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Replication stress induces POLQ-mediated structural variant formation throughout common fragile sites after entry into mitosis

Nature communications, 2024-11, Vol.15 (1), p.9582-19, Article 9582

2024

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Large transcription units unify copy number variants and common fragile sites arising under replication stress

Genome research, 2015-02, Vol.25 (2), p.189-200

2015

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Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay

Nucleic acids research, 2021-07, Vol.49 (13), p.7507-7524

2021

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Replication stress and mechanisms of CNV formation

Current opinion in genetics & development, 2012-06, Vol.22 (3), p.204-210

2012

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De novo CNV formation in mouse embryonic stem cells occurs in the absence of Xrcc4-dependent nonhomologous end joining

PLoS genetics, 2012-09, Vol.8 (9), p.e1002981

2012

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Use of Bru-Seq and BruChase-Seq for genome-wide assessment of the synthesis and stability of RNA

Methods (San Diego, Calif.), 2014-05, Vol.67 (1), p.45-54

2014

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Cotranscriptional splicing efficiencies differ within genes and between cell types

RNA (Cambridge), 2021-07, Vol.27 (7), p.829-840

2021

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Hydroxyurea induces de novo copy number variants in human cells

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.17360-17365

2011

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Fragile sites in cancer: more than meets the eye

Nature reviews. Cancer, 2017-08, Vol.17 (8), p.489-501

2017

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Phonon interference in crystalline and amorphous confined nanoscopic films

Journal of applied physics, 2017-02, Vol.121 (7)

2017

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Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (6), p.2240-2245

2013

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Pooled segregant sequencing reveals genetic determinants of yeast pseudohyphal growth

PLoS genetics, 2014-08, Vol.10 (8), p.e1004570-e1004570

2014

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Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae

Genetics (Austin), 2008-03, Vol.178 (3), p.1237-1249

2008

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R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

Nature immunology, 2003-05, Vol.4 (5), p.442-451

2003

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Nonhomologous end joining in yeast

Annual review of genetics, 2005-01, Vol.39 (1), p.431-451

2005

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Release from Myosin V via Regulated Recruitment of an E3 Ubiquitin Ligase Controls Organelle Localization

Developmental cell, 2014-03, Vol.28 (5), p.520-533

2014

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Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53

Scientific reports, 2017-03, Vol.7 (1), p.43598, Article 43598

2017

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Genome-wide transcriptional effects of the anti-cancer agent camptothecin

PloS one, 2013-10, Vol.8 (10), p.e78190

2013

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Mechanisms of glycosylase induced genomic instability

PloS one, 2017-03, Vol.12 (3), p.e0174041-e0174041

2017

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Yeast Tdp1 and Rad1-Rad10 Function as Redundant Pathways for Repairing Top1 Replicative Damage

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (21), p.13669-13674

2002

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Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity

PLoS genetics, 2013-06, Vol.9 (6), p.e1003599

2013

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Breaking News on Fragile Sites in Cancer

Cancer cell, 2013-02, Vol.23 (2), p.137-139

2013

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Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

Genome research, 2014-06, Vol.24 (6), p.896-905

2014

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Identification of Suppressor of Clathrin Deficiency-1 ( SCD1 ) and Its Connection to Clathrin-Mediated Endocytosis in Saccharomyces cerevisiae

G3 : genes - genomes - genetics, 2019-03, Vol.9 (3), p.867-877

2019

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Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (19), p.9481-9490

2019

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Replication stress induces POLQ-mediated structural variant formation throughout common fragile sites after entry into mitosis

Large transcription units unify copy number variants and common fragile sites arising under replication stress

Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay

Replication stress and mechanisms of CNV formation

De novo CNV formation in mouse embryonic stem cells occurs in the absence of Xrcc4-dependent nonhomologous end joining

Use of Bru-Seq and BruChase-Seq for genome-wide assessment of the synthesis and stability of RNA

Cotranscriptional splicing efficiencies differ within genes and between cell types

Hydroxyurea induces de novo copy number variants in human cells

Fragile sites in cancer: more than meets the eye

Phonon interference in crystalline and amorphous confined nanoscopic films

Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response

Pooled segregant sequencing reveals genetic determinants of yeast pseudohyphal growth

Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

Nonhomologous end joining in yeast

Release from Myosin V via Regulated Recruitment of an E3 Ubiquitin Ligase Controls Organelle Localization

Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53

Genome-wide transcriptional effects of the anti-cancer agent camptothecin

Mechanisms of glycosylase induced genomic instability

Yeast Tdp1 and Rad1-Rad10 Function as Redundant Pathways for Repairing Top1 Replicative Damage

Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity

Breaking News on Fragile Sites in Cancer

Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

Identification of Suppressor of Clathrin Deficiency-1 ( SCD1 ) and Its Connection to Clathrin-Mediated Endocytosis in Saccharomyces cerevisiae

Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast

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