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Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.890-899

2018

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Renal Transporters in Drug Development

Annual review of pharmacology and toxicology, 2013-01, Vol.53 (1), p.503-529

2013

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Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance

Clinical pharmacology and therapeutics, 2022-09, Vol.112 (3), p.485-500

2022

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Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.781-795

2013

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Involvement of CB1 and CB2 receptors in neuroprotective effects of cannabinoids in experimental TDP-43 related frontotemporal dementia using male mice

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116473-116473, Article 116473

2024

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The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

Clinical pharmacokinetics, 2016-06, Vol.55 (6), p.711-721

2016

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Fundamental aspects of DMPK optimization of targeted protein degraders

Drug discovery today, 2020-06, Vol.25 (6), p.969-982

2020

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Targeted protein degraders: a call for collective action to advance safety assessment

Nature reviews. Drug discovery, 2022-06, Vol.21 (6), p.401-402

2022

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pKa determination by 1H NMR spectroscopy – An old methodology revisited

Journal of pharmaceutical and biomedical analysis, 2014-05, Vol.93, p.147-155

2014

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ITC Commentary on Metformin Clinical Drug–Drug Interaction Study Design That Enables an Efficacy‐ and Safety‐Based Dose Adjustment Decision

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.781-784

2018

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Involvement of CB 1 and CB 2 receptors in neuroprotective effects of cannabinoids in experimental TDP-43 related frontotemporal dementia using male mice

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116473

2024

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Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain

European journal of medicinal chemistry, 2022-12, Vol.243, p.114750-114750, Article 114750

2022

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Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold

Nuclear medicine and biology, 2022-05, Vol.108-109, p.24-32

2022

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Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter OATP2B1

Journal of chemical information and modeling, 2017-06, Vol.57 (6), p.1402-1413

2017

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High Selectivity of the γ-Aminobutyric Acid Transporter 2 (GAT-2, SLC6A13) Revealed by Structure-based Approach

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.37745-37756

2012

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Chemical Development of Intracellular Protein Heterodimerizers

Chemistry & biology, 2013-04, Vol.20 (4), p.549-557

2013

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A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence

Nature communications, 2023-12, Vol.14 (1), p.8039-8039, Article 8039

2023

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Diagnostic challenges within the Bacillus cereus-group: finding the beast without teeth

New microbes and new infections, 2022-11, Vol.49-50, p.101040-101040, Article 101040

2022

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Risky Decisions in a Lottery Task Are Associated with an Increase of Cocaine Use

Frontiers in psychology, 2016, Vol.7, p.640-640

2016

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Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy

Journal of medical genetics, 2011-02, Vol.48 (2), p.105-116

2011

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Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes

Physiological genomics, 2003-10, Vol.15 (2), p.148-157

2003

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Whole-Genome Assemblies of 16 Burkholderia pseudomallei Isolates from Rivers in Laos

Microbiology resource announcements, 2021-01, Vol.10 (4), p.e01226-20

2021

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Gene expression in cortex and hippocampus during acute pneumococcal meningitis

BMC biology, 2006-06, Vol.4 (1), p.15-15, Article 15

2006

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Exploring Context from the Consumer Perspective: Insights from eBusiness and Health Care

Business Information Systems Workshops, p.340-346

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Social Media Analytics Using Business Intelligence and Social Media Tools – Differences and Implications

Business Information Systems Workshops, p.252-259

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Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Renal Transporters in Drug Development

Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance

Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling

Involvement of CB1 and CB2 receptors in neuroprotective effects of cannabinoids in experimental TDP-43 related frontotemporal dementia using male mice

The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

Fundamental aspects of DMPK optimization of targeted protein degraders

Targeted protein degraders: a call for collective action to advance safety assessment

pKa determination by 1H NMR spectroscopy – An old methodology revisited

ITC Commentary on Metformin Clinical Drug–Drug Interaction Study Design That Enables an Efficacy‐ and Safety‐Based Dose Adjustment Decision

Involvement of CB 1 and CB 2 receptors in neuroprotective effects of cannabinoids in experimental TDP-43 related frontotemporal dementia using male mice

Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain

Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold

Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter OATP2B1

High Selectivity of the γ-Aminobutyric Acid Transporter 2 (GAT-2, SLC6A13) Revealed by Structure-based Approach

Chemical Development of Intracellular Protein Heterodimerizers

A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence

Diagnostic challenges within the Bacillus cereus-group: finding the beast without teeth

Risky Decisions in a Lottery Task Are Associated with an Increase of Cocaine Use

Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy

Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes

Whole-Genome Assemblies of 16 Burkholderia pseudomallei Isolates from Rivers in Laos

Gene expression in cortex and hippocampus during acute pneumococcal meningitis

Exploring Context from the Consumer Perspective: Insights from eBusiness and Health Care

Social Media Analytics Using Business Intelligence and Social Media Tools – Differences and Implications

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