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Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)

Bioorganic & medicinal chemistry, 2008-01, Vol.18 (2), p.726-731

2008

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A Divergent Approach to the Synthesis of 3-Substituted-2-pyrazolines: Suzuki Cross-Coupling of 3-Sulfonyloxy-2-pyrazolines

Journal of organic chemistry, 2009-08, Vol.74 (16), p.6390-6393

2009

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Histone Deacetylase Inhibitors

Journal of medicinal chemistry, 2003-11, Vol.46 (24), p.5097-5116

2003

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A New Strategy for the Synthesis of Benzylic Sulfonamides: Palladium-Catalyzed Arylation and Sulfonamide Metathesis

Journal of organic chemistry, 2007-10, Vol.72 (21), p.8135-8138

2007

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Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor

The Journal of pharmacology and experimental therapeutics, 2017-05, Vol.361 (2), p.229-244

2017

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Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (7), p.2053-2058

2009

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Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.973-978

2008

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Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue

Journal of the American Chemical Society, 2000-11, Vol.122 (46), p.11519-11520

2000

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Aminosuberoyl hydroxamic acids (ASHAs): A potent new class of HDAC inhibitors

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (14), p.3969-3971

2007

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Bioorganic & medicinal chemistry letters, 2008-03, Vol.18 (6), p.1859-1863

2008

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Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor

ACS medicinal chemistry letters, 2014-04, Vol.5 (4), p.340-345

2014

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Benzo[b]thiophene-based histone deacetylase inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (16), p.4562-4567

2007

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Design of novel histone deacetylase inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (16), p.4619-4624

2007

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1859-1863

2008

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Revision of the biosynthetic origin of oxygens in mevinolin (lovastatin), a hypocholesterolemic drug from Aspergillus terreus MF 4845

Journal of the American Chemical Society, 1994-03, Vol.116 (6), p.2693-2694

1994

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Putative Diels−Alder-Catalyzed Cyclization during the Biosynthesis of Lovastatin

Journal of organic chemistry, 1996-04, Vol.61 (8), p.2613-2623

1996

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Yeast Geranylgeranyltransferase Type-II: Steady State Kinetic Studies of the Recombinant Enzyme

Biochemistry (Easton), 1996-08, Vol.35 (32), p.10454-10463

1996

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Suppression of racemization in the carbonylation of amino acid-derived aryl triflates

Tetrahedron letters, 2007-06, Vol.48 (26), p.4509-4513

2007

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Garden music

Witter, David J

2012

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Novel phosphido-bridged cations [M2(CO)8(.mu.-PPh2)]BF4 (M = iron, ruthenium): synthesis, reactivity, and x-ray structure of an isoelectronic and structural analog of Ru2(CO)9

Organometallics, 1990-10, Vol.9 (10), p.2636-2638

1990

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC 1 inhibitors (SHI-1)

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (6), p.1859-1863

2008

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Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXP

Bioorganic & medicinal chemistry letters, 1998-11, Vol.8 (22), p.3137-3142

1998

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Biosynthesis of ML-236C and the hypocholesterolemic agents compactin by Penicillium aurantiogriseum and lovastatin by Aspergillus terreus: determination of the origin of carbon, hydrogen and oxygen atoms by 13C NMR spectrometry and observation of unusual labelling of acetate-derived oxygens by 18O2

Journal of the Chemical Society, Perkin Transactions 1, 1996 (19), p.2357

1996

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Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (16), p.2413-2418

1999

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ChemInform Abstract: A Divergent Approach to the Synthesis of 3-Substituted-2-pyrazolines: Suzuki Cross-Coupling of 3-Sulfonyloxy-2-pyrazolines

ChemInform, 2010-01, Vol.41 (2), p.no-no

2010

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Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)

A Divergent Approach to the Synthesis of 3-Substituted-2-pyrazolines: Suzuki Cross-Coupling of 3-Sulfonyloxy-2-pyrazolines

Histone Deacetylase Inhibitors

A New Strategy for the Synthesis of Benzylic Sulfonamides: Palladium-Catalyzed Arylation and Sulfonamide Metathesis

Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor

Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue

Aminosuberoyl hydroxamic acids (ASHAs): A potent new class of HDAC inhibitors

Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor

Benzo[b]thiophene-based histone deacetylase inhibitors

Design of novel histone deacetylase inhibitors

Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)

Revision of the biosynthetic origin of oxygens in mevinolin (lovastatin), a hypocholesterolemic drug from Aspergillus terreus MF 4845

Putative Diels−Alder-Catalyzed Cyclization during the Biosynthesis of Lovastatin

Yeast Geranylgeranyltransferase Type-II: Steady State Kinetic Studies of the Recombinant Enzyme

Suppression of racemization in the carbonylation of amino acid-derived aryl triflates

Garden music

Novel phosphido-bridged cations [M2(CO)8(.mu.-PPh2)]BF4 (M = iron, ruthenium): synthesis, reactivity, and x-ray structure of an isoelectronic and structural analog of Ru2(CO)9

Phenylglycine and phenylalanine derivatives as potent and selective HDAC 1 inhibitors (SHI-1)

Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXP

Biosynthesis of ML-236C and the hypocholesterolemic agents compactin by Penicillium aurantiogriseum and lovastatin by Aspergillus terreus: determination of the origin of carbon, hydrogen and oxygen atoms by 13C NMR spectrometry and observation of unusual labelling of acetate-derived oxygens by 18O2

Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays

ChemInform Abstract: A Divergent Approach to the Synthesis of 3-Substituted-2-pyrazolines: Suzuki Cross-Coupling of 3-Sulfonyloxy-2-pyrazolines

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