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Genomics-inspired discovery of natural products

Current opinion in chemical biology, 2011-02, Vol.15 (1), p.22-31

2011

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Exploring the Chemistry and Biology of Vanadium-dependent Haloperoxidases

The Journal of biological chemistry, 2009-07, Vol.284 (28), p.18577-18581

2009

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Synthetic biological approaches to natural product biosynthesis

Current opinion in biotechnology, 2012-10, Vol.23 (5), p.736-743

2012

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Animal biosynthesis of complex polyketides in a photosynthetic partnership

Nature communications, 2020-06, Vol.11 (1), p.2882-2882, Article 2882

2020

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Salinipeptins: Integrated Genomic and Chemical Approaches Reveal Unusual d‑Amino Acid-Containing Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) from a Great Salt Lake Streptomyces sp

ACS chemical biology, 2019-03, Vol.14 (3), p.415-425

2019

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Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases

Journal of the American Chemical Society, 2017-04, Vol.139 (15), p.5317-5320

2017

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Identification and Characterization of the Chaetoviridin and Chaetomugilin Gene Cluster in Chaetomium globosum Reveal Dual Functions of an Iterative Highly-Reducing Polyketide Synthase

Journal of the American Chemical Society, 2012-10, Vol.134 (43), p.17900-17903

2012

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A Community Effort: Combining Functional Amplicon Sequencing and Metagenomics Reveals Potential Biosynthetic Gene Clusters Associated with Protective Phenotypes in Rhizosphere Microbiomes

mSystems, 2021-06, Vol.6 (3), p.e0058721-e0058721

Winter, Jaclyn M

2021

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Expanding the Utility of Bioinformatic Data for the Full Stereostructural Assignments of Marinolides A and B, 24- and 26-Membered Macrolactones Produced by a Chemically Exceptional Marine-Derived Bacterium

Marine drugs, 2023-06, Vol.21 (6), p.367

2023

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Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis

Organic letters, 2016-03, Vol.18 (6), p.1446-1449

2016

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Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis

Journal of the American Chemical Society, 2015-08, Vol.137 (31), p.9885-9893

2015

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Antifungal natural products

Current opinion in biotechnology, 2021-06, Vol.69, p.232-241

2021

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Formation of the Pyridazine Natural Product Azamerone by Biosynthetic Rearrangement of an Aryl Diazoketone

Angewandte Chemie (International ed.), 2009-01, Vol.48 (4), p.767-770

2009

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Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse

Chemical reviews, 2017-04, Vol.117 (8), p.5619-5674

2017

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The Discovery of Acremochlorins O-R from an Acremonium sp. through Integrated Genomic and Molecular Networking

Journal of fungi (Basel), 2024-05, Vol.10 (5), p.365

2024

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Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains

Natural product reports, 2024-07, Vol.41 (7), p.118-125

2024

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Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses

Applied and Environmental Microbiology, 2011-06, Vol.77 (11), p.3617-3625

2011

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Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs

Chembiochem : a European journal of chemical biology, 2015-11, Vol.16 (17), p.2479-2483

2015

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Complementary Genomic, Bioinformatics, and Chemical Approaches Facilitate the Absolute Structure Assignment of Ionostatin, a Linear Polyketide from a Rare Marine-Derived Actinomycete

ACS chemical biology, 2020-09, Vol.15 (9), p.2507-2515

2020

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Discovery and characterization of a cytochalasan biosynthetic cluster from the marine-derived fungus Aspergillus flavipes CNL-338

Journal of antibiotics, 2020-11, Vol.73 (11), p.803-807

2020

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Conformational Control in Diterpene Synthase TlnA: Elucidating the Mechanism of 5–8–6 Skeleton Formation through Ring Expansion

Organic letters, 2024-03, Vol.26 (8), p.1734-1738

2024

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Marinoterpins A–C: Rare Linear Merosesterterpenoids from Marine-Derived Actinomycete Bacteria of the Family Streptomycetaceae

Journal of organic chemistry, 2021-08, Vol.86 (16), p.11140-11148

2021

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Identification and Characterization of a Cryptic Bifunctional Type I Diterpene Synthase Involved in Talaronoid Biosynthesis from a Marine-Derived Fungus

Organic letters, 2022-09, Vol.24 (38), p.7037-7041

2022

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DNA Authentication and Chemical Analysis of Psilocybe Mushrooms Reveal Widespread Misdeterminations in Fungaria and Inconsistencies in Metabolites

Applied and environmental microbiology, 2022-12, Vol.88 (24), p.e0149822-e0149822

2022

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Emerimicins V–X, 15-Residue Peptaibols Discovered from an Acremonium sp. through Integrated Genomic and Chemical Approaches

Journal of natural products (Washington, D.C.), 2021-04, Vol.84 (4), p.1113-1126

2021

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Genomics-inspired discovery of natural products

Exploring the Chemistry and Biology of Vanadium-dependent Haloperoxidases

Synthetic biological approaches to natural product biosynthesis

Animal biosynthesis of complex polyketides in a photosynthetic partnership

Salinipeptins: Integrated Genomic and Chemical Approaches Reveal Unusual d‑Amino Acid-Containing Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) from a Great Salt Lake Streptomyces sp

Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases

Identification and Characterization of the Chaetoviridin and Chaetomugilin Gene Cluster in Chaetomium globosum Reveal Dual Functions of an Iterative Highly-Reducing Polyketide Synthase

A Community Effort: Combining Functional Amplicon Sequencing and Metagenomics Reveals Potential Biosynthetic Gene Clusters Associated with Protective Phenotypes in Rhizosphere Microbiomes

Expanding the Utility of Bioinformatic Data for the Full Stereostructural Assignments of Marinolides A and B, 24- and 26-Membered Macrolactones Produced by a Chemically Exceptional Marine-Derived Bacterium

Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis

Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis

Antifungal natural products

Formation of the Pyridazine Natural Product Azamerone by Biosynthetic Rearrangement of an Aryl Diazoketone

Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse

The Discovery of Acremochlorins O-R from an Acremonium sp. through Integrated Genomic and Molecular Networking

Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains

Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses

Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs

Complementary Genomic, Bioinformatics, and Chemical Approaches Facilitate the Absolute Structure Assignment of Ionostatin, a Linear Polyketide from a Rare Marine-Derived Actinomycete

Discovery and characterization of a cytochalasan biosynthetic cluster from the marine-derived fungus Aspergillus flavipes CNL-338

Conformational Control in Diterpene Synthase TlnA: Elucidating the Mechanism of 5–8–6 Skeleton Formation through Ring Expansion

Marinoterpins A–C: Rare Linear Merosesterterpenoids from Marine-Derived Actinomycete Bacteria of the Family Streptomycetaceae

Identification and Characterization of a Cryptic Bifunctional Type I Diterpene Synthase Involved in Talaronoid Biosynthesis from a Marine-Derived Fungus

DNA Authentication and Chemical Analysis of Psilocybe Mushrooms Reveal Widespread Misdeterminations in Fungaria and Inconsistencies in Metabolites

Emerimicins V–X, 15-Residue Peptaibols Discovered from an Acremonium sp. through Integrated Genomic and Chemical Approaches

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