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The tension mounts: stress fibers as force-generating mechanotransducers

The Journal of cell biology, 2013-01, Vol.200 (1), p.9-19

2013

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Endothelial signaling in paracellular and transcellular leukocyte transmigration

Frontiers in bioscience, 2009-01, Vol.14 (7), p.2522-2545

Wittchen, Erika S

2009

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Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif

PloS one, 2009-11, Vol.4 (11), p.e8045-e8045

2009

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Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol

Circulation research, 2019-01, Vol.124 (1), p.38-51

2019

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A Rnd3/p190RhoGAP pathway regulates RhoA activity in idiopathic pulmonary fibrosis fibroblasts

Molecular biology of the cell, 2018-09, Vol.29 (18), p.2165-2175

2018

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Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions

Arteriosclerosis, thrombosis, and vascular biology, 2018-10, Vol.38 (10), p.2410-2422

2018

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The role of endothelial MERTK during the inflammatory response in lungs

PloS one, 2019-12, Vol.14 (12), p.e0225051-e0225051

2019

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ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009713-e1009713

2021

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Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo

PloS one, 2013-09, Vol.8 (9), p.e73070-e73070

2013

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Rap1 GTPase Inhibits Leukocyte Transmigration by Promoting Endothelial Barrier Function

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11675-11682

2005

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TNF-α mediates choroidal neovascularization by upregulating VEGF expression in RPE through ROS-dependent β-catenin activation

Molecular vision, 2016-02, Vol.22, p.116-128

2016

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Upregulation of CCR3 by age-related stresses promotes choroidal endothelial cell migration via VEGF-dependent and -independent signaling

Investigative ophthalmology & visual science, 2011-10, Vol.52 (11), p.8271-8277

2011

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Stress Fibers Get a Makeover

Biophysical journal, 2012-11, Vol.103 (10), p.2045-2046

2012

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Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions

Small GTPases, 2011-03, Vol.2 (2), p.65-76

2011

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Rap1 GTPase Inhibits Tumor Necrosis Factor-α–Induced Choroidal Endothelial Migration via NADPH Oxidase– and NF-κB–Dependent Activation of Rac1

The American journal of pathology, 2015-12, Vol.185 (12), p.3316-3325

2015

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Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart

Journal of molecular and cellular cardiology, 2021-01, Vol.150, p.1-11

2021

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Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization

Molecular therapy. Methods & clinical development, 2016, Vol.3 (C), p.16056-16056, Article 16056

2016

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Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor

The Journal of cell biology, 2019-09, Vol.218 (9), p.3153-3160

2019

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Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration

Current opinion in hematology, 2005-01, Vol.12 (1), p.14-21

2005

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The small GTPase Rap1 is a novel regulator of RPE cell barrier function

Investigative ophthalmology & visual science, 2011-09, Vol.52 (10), p.7455-7463

2011

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Regulation of cell adhesion by protein-tyrosine phosphatases: II. Cell-cell adhesion

The Journal of biological chemistry, 2006-06, Vol.281 (24), p.16189-16192

2006

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The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE

Investigative ophthalmology & visual science, 2011-01, Vol.52 (1), p.570-578

2011

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A Phase 1b Trial of Prexasertib in Combination with Standard-of-Care Agents in Advanced or Metastatic Cancer

Targeted oncology, 2021-09, Vol.16 (5), p.569-589

2021

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Activation of Rap1 inhibits NADPH oxidase‐dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization

The FASEB journal, 2014-01, Vol.28 (1), p.265-274

2014

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Exogenous Expression of the Amino-Terminal Half of the Tight Junction Protein ZO-3 Perturbs Junctional Complex Assembly

The Journal of cell biology, 2000-11, Vol.151 (4), p.825-836

2000

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Cell Movement - Physiology
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Endothelial Cells - Metabolism
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Cytoskeleton
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Endothelial Cells - Physiology
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Rac1 Gtp-Binding Protein - Metabolism
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The tension mounts: stress fibers as force-generating mechanotransducers

Endothelial signaling in paracellular and transcellular leukocyte transmigration

Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif

Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol

A Rnd3/p190RhoGAP pathway regulates RhoA activity in idiopathic pulmonary fibrosis fibroblasts

Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions

The role of endothelial MERTK during the inflammatory response in lungs

ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice

Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo

Rap1 GTPase Inhibits Leukocyte Transmigration by Promoting Endothelial Barrier Function

TNF-α mediates choroidal neovascularization by upregulating VEGF expression in RPE through ROS-dependent β-catenin activation

Upregulation of CCR3 by age-related stresses promotes choroidal endothelial cell migration via VEGF-dependent and -independent signaling

Stress Fibers Get a Makeover

Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions

Rap1 GTPase Inhibits Tumor Necrosis Factor-α–Induced Choroidal Endothelial Migration via NADPH Oxidase– and NF-κB–Dependent Activation of Rac1

Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart

Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization

Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor

Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration

The small GTPase Rap1 is a novel regulator of RPE cell barrier function

Regulation of cell adhesion by protein-tyrosine phosphatases: II. Cell-cell adhesion

The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE

A Phase 1b Trial of Prexasertib in Combination with Standard-of-Care Agents in Advanced or Metastatic Cancer

Activation of Rap1 inhibits NADPH oxidase‐dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization

Exogenous Expression of the Amino-Terminal Half of the Tight Junction Protein ZO-3 Perturbs Junctional Complex Assembly

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