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An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-Pyrrolidines

Journal of organic chemistry, 2014-08, Vol.79 (15), p.7152-7161

2014

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BACE1 inhibitors: A head group scan on a series of amides

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (14), p.4239-4243

2013

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Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Angewandte Chemie (International ed.), 2012-10, Vol.51 (40), p.10169-10172

International ed. in English, 2012

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Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

Heterocycles, 2014, Vol.88 (2), p.1079

2014

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Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors

Journal of medicinal chemistry, 2020-09, Vol.63 (18), p.10287-10306

2020

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β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.3980-3995

2013

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Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactions

Chemical communications (Cambridge, England), 2013-04, Vol.49 (29), p.2989-2991

2013

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Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (23), p.6969-6974

2010

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Asymmetric Synthesis and Receptor Pharmacology of the Group II mGlu Receptor Ligand (1S,2R,3R,5R,6S)-2-Amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid-HYDIA

ChemMedChem, 2008-02, Vol.3 (2), p.323-335

2008

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Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Angewandte Chemie, 2012-10, Vol.124 (40), p.10316-10319

2012

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Enantioselective functionalisation of the C-2' position of 1,2,3,4,5-pentamethylazaferrocene via sparteine mediated lithiation: potential new ligands for asymmetric catalysis

Organic & biomolecular chemistry, 2008-01, Vol.6 (2), p.330-339

2008

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Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: New potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1

Bioorganic & medicinal chemistry letters, 2007-12, Vol.17 (24), p.6811-6815

2007

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Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1091-1095

2008

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Mutagenesis and molecular modeling of the orthosteric binding site of the mGlu2 receptor determining interactions of the group II receptor antagonist (3)H-HYDIA

ChemMedChem, 2009-07, Vol.4 (7), p.1086

2009

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Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2725-2729

2008

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Enantioselective functionalisation of the C-2′ position of 1,2,3,4,5-pentamethylazaferroceneviasparteine mediated lithiation: potential new ligands for asymmetric catalysis

Organic & biomolecular chemistry, 2008, Vol.6 (2), p.330-339

2008

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Mutagenesis and Molecular Modeling of the Orthosteric Binding Site of the mGlu2 Receptor Determining Interactions of the Group II Receptor Antagonist 3H-HYDIA

ChemMedChem, 2009-07, Vol.4 (7), p.1086-1094

2009

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Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Angewandte Chemie, 2012-10, Vol.124 (40), p.10316-10319

2012

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Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides

Bioorganic & medicinal chemistry, 1999-05, Vol.7 (5), p.773-788

1999

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Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactionsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3cc40757h

2013-03

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Design and synthesis of C-linked fucosides as inhibitors of E-selectin

Bioorganic & medicinal chemistry, 1996-07, Vol.4 (7), p.1149-1165

1996

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ChemInform Abstract: An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-pyrrolidines

ChemInform, 2015-02, Vol.46 (5), p.no-no

2015

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A Highly Efficient Synthesis Route for the Rapid Generation of 1,2,5,6-Tetrasubstituted Benzimidazoles

Synlett, 2008-06, Vol.2008 (10), p.1467-1470

2008

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ChemInform Abstract: Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

ChemInform, 2014-06, Vol.45 (23), p.no-no

2014

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ChemInform Abstract: Conformationally Restricted Pyrrolidines by Intramolecular [2 + 2] Photocycloaddition Reactions

ChemInform, 2013-07, Vol.44 (29), p.no-no

2013

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An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-Pyrrolidines

BACE1 inhibitors: A head group scan on a series of amides

Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors

β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactions

Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists

Asymmetric Synthesis and Receptor Pharmacology of the Group II mGlu Receptor Ligand (1S,2R,3R,5R,6S)-2-Amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid-HYDIA

Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Enantioselective functionalisation of the C-2' position of 1,2,3,4,5-pentamethylazaferrocene via sparteine mediated lithiation: potential new ligands for asymmetric catalysis

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: New potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

Mutagenesis and molecular modeling of the orthosteric binding site of the mGlu2 receptor determining interactions of the group II receptor antagonist (3)H-HYDIA

Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

Enantioselective functionalisation of the C-2′ position of 1,2,3,4,5-pentamethylazaferroceneviasparteine mediated lithiation: potential new ligands for asymmetric catalysis

Mutagenesis and Molecular Modeling of the Orthosteric Binding Site of the mGlu2 Receptor Determining Interactions of the Group II Receptor Antagonist 3H-HYDIA

Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides

Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactionsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3cc40757h

Design and synthesis of C-linked fucosides as inhibitors of E-selectin

ChemInform Abstract: An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-pyrrolidines

A Highly Efficient Synthesis Route for the Rapid Generation of 1,2,5,6-Tetrasubstituted Benzimidazoles

ChemInform Abstract: Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

ChemInform Abstract: Conformationally Restricted Pyrrolidines by Intramolecular [2 + 2] Photocycloaddition Reactions

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