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AHR in the intestinal microenvironment: safeguarding barrier function

Nature reviews. Gastroenterology & hepatology, 2021-08, Vol.18 (8), p.559-570

2021

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Evidence for New Light-Independent Pathways for Generation of the Endogenous Aryl Hydrocarbon Receptor Agonist FICZ

Chemical research in toxicology, 2016-01, Vol.29 (1), p.75-86

2016

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Quercetin, Resveratrol, and Curcumin Are Indirect Activators of the Aryl Hydrocarbon Receptor (AHR)

Chemical research in toxicology, 2012-09, Vol.25 (9), p.1878-1884

2012

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Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4479-4484

2012

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Aryl Hydrocarbon Receptor Activation and Developmental Toxicity in Zebrafish in Response to Soil Extracts Containing Unsubstituted and Oxygenated PAHs

Environmental science & technology, 2015-03, Vol.49 (6), p.3869-3877

2015

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The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b]carbazole Is Present in Humans

The Journal of biological chemistry, 2009-01, Vol.284 (5), p.2690-2696

2009

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Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation

Pharmacological research, 2023-08, Vol.194, p.106848-106848, Article 106848

2023

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Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner

Biochemical pharmacology, 2016-06, Vol.110-111, p.117-129

2016

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Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation

Disease models & mechanisms, 2021-12, Vol.14 (12), p.1

2021

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TnP and AHR-CYP1A1 Signaling Crosstalk in an Injury-Induced Zebrafish Inflammation Model

Pharmaceuticals (Basel, Switzerland), 2024-08, Vol.17 (9), p.1155

2024

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Kinetics and toxicity of an environmentally relevant mixture of halogenated organic compounds in zebrafish embryo

Aquatic toxicology, 2022-11, Vol.252, p.106311-106311, Article 106311

2022

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Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2- b]carbazole

Chemico-biological interactions, 2004-10, Vol.149 (2), p.151-164

2004

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Feedback control of AHR signalling regulates intestinal immunity

Nature (London), 2017-02, Vol.542 (7640), p.242-245

2017

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Toxicokinetics of Perfluorinated Alkyl Acids Influences Their Toxic Potency in the Zebrafish Embryo (Danio rerio)

Environmental science & technology, 2019-04, Vol.53 (7), p.3898-3907

2019

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Non-additive mixture effects of benzo[a]pyrene and pesticides in vitro and in vivo: Role of AhR signaling

Environmental pollution (1987), 2023-01, Vol.316 (Pt 1), p.120510, Article 120510

2023

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Transcriptomic and functional effects from a chemical mixture based on the exposure profile in Baltic Sea salmon, on metabolic and immune functions in zebrafish embryo

Environment international, 2024-10, Vol.192, p.109018, Article 109018

2024

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Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells

Biochemical pharmacology, 2018-05, Vol.151, p.47-58

2018

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The influence of AHR on immune and tissue biology

EMBO molecular medicine, 2024-09

2024

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Retene, pyrene and phenanthrene cause distinct molecular-level changes in the cardiac tissue of rainbow trout (Oncorhynchus mykiss) larvae, part 1 – Transcriptomics

The Science of the total environment, 2020-11, Vol.745, p.141031-141031, Article 141031

2020

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Exposure to retene, fluoranthene, and their binary mixture causes distinct transcriptomic and apical outcomes in rainbow trout (Oncorhynchus mykiss) yolk sac alevins

Aquatic toxicology, 2022-03, Vol.244, p.106083-106083, Article 106083

2022

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P29 Manuka honey downregulates IL-4-induced CCL26 via activation of the aryl hydrocarbon receptor

BRITISH JOURNAL OF DERMATOLOGY, 2023, Vol.189 (1), p.e25-e26

2023

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Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) – A comparison with lysosomotropic drugs

Chemico-biological interactions, 2018-02, Vol.281, p.1-10

2018

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Tn P and AHR-CYP1A1 Signaling Crosstalk in an Injury-Induced Zebrafish Inflammation Model

Pharmaceuticals (Basel, Switzerland), 2024-08, Vol.17 (9)

2024

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PBTK modeled perfluoroalkyl acid kinetics in zebrafish eleutheroembryos suggests impacts on bioconcentrations by chorion porosity dynamics

Toxicology in vitro, 2023-06, Vol.89, p.105588-105588, Article 105588

2023

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Endogenous AhR agonist FICZ accumulates in rainbow trout (Oncorhynchus mykiss) alevins exposed to a mixture of two PAHs, retene and fluoranthene

Ecotoxicology (London), 2022-11, Vol.31 (9), p.1382-1389

2022

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AHR in the intestinal microenvironment: safeguarding barrier function

Evidence for New Light-Independent Pathways for Generation of the Endogenous Aryl Hydrocarbon Receptor Agonist FICZ

Quercetin, Resveratrol, and Curcumin Are Indirect Activators of the Aryl Hydrocarbon Receptor (AHR)

Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor

Aryl Hydrocarbon Receptor Activation and Developmental Toxicity in Zebrafish in Response to Soil Extracts Containing Unsubstituted and Oxygenated PAHs

The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b]carbazole Is Present in Humans

Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation

Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner

Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation

TnP and AHR-CYP1A1 Signaling Crosstalk in an Injury-Induced Zebrafish Inflammation Model

Kinetics and toxicity of an environmentally relevant mixture of halogenated organic compounds in zebrafish embryo

Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2- b]carbazole

Feedback control of AHR signalling regulates intestinal immunity

Toxicokinetics of Perfluorinated Alkyl Acids Influences Their Toxic Potency in the Zebrafish Embryo (Danio rerio)

Non-additive mixture effects of benzo[a]pyrene and pesticides in vitro and in vivo: Role of AhR signaling

Transcriptomic and functional effects from a chemical mixture based on the exposure profile in Baltic Sea salmon, on metabolic and immune functions in zebrafish embryo

Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells

The influence of AHR on immune and tissue biology

Retene, pyrene and phenanthrene cause distinct molecular-level changes in the cardiac tissue of rainbow trout (Oncorhynchus mykiss) larvae, part 1 – Transcriptomics

Exposure to retene, fluoranthene, and their binary mixture causes distinct transcriptomic and apical outcomes in rainbow trout (Oncorhynchus mykiss) yolk sac alevins

P29 Manuka honey downregulates IL-4-induced CCL26 via activation of the aryl hydrocarbon receptor

Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) – A comparison with lysosomotropic drugs

Tn P and AHR-CYP1A1 Signaling Crosstalk in an Injury-Induced Zebrafish Inflammation Model

PBTK modeled perfluoroalkyl acid kinetics in zebrafish eleutheroembryos suggests impacts on bioconcentrations by chorion porosity dynamics

Endogenous AhR agonist FICZ accumulates in rainbow trout (Oncorhynchus mykiss) alevins exposed to a mixture of two PAHs, retene and fluoranthene

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