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NOS2 as an Emergent Player in Progression of Cancer

Antioxidants & redox signaling, 2017-06, Vol.26 (17), p.963

2017

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Nitric oxide and redox mechanisms in the immune response

Journal of leukocyte biology, 2011-06, Vol.89 (6), p.873-891

2011

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Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

Nature communications, 2020-02, Vol.11 (1), p.698-17, Article 698

2020

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Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

Journal of the American College of Cardiology, 2010-12, Vol.56 (25), p.2115-2125

2010

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Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness

BMC cancer, 2020-09, Vol.20 (1), p.929-13, Article 929

2020

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Nitric Oxide in Macrophage Immunometabolism: Hiding in Plain Sight

Metabolites, 2020-10, Vol.10 (11), p.429

2020

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Biological signaling by small inorganic molecules

Coordination chemistry reviews, 2016-01, Vol.306 (Pt 2), p.708-723

2016

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The chemical biology of nitric oxide: Implications in cellular signaling

Free radical biology & medicine, 2008-07, Vol.45 (1), p.18-31

2008

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Signaling and stress: The redox landscape in NOS2 biology

Free radical biology & medicine, 2015-10, Vol.87, p.204-225

2015

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Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.6323-6328

2014

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Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (49), p.13030-13035

2017

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Nitric Oxide Synthase-2-Derived Nitric Oxide Drives Multiple Pathways of Breast Cancer Progression

Antioxidants & redox signaling, 2017-06, Vol.26 (18), p.1044

2017

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Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations

American journal of physiology. Regulatory, integrative and comparative physiology, 2004-03, Vol.286 (3), p.431-R444

2004

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Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity

Clinical cancer research, 2013-03, Vol.19 (6), p.1340-1346

2013

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Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming

Nature communications, 2023-08, Vol.14 (1), p.5114-5114, Article 5114

2023

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Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

Free radical biology & medicine, 2011-05, Vol.50 (10), p.1368-1381

2011

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Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3843-3854

2010

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Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production

Redox biology, 2016-12, Vol.10 (C), p.12-23

2016

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Persulfides and the cellular thiol landscape

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.7505-7506

2014

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Understanding the tumour micro‐environment communication network from an NOS2/COX2 perspective

British journal of pharmacology, 2019-01, Vol.176 (2), p.155-176

2019

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Role of nitric oxide in pancreatic cancer cells exhibiting the invasive phenotype

Redox biology, 2019-04, Vol.22, p.101158-101158, Article 101158

2019

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Nitroxyl-Mediated Disulfide Bond Formation Between Cardiac Myofilament Cysteines Enhances Contractile Function

Circulation research, 2012-09, Vol.111 (8), p.1002-1011

2012

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NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer

International journal of molecular sciences, 2024-06, Vol.25 (11), p.6103

2024

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Nitric Oxide Donor DETA/NO Inhibits the Growth of Endometrial Cancer Cells by Upregulating the Expression of RASSF1 and CDKN1A

Molecules (Basel, Switzerland), 2019-10, Vol.24 (20), p.3722

2019

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CD47 Is Necessary for Inhibition of Nitric Oxide-stimulated Vascular Cell Responses by Thrombospondin-1

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26069-26080

2006

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NOS2 as an Emergent Player in Progression of Cancer

Nitric oxide and redox mechanisms in the immune response

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness

Nitric Oxide in Macrophage Immunometabolism: Hiding in Plain Sight

Biological signaling by small inorganic molecules

The chemical biology of nitric oxide: Implications in cellular signaling

Signaling and stress: The redox landscape in NOS2 biology

Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

Nitric Oxide Synthase-2-Derived Nitric Oxide Drives Multiple Pathways of Breast Cancer Progression

Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations

Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity

Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients

Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production

Persulfides and the cellular thiol landscape

Understanding the tumour micro‐environment communication network from an NOS2/COX2 perspective

Role of nitric oxide in pancreatic cancer cells exhibiting the invasive phenotype

Nitroxyl-Mediated Disulfide Bond Formation Between Cardiac Myofilament Cysteines Enhances Contractile Function

NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer

Nitric Oxide Donor DETA/NO Inhibits the Growth of Endometrial Cancer Cells by Upregulating the Expression of RASSF1 and CDKN1A

CD47 Is Necessary for Inhibition of Nitric Oxide-stimulated Vascular Cell Responses by Thrombospondin-1

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