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Discovery and development of orexin receptor antagonists as therapeutics for insomnia

British journal of pharmacology, 2014-01, Vol.171 (2), p.283-293

2014

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0018 DATA MINING OF MULTIPLE GENOMICS DATASETS UNCOVERS CONVERGENT GENE NETWORKS INTEGRATING CIRCADIAN TIMING AND HOMEOSTATIC DRIVE FOR SLEEP REGULATION

Sleep (New York, N.Y.), 2017-04, Vol.40 (suppl_1), p.A7-A7

2017

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Evidence That Mouse Brain Neuropathy Target Esterase Is a Lysophospholipase

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7983-7987

2003

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Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity

Nature genetics, 2003-04, Vol.33 (4), p.477-485

2003

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0103 REM SLEEP IS INDUCED BY DUAL AND OREXIN 2 RECEPTOR ANTAGONISTS VIA MECHANISMS BEYOND ALPHA1-NORADRENERGIC SIGNALING

Sleep (New York, N.Y.), 2017-04, Vol.40 (suppl_1), p.A39-A39

2017

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0018 DATA MINING OF MULTIPLE GENOMICS DATASETS UNCOVERS CONVERGENT GENE NETWORKS INTEGRATING CIRCADIAN TIMING AND HOMEOSTATIC DRIVE FOR SLEEP REGULATION

Sleep (New York, N.Y.), 2017-04, Vol.40 (suppl_1), p.A7-A7

2017

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0280 A RECIPROCAL RELATIONSHIP BETWEEN SLEEP AND ALZHEIMER’S DISEASE?

Sleep (New York, N.Y.), 2017-04, Vol.40 (suppl_1), p.A103-A103

2017

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Ataxia telangiectasia mutated is essential during adult neurogenesis

Genes & development, 2001-03, Vol.15 (5), p.554-566

2001

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The Peroxisome Proliferator Response Element of the Gene Encoding the Peroxisomal β-Oxidation Enzyme Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydrogenase Is a Target for Constitutive Androstane Receptor β/9-cis-Retinoic Acid Receptor-mediated Transactivation

The Journal of biological chemistry, 2000-02, Vol.275 (6), p.4345-4350

2000

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Aberrant recombination involving the granzyme locus occurs in Atm−/− T-cell lymphomas

Human molecular genetics, 2005-09, Vol.14 (18), p.2671-2684

2005

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Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes

Molecular and cellular endocrinology, 1996-02, Vol.116 (2), p.213-221

1996

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Cross-talk between Orphan Nuclear Hormone Receptor RZRα and Peroxisome Proliferator-activated Receptor α in Regulation of the Peroxisomal Hydratase-Dehydrogenase Gene

The Journal of biological chemistry, 1998-11, Vol.273 (47), p.31442-31448

1998

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A p56(lck) ligand serves as a coactivator of an orphan nuclear hormone receptor

The Journal of biological chemistry, 1996-11, Vol.271 (44), p.27197-27200

1996

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Interplay of the Peroxisome Proliferator-activated Receptor and the Thyroid Hormone Receptor-signaling Pathways in Regulating Peroxisome Proliferator-responsive Genes

Annals of the New York Academy of Sciences, 1996-12, Vol.804 (1), p.214-230

1996

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Calreticulin modulates the in vitro DNA binding but not the in vivo transcriptional activation by peroxisome proliferator-activated receptor/retinoid X receptor heterodimers

Molecular and cellular endocrinology, 1995-06, Vol.111 (2), p.175-179

1995

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Free radicals in inflammation: second messengers and mediators of tissue destruction

British medical bulletin, 1993, Vol.49 (3), p.506-522

1993

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A synthetic 10‐kD heat shock protein (hsp10) from Mycobacterium tuberculosis modulates adjuvant arthritis

Clinical and experimental immunology, 1996-03, Vol.103 (3), p.384-390

1996

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The heat shock protein response and its role in inflammatory disease

Annals of the rheumatic diseases, 1990-02, Vol.49 (2), p.128-132

1990

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PPD and hsp65 induced monoarthritis initiates spontaneous recurrent flares in Lewis rats

Annals of the rheumatic diseases, 1995-01, Vol.54 (1), p.59-65

1995

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Arthritogenic potential of the 65 kDa stress protein--an experimental model

Annals of the rheumatic diseases, 1994-03, Vol.53 (3), p.197-201

1994

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The transcription factors hypoxia‐inducible factor 1α and Ets‐1 colocalize in the hypoxic synovium of inflamed joints in adjuvant‐induced arthritis

Arthritis and rheumatism, 2004-01, Vol.50 (1), p.291-296

2004

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Discovery and development of orexin receptor antagonists as therapeutics for insomnia

0018 DATA MINING OF MULTIPLE GENOMICS DATASETS UNCOVERS CONVERGENT GENE NETWORKS INTEGRATING CIRCADIAN TIMING AND HOMEOSTATIC DRIVE FOR SLEEP REGULATION

Evidence That Mouse Brain Neuropathy Target Esterase Is a Lysophospholipase

Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity

0103 REM SLEEP IS INDUCED BY DUAL AND OREXIN 2 RECEPTOR ANTAGONISTS VIA MECHANISMS BEYOND ALPHA1-NORADRENERGIC SIGNALING

0018 DATA MINING OF MULTIPLE GENOMICS DATASETS UNCOVERS CONVERGENT GENE NETWORKS INTEGRATING CIRCADIAN TIMING AND HOMEOSTATIC DRIVE FOR SLEEP REGULATION

0280 A RECIPROCAL RELATIONSHIP BETWEEN SLEEP AND ALZHEIMER’S DISEASE?

Ataxia telangiectasia mutated is essential during adult neurogenesis

The Peroxisome Proliferator Response Element of the Gene Encoding the Peroxisomal β-Oxidation Enzyme Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydrogenase Is a Target for Constitutive Androstane Receptor β/9-cis-Retinoic Acid Receptor-mediated Transactivation

Aberrant recombination involving the granzyme locus occurs in Atm−/− T-cell lymphomas

Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes

Cross-talk between Orphan Nuclear Hormone Receptor RZRα and Peroxisome Proliferator-activated Receptor α in Regulation of the Peroxisomal Hydratase-Dehydrogenase Gene

A p56(lck) ligand serves as a coactivator of an orphan nuclear hormone receptor

Interplay of the Peroxisome Proliferator-activated Receptor and the Thyroid Hormone Receptor-signaling Pathways in Regulating Peroxisome Proliferator-responsive Genes

Calreticulin modulates the in vitro DNA binding but not the in vivo transcriptional activation by peroxisome proliferator-activated receptor/retinoid X receptor heterodimers

Free radicals in inflammation: second messengers and mediators of tissue destruction

A synthetic 10‐kD heat shock protein (hsp10) from Mycobacterium tuberculosis modulates adjuvant arthritis

The heat shock protein response and its role in inflammatory disease

PPD and hsp65 induced monoarthritis initiates spontaneous recurrent flares in Lewis rats

Arthritogenic potential of the 65 kDa stress protein--an experimental model

The transcription factors hypoxia‐inducible factor 1α and Ets‐1 colocalize in the hypoxic synovium of inflamed joints in adjuvant‐induced arthritis

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