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Mechanism of eIF6 release from the nascent 60S ribosomal subunit

Nature structural & molecular biology, 2015-11, Vol.22 (11), p.914-919

2015

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Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

Nature communications, 2021-04, Vol.12 (1), p.2482-20, Article 2482

2021

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Defective ribosome assembly in Shwachman-Diamond syndrome

Blood, 2011-10, Vol.118 (16), p.4305-4312

2011

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eIF6 rebinding dynamically couples ribosome maturation and translation

Nature communications, 2022-03, Vol.13 (1), p.1562-1562, Article 1562

2022

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A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development

American journal of human genetics, 2019-05, Vol.104 (5), p.985-989

2019

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Inactivating CUX1 mutations promote tumorigenesis

Nature genetics, 2014-01, Vol.46 (1), p.33-38

2014

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The utility of transposon mutagenesis for cancer studies in the era of genome editing

Genome Biology, 2015-10, Vol.16 (1), p.229, Article 229

2015

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The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast

Nature genetics, 2007-04, Vol.39 (4), p.486-495

2007

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Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen

The Journal of pharmacology and experimental therapeutics, 2014-10, Vol.351 (1), p.61-66

2014

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Phospho-aspirin-2 (MDC-22) inhibits estrogen receptor positive breast cancer growth both in vitro and in vivo by a redox-dependent effect

PloS one, 2014-11, Vol.9 (11), p.e111720

2014

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Population-based analysis of POT1 variants in a cutaneous melanoma case–control cohort

Journal of medical genetics, 2023-07, Vol.60 (7), p.692-696

2023

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Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

JAMA dermatology (Chicago, Ill.), 2019-05, Vol.155 (5), p.604

2019

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Phospho-NSAIDs Have Enhanced Efficacy in Mice Lacking Plasma Carboxylesterase: Implications for their Clinical Pharmacology

Pharmaceutical research, 2015-05, Vol.32 (5), p.1663-1675

2015

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Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate

International journal of oncology, 2014-02, Vol.44 (2), p.521-529

2014

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Comparative in vitro metabolism of phospho-tyrosol-indomethacin by mice, rats and humans

Biochemical pharmacology, 2013-04, Vol.85 (8), p.1195-1202

2013

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Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics

International journal of oncology, 2013-09, Vol.43 (3), p.895-902

2013

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A novel ibuprofen derivative with anti-lung cancer properties: Synthesis, formulation, pharmacokinetic and efficacy studies

International journal of pharmaceutics, 2014-12, Vol.477 (1-2), p.236-243

2014

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Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity

The Journal of pharmacology and experimental therapeutics, 2012-02, Vol.340 (2), p.422-432

2012

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Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress

BMC cancer, 2014-02, Vol.14 (1), p.141-141, Article 141

2014

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Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters

Molecular nutrition & food research, 2011-07, Vol.55 (7), p.979-988

2011

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Therapy for mitochondrial genetic disease: are we at the thin end of the wedge?

Reproductive biomedicine online, 2014-08, Vol.29 (2), p.147-149

2014

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The anticancer effect of phospho-tyrosol-indomethacin (MPI-621), a novel phosphoderivative of indomethacin: in vitro and in vivo studies

Carcinogenesis (New York), 2013-04, Vol.34 (4), p.943-951

2013

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Aerosol administration of phospho-sulindac inhibits lung tumorigenesis

Molecular cancer therapeutics, 2013-08, Vol.12 (8), p.1417-1428

2013

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Regioselective oxidation of phospho‐NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety

British journal of pharmacology, 2012-09, Vol.167 (1), p.222-232

2012

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In Vitro and In Vivo Metabolic Studies of Phospho-aspirin (MDC-22)

Pharmaceutical research, 2012-12, Vol.29 (12), p.3292-3301

2012

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Mechanism of eIF6 release from the nascent 60S ribosomal subunit

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

Defective ribosome assembly in Shwachman-Diamond syndrome

eIF6 rebinding dynamically couples ribosome maturation and translation

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development

Inactivating CUX1 mutations promote tumorigenesis

The utility of transposon mutagenesis for cancer studies in the era of genome editing

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast

Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen

Phospho-aspirin-2 (MDC-22) inhibits estrogen receptor positive breast cancer growth both in vitro and in vivo by a redox-dependent effect

Population-based analysis of POT1 variants in a cutaneous melanoma case–control cohort

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

Phospho-NSAIDs Have Enhanced Efficacy in Mice Lacking Plasma Carboxylesterase: Implications for their Clinical Pharmacology

Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate

Comparative in vitro metabolism of phospho-tyrosol-indomethacin by mice, rats and humans

Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics

A novel ibuprofen derivative with anti-lung cancer properties: Synthesis, formulation, pharmacokinetic and efficacy studies

Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity

Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress

Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters

Therapy for mitochondrial genetic disease: are we at the thin end of the wedge?

The anticancer effect of phospho-tyrosol-indomethacin (MPI-621), a novel phosphoderivative of indomethacin: in vitro and in vivo studies

Aerosol administration of phospho-sulindac inhibits lung tumorigenesis

Regioselective oxidation of phospho‐NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety

In Vitro and In Vivo Metabolic Studies of Phospho-aspirin (MDC-22)

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