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Targeted protein degradation by PROTACs

Pharmacology & therapeutics (Oxford), 2017-06, Vol.174, p.138-144

2017

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PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (26), p.7124-7129

2016

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Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.583-598

2018

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Recent advances in the evolutionary engineering of industrial biocatalysts

Genomics (San Diego, Calif.), 2014-12, Vol.104 (6), p.406-411

2014

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Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor

Clinical cancer research, 2007-03, Vol.13 (5), p.1576-1583

2007

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Evolved osmotolerant Escherichia coli mutants frequently exhibit defective N-acetylglucosamine catabolism and point mutations in cell shape-regulating protein MreB

Applied and Environmental Microbiology, 2014-06, Vol.80 (12), p.3729-3740

2014

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Bacterial Recombineering: Genome Engineering via Phage-Based Homologous Recombination

ACS synthetic biology, 2015-11, Vol.4 (11), p.1176-1185

2015

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Prenatal exposure to environmental toxins and comprehensive dental findings in a population cohort of children

BMC oral health, 2024-03, Vol.24 (1), p.326-326, Article 326

2024

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Clinical experience of MEK inhibitors in cancer therapy

Biochimica et biophysica acta, 2007-08, Vol.1773 (8), p.1248-1255

2007

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Transcriptional analysis of Lactobacillus brevis to N-butanol and ferulic acid stress responses

PloS one, 2011-08, Vol.6 (8), p.e21438

2011

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A Randomized Double-Blind, Placebo-Controlled Multicenter Study to Evaluate the Efficacy and Safety of Two Doses of the Tramadol Orally Disintegrating Tablet for the Treatment of Premature Ejaculation Within Less Than 2 Minutes

European urology, 2012-04, Vol.61 (4), p.736-743

2012

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Visualizing evolution in real time to determine the molecular mechanisms of n-butanol tolerance in Escherichia coli

Metabolic engineering, 2012-09, Vol.14 (5), p.579-590

2012

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Refactoring the Genetic Code for Increased Evolvability

mBio, 2017-11, Vol.8 (6)

2017

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Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Chemistry & biology, 2015-06, Vol.22 (6), p.755-763

2015

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Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors

Molecular cancer therapeutics, 2022-03, Vol.21 (3), p.397-406

2022

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Cross-cultural adaptation of a Spanish version of a previously validated HPV survey that evaluates dental students' knowledge, perception and clinical practices in Latin America

BMC oral health, 2022-03, Vol.22 (1), p.72-8, Article 72

2022

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A Multi-state Evaluation of Oral Health Students’ Knowledge of Human Papillomavirus-Related Oropharyngeal Cancer and HPV Vaccination

Journal of cancer education, 2020-10, Vol.35 (5), p.1017-1025

2020

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A novel assay for cobalt-albumin binding and its potential as a marker for myocardial ischemia—a preliminary report

The Journal of emergency medicine, 2000-11, Vol.19 (4), p.311-315

2000

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US oral health students' willingness to train and administer the HPV vaccine in dental practices

Preventive medicine reports, 2019-09, Vol.15, p.100957-100957, Article 100957

2019

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Complex systems in metabolic engineering

Current opinion in biotechnology, 2015-12, Vol.36 (C), p.107-114

2015

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The LASER database: Formalizing design rules for metabolic engineering

Metabolic engineering communications, 2015-12, Vol.2 (C), p.30-38

2015

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The Tolerome: A Database of Transcriptome-Level Contributions to Diverse Escherichia coli Resistance and Tolerance Phenotypes

ACS synthetic biology, 2017-12, Vol.6 (12), p.2302-2315

2017

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Immediate Dental Implant Placement in HIV‐Positive Patients Receiving Highly Active Antiretroviral Therapy: A Report of Two Cases and a Review of the Literature of Implants Placed in HIV‐Positive Individuals

Journal of periodontology (1970), 2011-03, Vol.82 (3), p.505-511

2011

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Progress towards therapeutic small molecule MEK inhibitors for use in cancer therapy

Current topics in medicinal chemistry, 2005-01, Vol.5 (2), p.215-229

2005

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Identification of novel isoform-selective inhibitors within class I histone deacetylases

The Journal of pharmacology and experimental therapeutics, 2003-11, Vol.307 (2), p.720-728

2003

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Targeted protein degradation by PROTACs

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1

Recent advances in the evolutionary engineering of industrial biocatalysts

Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor

Evolved osmotolerant Escherichia coli mutants frequently exhibit defective N-acetylglucosamine catabolism and point mutations in cell shape-regulating protein MreB

Bacterial Recombineering: Genome Engineering via Phage-Based Homologous Recombination

Prenatal exposure to environmental toxins and comprehensive dental findings in a population cohort of children

Clinical experience of MEK inhibitors in cancer therapy

Transcriptional analysis of Lactobacillus brevis to N-butanol and ferulic acid stress responses

A Randomized Double-Blind, Placebo-Controlled Multicenter Study to Evaluate the Efficacy and Safety of Two Doses of the Tramadol Orally Disintegrating Tablet for the Treatment of Premature Ejaculation Within Less Than 2 Minutes

Visualizing evolution in real time to determine the molecular mechanisms of n-butanol tolerance in Escherichia coli

Refactoring the Genetic Code for Increased Evolvability

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors

Cross-cultural adaptation of a Spanish version of a previously validated HPV survey that evaluates dental students' knowledge, perception and clinical practices in Latin America

A Multi-state Evaluation of Oral Health Students’ Knowledge of Human Papillomavirus-Related Oropharyngeal Cancer and HPV Vaccination

A novel assay for cobalt-albumin binding and its potential as a marker for myocardial ischemia—a preliminary report

US oral health students' willingness to train and administer the HPV vaccine in dental practices

Complex systems in metabolic engineering

The LASER database: Formalizing design rules for metabolic engineering

The Tolerome: A Database of Transcriptome-Level Contributions to Diverse Escherichia coli Resistance and Tolerance Phenotypes

Immediate Dental Implant Placement in HIV‐Positive Patients Receiving Highly Active Antiretroviral Therapy: A Report of Two Cases and a Review of the Literature of Implants Placed in HIV‐Positive Individuals

Progress towards therapeutic small molecule MEK inhibitors for use in cancer therapy

Identification of novel isoform-selective inhibitors within class I histone deacetylases

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