling

Cell reports (Cambridge), 2014-06, Vol.7 (6), p.1876-1886

2014

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The Hepatitis B Virus X Protein Sensitizes HepG2 Cells to UV Light-induced DNA Damage

The Journal of biological chemistry, 2005-09, Vol.280 (39), p.33525-33535

2005

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Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE−/− mouse model

Journal of applied toxicology, 2021-10, Vol.41 (10), p.1598-1619

2021

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Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5‐week study in A/J mice

Journal of applied toxicology, 2022-10, Vol.42 (10), p.1701-1722

2022

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Bruton's Tyrosine Kinase Separately Regulates NFκB p65RelA Activation and Cytokine Interleukin (IL)-10/IL-12 Production in TLR9-stimulated B Cells

The Journal of biological chemistry, 2008-04, Vol.283 (17), p.11189-11198

2008

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The POPX2 phosphatase regulates cancer cell motility and invasiveness

Cell cycle (Georgetown, Tex.), 2010-01, Vol.9 (1), p.179-187

2010

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Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case

Toxicology reports, 2020-01, Vol.7, p.1187-1206

2020

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Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases: Overview of Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine

1, 2018

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Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange

Nucleic acids research, 2005-01, Vol.33 (17), p.e147

2005

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ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress

Molecular cell, 2010-10, Vol.40 (1), p.75-86

2010

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Therapeutic strategies for hepatitis B virus-associated hepatocellular carcinoma

Current drug targets, 2002-10, Vol.3 (5), p.369

2002

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A Membrane Protein Enriched in Endoplasmic Reticulum Exit Sites Interacts with COPII

The Journal of biological chemistry, 2001-10, Vol.276 (43), p.40008-40017

2001

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A 6-month systems toxicology inhalation study in ApoE -/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke

American journal of physiology. Heart and circulatory physiology, 2020-03, Vol.318 (3), p.H604-H631

2020

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Deconvolution of Systemic Pharmacokinetics Predicts Inhaled Aerosol Dosimetry of Nicotine

European journal of pharmaceutical sciences, 2023-01, Vol.180, p.106321, Article 106321

2023

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Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke

Toxicological sciences, 2020-11, Vol.178 (1), p.44-70

2020

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Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke

Regulatory toxicology and pharmacology, 2016-11, Vol.81, p.S59-S81

2016

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WIP1 phosphatase is a negative regulator of NF-κB signalling

Nature cell biology, 2009-05, Vol.11 (5), p.659-666

2009

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Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice

Toxicological sciences, 2020-11, Vol.178 (1), p.138-158

2020

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Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke

Regulatory toxicology and pharmacology, 2016-11, Vol.81, p.S82-S92

2016

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E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse model

Archives of toxicology, 2020-06, Vol.94 (6), p.2163-2177

2020

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Quantitative analyses reveal the importance of regulated Hdmx degradation for P53 activation

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12365-12370

2007

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Hdmx Modulates the Outcome of P53 Activation in Human Tumor Cells

A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time

Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke

NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling

The Hepatitis B Virus X Protein Sensitizes HepG2 Cells to UV Light-induced DNA Damage

Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE−/− mouse model

Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5‐week study in A/J mice

Bruton's Tyrosine Kinase Separately Regulates NFκB p65RelA Activation and Cytokine Interleukin (IL)-10/IL-12 Production in TLR9-stimulated B Cells

The POPX2 phosphatase regulates cancer cell motility and invasiveness

Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case

Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases: Overview of Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine

Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange

ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress

Therapeutic strategies for hepatitis B virus-associated hepatocellular carcinoma

A Membrane Protein Enriched in Endoplasmic Reticulum Exit Sites Interacts with COPII

A 6-month systems toxicology inhalation study in ApoE -/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke

Deconvolution of Systemic Pharmacokinetics Predicts Inhaled Aerosol Dosimetry of Nicotine

Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke

Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke

WIP1 phosphatase is a negative regulator of NF-κB signalling

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice

Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke

E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse model

A 6-month inhalation toxicology study in Apoe−/− mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract

Quantitative analyses reveal the importance of regulated Hdmx degradation for P53 activation

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