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Curcumin, an active constiuent of the ancient medicinal herb Curcuma longa L.: some uses and the establishment and biological basis of medical efficacy

CNS & neurological disorders drug targets, 2013-06, Vol.12 (4), p.487-497

2013

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Synthesis of (−)-11‑O‑Debenzoyltashironin: Neurotrophic Sesquiterpenes Cause Hyperexcitation

Journal of the American Chemical Society, 2017-07, Vol.139 (28), p.9637-9644

2017

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Prediction of human efficacious antidepressant doses using the mouse forced swim test

Pharmacology, biochemistry and behavior, 2017-10, Vol.161, p.22-29

2017

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Rapid-Acting Antidepressants

Current pharmaceutical design, 2018-01, Vol.24 (22), p.2556-2563

2018

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Mood disorders: Regulation by metabotropic glutamate receptors

Biochemical pharmacology, 2008-03, Vol.75 (5), p.997-1006

2008

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(R)-(-)-Ketamine: The Promise of a Novel Treatment for Psychiatric and Neurological Disorders

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6804

2024

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mGlu2/3 receptor antagonism: A mechanism to induce rapid antidepressant effects without ketamine-associated side-effects

Pharmacology, biochemistry and behavior, 2020-03, Vol.190, p.172854, Article 172854

Witkin, Jeffrey M.

2020

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Synthesis and Receptor Binding Studies of α5 GABAAR Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4771

2023

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Evaluation of 5-HT7 receptor antagonism for the treatment of anxiety, depression, and schizophrenia through the use of receptor-deficient mice

Behavioural brain research, 2019-03, Vol.360, p.270-278

2019

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Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice

The Journal of pharmacology and experimental therapeutics, 2006-10, Vol.319 (1), p.254-259

2006

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Potentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement

Neuropsychopharmacology (New York, N.Y.), 2024-01, Vol.49 (1), p.339-340

2024

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The romantic age of pharmacological science

Pharmacology, biochemistry and behavior, 2022-03, Vol.214, p.173354-173354, Article 173354

Witkin, Jeffrey M.

2022

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Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies

Biochemical pharmacology, 2018-09, Vol.155, p.61-70

2018

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Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm

The international journal of neuropsychopharmacology, 2010-10, Vol.13 (9), p.1207-1218

2010

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KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy

Heliyon, 2024-01, Vol.10 (1), p.e23752-e23752, Article e23752

2024

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GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats

Biomolecules (Basel, Switzerland), 2023-01, Vol.13 (2), p.197

2023

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In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

Psychopharmacologia, 2007-07, Vol.193 (1), p.121-136

2007

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Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice

CNS & neurological disorders drug targets, 2017-01, Vol.16 (4), p.492

2017

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ANXIOLYTICS: Origins, drug discovery, and mechanisms

Pharmacology, biochemistry and behavior, 2024-12, Vol.245, p.173858, Article 173858

2024

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Is there a biochemical basis for purinergic P2X3 and P2X4 receptor antagonists to be considered as anti-seizure medications?

Biochemical pharmacology, 2024-04, Vol.222, p.116046, Article 116046

2024

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GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

Pharmacology & therapeutics (Oxford), 2022-06, Vol.234, p.108035-108035, Article 108035

2022

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Clinical investigations of compounds targeting metabotropic glutamate receptors

Pharmacology, biochemistry and behavior, 2022-09, Vol.219, p.173446-173446, Article 173446

2022

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The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions

British journal of pharmacology, 2003-02, Vol.138 (4), p.544-553

2003

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Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611)

CNS & neurological disorders drug targets, 2017-12, Vol.16 (10), p.1099-1110

2017

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Involvement of Striatal and Extrastriatal DARPP-32 in Biochemical and Behavioral Effects of Fluoxetine (Prozac)

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.3182-3187

2002

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Curcumin, an active constiuent of the ancient medicinal herb Curcuma longa L.: some uses and the establishment and biological basis of medical efficacy

Synthesis of (−)-11‑O‑Debenzoyltashironin: Neurotrophic Sesquiterpenes Cause Hyperexcitation

Prediction of human efficacious antidepressant doses using the mouse forced swim test

Rapid-Acting Antidepressants

Mood disorders: Regulation by metabotropic glutamate receptors

(R)-(-)-Ketamine: The Promise of a Novel Treatment for Psychiatric and Neurological Disorders

mGlu2/3 receptor antagonism: A mechanism to induce rapid antidepressant effects without ketamine-associated side-effects

Synthesis and Receptor Binding Studies of α5 GABAAR Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders

Evaluation of 5-HT7 receptor antagonism for the treatment of anxiety, depression, and schizophrenia through the use of receptor-deficient mice

Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice

Potentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement

The romantic age of pharmacological science

Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies

Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm

KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy

GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats

In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice

ANXIOLYTICS: Origins, drug discovery, and mechanisms

Is there a biochemical basis for purinergic P2X3 and P2X4 receptor antagonists to be considered as anti-seizure medications?

GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

Clinical investigations of compounds targeting metabotropic glutamate receptors

The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions

Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611)

Involvement of Striatal and Extrastriatal DARPP-32 in Biochemical and Behavioral Effects of Fluoxetine (Prozac)

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