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The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

PLoS pathogens, 2018-09, Vol.14 (9), p.e1007315

2018

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Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

PLoS pathogens, 2020-11, Vol.16 (11), p.e1008932-e1008932

2020

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Athenaeus describes the most ancient intellectual property

Prometheus (Saint Lucia, Brisbane, Qld.), 2017-04, Vol.35 (2), p.137-143

Witty, Michael

2017

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Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

Science translational medicine, 2017-04, Vol.9 (387)

2017

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3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3479-3487

2012

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Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum

Malaria journal, 2013-11, Vol.12 (1), p.424-424, Article 424

2013

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Transformation of struvite from wastewater to a hydrogen fuel storage compound ammonia borane

Frontiers in chemistry, 2023-11, Vol.11, p.1269845-1269845

2023

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Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (1), p.6-10

2018

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UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Antimicrobial agents and chemotherapy, 2018-09, Vol.62 (9)

2018

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Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis

Journal of medicinal chemistry, 2022-04, Vol.65 (7), p.5606-5624

2022

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Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 1

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2789-2798

2014

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Novel Orally Active Antimalarial Thiazoles

Journal of medicinal chemistry, 2011-11, Vol.54 (21), p.7713-7719

2011

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Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 2

Journal of medicinal chemistry, 2014-11, Vol.57 (21), p.8839-8848

2014

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Cell-based medicinal chemistry optimization of high throughput screening hits for orally active antimalarials. Part 2: hits from SoftFocus kinase and other libraries

Journal of medicinal chemistry, 2013-10, Vol.56 (20), p.7750-7754

2013

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Mission possible

Nature (London), 2007-09, Vol.449 (7159), p.166-169

2007

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Structure–Activity-Relationship Studies around the 2‑Amino Group and Pyridine Core of Antimalarial 3,5-Diarylaminopyridines Lead to a Novel Series of Pyrazine Analogues with Oral in Vivo Activity

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8860-8871

2013

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Structure–Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7572-7579

2015

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2,4-Diaminothienopyrimidines as Orally Active Antimalarial Agents

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.1014-1022

2014

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Antimalarial aminothiazoles and aminopyridines from phenotypic whole-cell screening of a SoftFocus(®) library

Future medicinal chemistry, 2012-12, Vol.4 (18), p.2265-2277

2012

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Structure–Activity Relationship Studies of Orally Active Antimalarial 3,5-Substituted 2‑Aminopyridines

Journal of medicinal chemistry, 2012-12, Vol.55 (24), p.11022-11030

2012

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Cell-Based Medicinal Chemistry Optimization of High Throughput Screening Hits for Orally Active Antimalarials. Part 2: Hits from SoftFocus Kinase and other Libraries: Miniperspectives Series on Phenotypic Screening for Antiinfective Targets

Journal of medicinal chemistry, 2013-10, Vol.56 (20), p.7750-7754

2013

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Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria"

Antimicrobial agents and chemotherapy, 2018-11, Vol.62 (11)

2018

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The Deipnosophists and Dr Johnson

Lexicographica, 2020-11, Vol.36 (1), p.311-324

Witty, Michael

2020

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The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

Athenaeus describes the most ancient intellectual property

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential

Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum

Transformation of struvite from wastewater to a hydrogen fuel storage compound ammonia borane

Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis

Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 1

Identification of a Potential Antimalarial Drug Candidate from a Series of 2‑Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle

Novel Orally Active Antimalarial Thiazoles

Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 2

Cell-based medicinal chemistry optimization of high throughput screening hits for orally active antimalarials. Part 2: hits from SoftFocus kinase and other libraries

A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum -Infected Mouse Models from Structure–Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines

Mission possible

Structure–Activity-Relationship Studies around the 2‑Amino Group and Pyridine Core of Antimalarial 3,5-Diarylaminopyridines Lead to a Novel Series of Pyrazine Analogues with Oral in Vivo Activity

Structure–Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines

2,4-Diaminothienopyrimidines as Orally Active Antimalarial Agents

Antimalarial aminothiazoles and aminopyridines from phenotypic whole-cell screening of a SoftFocus(®) library

Structure–Activity Relationship Studies of Orally Active Antimalarial 3,5-Substituted 2‑Aminopyridines

Cell-Based Medicinal Chemistry Optimization of High Throughput Screening Hits for Orally Active Antimalarials. Part 2: Hits from SoftFocus Kinase and other Libraries: Miniperspectives Series on Phenotypic Screening for Antiinfective Targets

Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria"

The Deipnosophists and Dr Johnson

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