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Place your BETs: the therapeutic potential of bromodomains

Trends in pharmacological sciences (Regular ed.), 2012-03, Vol.33 (3), p.146-153

2012

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Neuronal control of experimental colitis occurs via sympathetic intestinal innervation

Neurogastroenterology and motility, 2018-03, Vol.30 (3), p.n/a

2018

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Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation

Neurogastroenterology and motility, 2009-01, Vol.21 (1), p.71-77

2009

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Functional and in situ hybridization evidence that preganglionic sympathetic vasoconstrictor neurons express ghrelin receptors

Neuroscience, 2010-03, Vol.166 (2), p.671-679

2010

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FRI0039 An acetyl-histone mimetic blocks inflammatory activation of rheumatoid arthritis fibroblast-like synoviocytes

Annals of the rheumatic diseases, 2013-06, Vol.72 (Suppl 3), p.A381-A381

2013

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5‐hydroxyindalpine, an agonist at the putative 5‐HT1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension‐induced peristalsis in mouse isolated colon

Neurogastroenterology and motility, 2009-07, Vol.21 (7), p.760-e48

2009

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Cyclic Ketone Inhibitors of the Cysteine Protease Cathepsin K

Journal of medicinal chemistry, 2001-03, Vol.44 (5), p.725-736

2001

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Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin

Neuroscience letters, 2006-01, Vol.392 (1), p.79-83

2006

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5-Aryl-pyrazolo[3,4- b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (9), p.1577-1580

2003

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A1.68 An Acetyl-Histone MiMetic blocks inflammatory activation of rheumatoid arthritis fibroblast-like synoviocytes

Annals of the rheumatic diseases, 2014-03, Vol.73 (Suppl 1), p.A29-A30

2014

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CCR2: Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach

Journal of medicinal chemistry, 2003-09, Vol.46 (19), p.4070-4086

2003

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6-Aryl-pyrazolo[3,4- b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3055-3057

2003

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6-Heteroaryl-pyrazolo[3,4- b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3059-3062

2003

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Unsaturated 1,2-amino alcohols and ethers from aziridines and organolithiums

Chemical communications (Cambridge, England), 2004-01 (19), p.2234-2235

2004

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5-Aryl-pyrazolo[3,4- b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (9), p.1581-1584

2003

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Complementary stereoselective conjugate addition reactions on indolo[2,3-a]quinolizine templates

Tetrahedron letters, 2006-03, Vol.47 (12), p.1961-1964

2006

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(1 H-Imidazo[4,5- c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3402-3406

2005

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Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines

Tetrahedron, 2003-12, Vol.59 (49), p.9729-9742

2003

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Organolithium-induced enantioselective alkylative double ring-opening of epoxides: synthesis of enantioenriched unsaturated amino alcohols

Tetrahedron, 2004-04, Vol.60 (16), p.3611-3624

2004

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Enantioselective Alkylative Double Ring Opening of Epoxides: Synthesis of Enantioenriched Unsaturated Diols and Amino Alcohols

Angewandte Chemie International Edition, 2002-11, Vol.41 (22), p.4313-4316

2002

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5‐hydroxyindalpine, an agonist at the putative 5‐HT 1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension‐induced peristalsis in mouse isolated colon

Neurogastroenterology and motility, 2009-07, Vol.21 (7), p.760

2009

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Pyridone derivatives as potent and selective VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2256-2259

2006

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Unsaturated 1,2-Amino Alcohols from Dihydropyrrole Epoxides and Organolithiums

Synlett, 2002-02, Vol.2002 (2), p.310-312

2002

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Conformationally Restricted Indolopiperidine Derivatives as Potent CCR2B Receptor Antagonists

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2177-2180

2001

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Place your BETs: the therapeutic potential of bromodomains

Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762

Neuronal control of experimental colitis occurs via sympathetic intestinal innervation

Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation

Functional and in situ hybridization evidence that preganglionic sympathetic vasoconstrictor neurons express ghrelin receptors

FRI0039 An acetyl-histone mimetic blocks inflammatory activation of rheumatoid arthritis fibroblast-like synoviocytes

5‐hydroxyindalpine, an agonist at the putative 5‐HT1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension‐induced peristalsis in mouse isolated colon

Cyclic Ketone Inhibitors of the Cysteine Protease Cathepsin K

Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin

5-Aryl-pyrazolo[3,4- b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)

A1.68 An Acetyl-Histone MiMetic blocks inflammatory activation of rheumatoid arthritis fibroblast-like synoviocytes

CCR2: Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach

6-Aryl-pyrazolo[3,4- b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)

6-Heteroaryl-pyrazolo[3,4- b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

Unsaturated 1,2-amino alcohols and ethers from aziridines and organolithiums

5-Aryl-pyrazolo[3,4- b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)

Complementary stereoselective conjugate addition reactions on indolo[2,3-a]quinolizine templates

(1 H-Imidazo[4,5- c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors

Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines

Organolithium-induced enantioselective alkylative double ring-opening of epoxides: synthesis of enantioenriched unsaturated amino alcohols

Enantioselective Alkylative Double Ring Opening of Epoxides: Synthesis of Enantioenriched Unsaturated Diols and Amino Alcohols

5‐hydroxyindalpine, an agonist at the putative 5‐HT 1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension‐induced peristalsis in mouse isolated colon

Pyridone derivatives as potent and selective VLA-4 integrin antagonists

Unsaturated 1,2-Amino Alcohols from Dihydropyrrole Epoxides and Organolithiums

Conformationally Restricted Indolopiperidine Derivatives as Potent CCR2B Receptor Antagonists

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