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Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.2015-2026

2001

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Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance

Oncogene, 2017-08, Vol.36 (34), p.4843-4858

2017

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An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage

Cancer research (Chicago, Ill.), 2000-02, Vol.60 (3), p.566-572

2000

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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Oncogene, 1999-07, Vol.18 (28), p.4047-4054

1999

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Synthesis of 6-Aza-bicyclo[3,2,1]octan-3-ones via Vinylogous Imide Photochemistry: An Approach to the Synthesis of the Hetisine Alkaloids

Journal of the American Chemical Society, 2001-08, Vol.123 (30), p.7429-7430

2001

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TNF-α modulates angiopoietin-1 expression in rheumatoid synovial fibroblasts via the NF-κB signalling pathway

Biochemical and biophysical research communications, 2005-03, Vol.328 (2), p.409-414

2005

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Selective Metals Determination with a Photoreversible Spirobenzopyran

Analytical chemistry (Washington), 1999-12, Vol.71 (23), p.5322-5327

1999

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The codependence of angiogenesis and chronic inflammation

The FASEB journal, 1997-05, Vol.11 (6), p.457-465

1997

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Fatty acid and phospholipid selectivity of different phospholipase A2 enzymes studied by using a mammalian membrane as substrate

Biochemical journal, 1994-08, Vol.301 ( Pt 3) (3), p.721-726

1994

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Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension

Critical care medicine, 2001-05, Vol.29 (5), p.1000-1005

2001

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Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality

The Journal of biological chemistry, 2000-05, Vol.275 (21), p.16007-16014

2000

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Progress towards therapeutic small molecule MEK inhibitors for use in cancer therapy

Current topics in medicinal chemistry, 2005-01, Vol.5 (2), p.215

2005

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Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

The Journal of biological chemistry, 2000-04, Vol.275 (14), p.10342

2000

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The First Total Syntheses of Ircinol A, Ircinal A, and Manzamines A and D

Journal of the American Chemical Society, 1998-07, Vol.120 (25), p.6425-6426

1998

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Targeted protein degradation by PROTACs

Pharmacology & therapeutics (Oxford), 2017-06, Vol.174, p.138-144

2017

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Control of arachidonate levels within inflammatory cells

Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, 1996, Vol.1299 (1), p.1-15

1996

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Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models

The Journal of pharmacology and experimental therapeutics, 1998-02, Vol.284 (2), p.687

1998

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Effects of CoA-independent transacylase inhibitors on the production of lipid inflammatory mediators

The Journal of pharmacology and experimental therapeutics, 1995-09, Vol.274 (3), p.1338

1995

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SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock

The Journal of pharmacology and experimental therapeutics, 1995-09, Vol.274 (3), p.1254

1995

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Effects of scalaradial, a type II phospholipase A2 inhibitor, on human neutrophil arachidonic acid mobilization and lipid mediator formation

The Journal of pharmacology and experimental therapeutics, 1994-02, Vol.268 (2), p.709

1994

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Endogenous retinoid X receptors can function as hormone receptors in pituitary cells

Molecular and Cellular Biology, 1994-11, Vol.14 (11), p.7105-7110

1994

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Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells

The Journal of pharmacology and experimental therapeutics, 1996-11, Vol.279 (2), p.956

1996

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Effect of continuous exposure to selective D1 and D2 dopaminergic agonists on rotational behavior in supersensitive mice

The Journal of pharmacology and experimental therapeutics, 1989-05, Vol.249 (2), p.507

1989

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Pharmacological characterization of SB 202235, a potent and selective 5-lipoxygenase inhibitor: effects in models of allergic asthma

The Journal of pharmacology and experimental therapeutics, 1995-06, Vol.273 (3), p.1147

1995

Volltextzugriff (PDF)

Estimate of global methane emissions from coal mines

Chemosphere (Oxford), 1993, Vol.26 (1), p.453-472

1993

Volltextzugriff (PDF)

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Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7

Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance

An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Synthesis of 6-Aza-bicyclo[3,2,1]octan-3-ones via Vinylogous Imide Photochemistry: An Approach to the Synthesis of the Hetisine Alkaloids

TNF-α modulates angiopoietin-1 expression in rheumatoid synovial fibroblasts via the NF-κB signalling pathway

Selective Metals Determination with a Photoreversible Spirobenzopyran

The codependence of angiogenesis and chronic inflammation

Fatty acid and phospholipid selectivity of different phospholipase A2 enzymes studied by using a mammalian membrane as substrate

Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension

Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality

Progress towards therapeutic small molecule MEK inhibitors for use in cancer therapy

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

The First Total Syntheses of Ircinol A, Ircinal A, and Manzamines A and D

Targeted protein degradation by PROTACs

Control of arachidonate levels within inflammatory cells

Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models

Effects of CoA-independent transacylase inhibitors on the production of lipid inflammatory mediators

SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock

Effects of scalaradial, a type II phospholipase A2 inhibitor, on human neutrophil arachidonic acid mobilization and lipid mediator formation

Endogenous retinoid X receptors can function as hormone receptors in pituitary cells

Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells

Effect of continuous exposure to selective D1 and D2 dopaminergic agonists on rotational behavior in supersensitive mice

Pharmacological characterization of SB 202235, a potent and selective 5-lipoxygenase inhibitor: effects in models of allergic asthma

Estimate of global methane emissions from coal mines

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