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Mining a human transcriptome database for chemical modulators of NRF2

PloS one, 2020-09, Vol.15 (9), p.e0239367

2020

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High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability

Archives of toxicology, 2019-10, Vol.93 (10), p.2895-2911

2019

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Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

Nature communications, 2019-07, Vol.10 (1), p.2983-16, Article 2983

2019

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Quantitative High Content Imaging of Cellular Adaptive Stress Response Pathways in Toxicity for Chemical Safety Assessment

Chemical research in toxicology, 2014-03, Vol.27 (3), p.338-355

2014

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FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells

Biochemical pharmacology, 2019-11, Vol.169, p.113640-113640, Article 113640

2019

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Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

Frontiers in genetics, 2018-10, Vol.9, p.429-429

2018

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Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

Frontiers in genetics, 2019-06, Vol.10, p.517-517

2019

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High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities

Archives of toxicology, 2017-03, Vol.91 (3), p.1367-1383

2017

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Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury

Archives of toxicology, 2018-05, Vol.92 (5), p.1797-1814

2018

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Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses

Toxicology in vitro, 2022-10, Vol.84, p.105419-105419, Article 105419

2022

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Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity

Archives of toxicology, 2016-05, Vol.90 (5), p.1163-1179

2016

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Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes

Toxicology in vitro, 2021-06, Vol.73, p.105107, Article 105107

2021

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Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury

Biochemical pharmacology, 2021-08, Vol.190, p.114591, Article 114591

2021

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Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity

Toxicological sciences, 2014-07, Vol.140 (1), p.144-159

2014

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Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage

Chemical research in toxicology, 2017-04, Vol.30 (4), p.923-933

2017

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Collaborative SAR Modeling and Prospective In Vitro Validation of Oxidative Stress Activation in Human HepG2 Cells

Journal of chemical information and modeling, 2023-09, Vol.63 (17), p.5433-5445

2023

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System Microscopy of Stress Response Pathways in Cholestasis Research

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.187

2019

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The integrated stress response‐related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability

Liver international, 2024-03, Vol.44 (3), p.760-775

2024

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Functional analysis of high-content high-throughput imaging data

Journal of applied statistics, 2017-08, Vol.44 (11), p.1903-1919

2017

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Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells

Breast cancer research : BCR, 2015-07, Vol.17 (1), p.97, Article 97

2015

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Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-[kappa]B activation and sensitizes toward TNF[alpha]-induced cytotoxicity

Archives of toxicology, 2016-05, Vol.90 (5), p.1163

2016

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Developmental milestones and daily living skills in individuals with Angelman syndrome

Journal of neurodevelopmental disorders, 2024-06, Vol.16 (1), p.32-15

2024

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Mobilising Q methodology within a realist evaluation: Lessons from an empirical study

Evaluation (London, England. 1995), 2019-10, Vol.25 (4), p.430-448

2019

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Mining a human transcriptome database for chemical modulators of NRF2

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability

Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

Quantitative High Content Imaging of Cellular Adaptive Stress Response Pathways in Toxicity for Chemical Safety Assessment

FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities

Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury

Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity

Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes

Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage

Collaborative SAR Modeling and Prospective In Vitro Validation of Oxidative Stress Activation in Human HepG2 Cells

System Microscopy of Stress Response Pathways in Cholestasis Research

The integrated stress response‐related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability

Toxicogenomics directory of chemically exposed human hepatocytes

Functional analysis of high-content high-throughput imaging data

Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells

Correction to: Toxicogenomics directory of chemically exposed human hepatocytes

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-[kappa]B activation and sensitizes toward TNF[alpha]-induced cytotoxicity

Developmental milestones and daily living skills in individuals with Angelman syndrome

Mobilising Q methodology within a realist evaluation: Lessons from an empirical study

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