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Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling

Molecular cell, 2016-05, Vol.62 (3), p.385-396

2016

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The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division

Science signaling, 2018-01, Vol.11 (511)

2018

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Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis

Open biology, 2021-10, Vol.11 (10), p.210033-210033

2021

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Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

eLife, 2018-04, Vol.7

2018

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DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation

Molecular and Cellular Biology, 2013-10, Vol.33 (19), p.3864-3878

2013

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PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation

Molecular and Cellular Biology, 2012-06, Vol.32 (12), p.2268-2278

2012

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Wnt5a Control of Cell Polarity and Directional Movement by Polarized Redistribution of Adhesion Receptors

Science (American Association for the Advancement of Science), 2008-04, Vol.320 (5874), p.365-369

2008

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Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior

The Journal of biological chemistry, 2015-06, Vol.290 (25), p.15707-15716

2015

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Wnt5a Directs Polarized Calcium Gradients by Recruiting Cortical Endoplasmic Reticulum to the Cell Trailing Edge

Developmental cell, 2013-09, Vol.26 (6), p.645-657

2013

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Spontaneous Cell Competition in Immortalized Mammalian Cell Lines

PloS one, 2015-07, Vol.10 (7), p.e0132437-e0132437

2015

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Menin localization in cell membrane compartment

Cancer biology & therapy, 2016-01, Vol.17 (1), p.114-122

2016

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Mapping protein post-translational modifications with mass spectrometry

Nature methods, 2007-10, Vol.4 (10), p.798-806

2007

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Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis

Science signaling, 2020-03, Vol.13 (621)

2020

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Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras

Biochemical and biophysical research communications, 2017-11, Vol.493 (1), p.213-219

2017

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A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme

Molecular & cellular proteomics, 2009-10, Vol.8 (10), p.2308-2320

2009

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Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma

Molecular cell, 2009-04, Vol.34 (1), p.115-131

2009

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Wnt-Dependent Control of Cell Polarity in Cultured Cells

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1481, p.61

2016

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Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response

Molecular pharmacology, 2013-03, Vol.83 (3), p.594-604

2013

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Suppression of CED-3-independent apoptosis by mitochondrial βNAC in Caenorhabditis elegans

Nature, 2003-08, Vol.424 (6952), p.1066-1071

2003

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C. elegans pur alpha, an activator of end-1, synergizes with the Wnt pathway to specify endoderm

Developmental biology, 2009-03, Vol.327 (1), p.12-23

2009

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Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans

Nature (London), 2003-08, Vol.424 (6952), p.1066-1071

2003

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Chemical probe mediated visualization of protein S-palmitoylation in patient tissue samples

Frontiers in physiology, 2023-02, Vol.14, p.1063247-1063247

2023

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Acute Regulation of Habituation Learning via Posttranslational Palmitoylation

Current biology, 2020-07, Vol.30 (14), p.2729-2738.e4

2020

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A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles

Cancer discovery, 2017-11, Vol.7 (11), p.1266-1283

2017

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Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling

The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division

Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis

Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation

PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation

Wnt5a Control of Cell Polarity and Directional Movement by Polarized Redistribution of Adhesion Receptors

Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior

Wnt5a Directs Polarized Calcium Gradients by Recruiting Cortical Endoplasmic Reticulum to the Cell Trailing Edge

Spontaneous Cell Competition in Immortalized Mammalian Cell Lines

Menin localization in cell membrane compartment

A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype

Mapping protein post-translational modifications with mass spectrometry

Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis

Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras

A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme

Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma

Wnt-Dependent Control of Cell Polarity in Cultured Cells

Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response

Suppression of CED-3-independent apoptosis by mitochondrial βNAC in Caenorhabditis elegans

C. elegans pur alpha, an activator of end-1, synergizes with the Wnt pathway to specify endoderm

Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans

Chemical probe mediated visualization of protein S-palmitoylation in patient tissue samples

Acute Regulation of Habituation Learning via Posttranslational Palmitoylation

A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles

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