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Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Molecular pharmacology, 2002-05, Vol.61 (5), p.974-981

2002

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Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

Molecular pharmacology, 2002-05, Vol.61 (5), p.964-973

2002

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Ethyl (3S,4aR,6S,8aR)-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester: A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Models of Acute Migraine

Journal of medicinal chemistry, 2002-09, Vol.45 (20), p.4383-4386

2002

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GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: In vitro profile and in vivo analgesic efficacy

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6463-6466

2013

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GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6459-6462

2013

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Molecular Determinants of Tissue Selectivity in Estrogen Receptor Modulators

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (25), p.14105-14110

1997

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Structure−Activity Relationships of Selective Estrogen Receptor Modulators: Modifications to the 2-Arylbenzothiophene Core of Raloxifene

Journal of medicinal chemistry, 1997-01, Vol.40 (2), p.146-167

1997

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Potent benzimidazolone based human β3-adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5691-5694

2006

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Potent benzimidazolone based human beta(3)-adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5691-5694

2006

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Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups

Journal of medicinal chemistry, 1990-01, Vol.33 (1), p.416-429

1990

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Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain

Journal of medicinal chemistry, 2005-06, Vol.48 (13), p.4200-4203

2005

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Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein

Biochemical pharmacology, 1998-09, Vol.56 (6), p.719-727

1998

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Potent benzimidazolone based human beta sub(3)-adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5691-5694

2006

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Potent benzimidazolone based human β 3-adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (21), p.5691-5694

2006

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Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146

Bioorganic & medicinal chemistry letters, 1999-12, Vol.9 (23), p.3381-3386

1999

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Changes in HIV-1 Subtypes B and C Genital Tract RNA in Women and Men After Initiation of Antiretroviral Therapy

Clinical infectious diseases, 2013-07, Vol.57 (2), p.290-297

2013

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Pharmacological characterization of LY335979: A potent cyclopropyldibenzosuberane modulator of P-glycoprotein

Advances in enzyme regulation, 1997, Vol.37, p.335-347

1997

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A structure-function relationship among reserpine and yohimbine analogues in their ability to increase expression of mdr1 and P-glycoprotein in a human colon carcinoma cell line

Molecular pharmacology, 1995-10, Vol.48 (4), p.682-689

1995

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Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice

World journal of gastroenterology : WJG, 2010-02, Vol.16 (6), p.703-712

2010

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Chemdex: quantification and distributions of valence numbers, oxidation numbers, coordination numbers, electron numbers, and covalent bond classes for the elements

Dalton transactions : an international journal of inorganic chemistry, 2024-01, Vol.53 (2), p.493-511

Winter, Mark J

2024

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A global analysis of the impacts of urbanization on bird and plant diversity reveals key anthropogenic drivers

Proceedings of the Royal Society. B, Biological sciences, 2014-04, Vol.281 (1780), p.20133330-20133330

2014

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Strong Converse for the Classical Capacity of Entanglement-Breaking and Hadamard Channels via a Sandwiched Rényi Relative Entropy

Communications in mathematical physics, 2014, Vol.331 (2), p.593-622

2014

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Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

Ethyl (3S,4aR,6S,8aR)-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester: A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Models of Acute Migraine

GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: In vitro profile and in vivo analgesic efficacy

GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models

Molecular Determinants of Tissue Selectivity in Estrogen Receptor Modulators

Structure−Activity Relationships of Selective Estrogen Receptor Modulators: Modifications to the 2-Arylbenzothiophene Core of Raloxifene

Potent benzimidazolone based human β3-adrenergic receptor agonists

Potent benzimidazolone based human beta(3)-adrenergic receptor agonists

Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups

Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain

Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings

Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein

Potent benzimidazolone based human beta sub(3)-adrenergic receptor agonists

Potent benzimidazolone based human β 3-adrenergic receptor agonists

Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146

Changes in HIV-1 Subtypes B and C Genital Tract RNA in Women and Men After Initiation of Antiretroviral Therapy

Pharmacological characterization of LY335979: A potent cyclopropyldibenzosuberane modulator of P-glycoprotein

Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain : 2005 American Chemical Society Award for Computers in Chemical and Pharmaceutical Research

A structure-function relationship among reserpine and yohimbine analogues in their ability to increase expression of mdr1 and P-glycoprotein in a human colon carcinoma cell line

Ethyl (3S, 4aR, 6S, 8aR)-6-(4-ethoxycarbonylimidazol-1-ylmethyl)decahydroisoquinoline-3-c arboxylic ester: A prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine

Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice

Chemdex: quantification and distributions of valence numbers, oxidation numbers, coordination numbers, electron numbers, and covalent bond classes for the elements

A global analysis of the impacts of urbanization on bird and plant diversity reveals key anthropogenic drivers

Strong Converse for the Classical Capacity of Entanglement-Breaking and Hadamard Channels via a Sandwiched Rényi Relative Entropy

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