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Drugging the Cancers Addicted to DNA Repair

JNCI : Journal of the National Cancer Institute, 2017-11, Vol.109 (11)

2017

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DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response

Nature communications, 2019-06, Vol.10 (1), p.2849-8, Article 2849

2019

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Apes in the Anthropocene: flexibility and survival

Trends in ecology & evolution (Amsterdam), 2015-04, Vol.30 (4), p.215-222

2015

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Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (2), p.540-545

2011

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Catastrophic Decline of World's Largest Primate: 80% Loss of Grauer's Gorilla (Gorilla beringei graueri) Population Justifies Critically Endangered Status

PloS one, 2016-10, Vol.11 (10), p.e0162697-e0162697

2016

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EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair

PLoS genetics, 2015-12, Vol.11 (12), p.e1005675

2015

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Cellular Responses to Widespread DNA Replication Stress

International journal of molecular sciences, 2023-12, Vol.24 (23), p.16903

2023

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TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells

Nucleic acids research, 2023-12, Vol.51 (22), p.12224

2023

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A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease

PloS one, 2021-07, Vol.16 (7), p.e0252805-e0252805

2021

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The Critically Endangered western chimpanzee declines by 80

American journal of primatology, 2017-09, Vol.79 (9), p.n/a

2017

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Great apes and biodiversity offset projects in Africa: the case for national offset strategies

PloS one, 2014-11, Vol.9 (11), p.e111671-e111671

2014

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The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow

Nature communications, 2018-06, Vol.9 (1), p.2377-12, Article 2377

2018

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PARP1 is required for chromosomal translocations

Blood, 2013-05, Vol.121 (21), p.4359-4365

2013

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Impact of the COVID-19 Pandemic on Primate Research and Conservation

Animals (Basel), 2022-05, Vol.12 (9), p.1214

2022

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Impact and Lessons Learned from A Half-Century of Primate Conservation Action Planning

Diversity (Basel), 2022-09, Vol.14 (9), p.751

2022

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BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1

iScience, 2022-12, Vol.25 (12), p.105626-105626, Article 105626

2022

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Mountain Gorilla Tug-of-War: Silverbacks Have Limited Control over Reproduction in Multimale Groups

Proceedings of the National Academy of Sciences - PNAS, 2005-06, Vol.102 (26), p.9418-9423

2005

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FOXA1: Growth inhibitor and a favorable prognostic factor in human breast cancer

International journal of cancer, 2007-03, Vol.120 (5), p.1013-1022

2007

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The SET Domain Protein Metnase Mediates Foreign DNA Integration and Links Integration to Nonhomologous End-Joining Repair

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (50), p.18075-18080

2005

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Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells

PloS one, 2009-04, Vol.4 (4), p.e5323-e5323

2009

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Resistance to the BCL-XL degrader DT2216 in T-cell acute lymphoblastic leukemia is rare and correlates with decreased BCL-XL proteolysis

Cancer chemotherapy and pharmacology, 2023-01, Vol.91 (1), p.89-95

2023

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MiR-223-3p promotes genomic stability of hematopoietic progenitors after radiation

Experimental hematology, 2024-01, Vol.129, p.104123, Article 104123

2024

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MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (35), p.17438-17443

2019

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Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition

Cancer chemotherapy and pharmacology, 2017-10, Vol.80 (4), p.861-867

2017

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The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair

The Journal of biological chemistry, 2020-06, Vol.295 (24), p.8186-8194

2020

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Drugging the Cancers Addicted to DNA Repair

DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response

Apes in the Anthropocene: flexibility and survival

Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

Catastrophic Decline of World's Largest Primate: 80% Loss of Grauer's Gorilla (Gorilla beringei graueri) Population Justifies Critically Endangered Status

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair

Cellular Responses to Widespread DNA Replication Stress

TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells

A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease

The Critically Endangered western chimpanzee declines by 80

Great apes and biodiversity offset projects in Africa: the case for national offset strategies

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow

PARP1 is required for chromosomal translocations

Impact of the COVID-19 Pandemic on Primate Research and Conservation

Impact and Lessons Learned from A Half-Century of Primate Conservation Action Planning

BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1

Mountain Gorilla Tug-of-War: Silverbacks Have Limited Control over Reproduction in Multimale Groups

FOXA1: Growth inhibitor and a favorable prognostic factor in human breast cancer

The SET Domain Protein Metnase Mediates Foreign DNA Integration and Links Integration to Nonhomologous End-Joining Repair

Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells

Resistance to the BCL-XL degrader DT2216 in T-cell acute lymphoblastic leukemia is rare and correlates with decreased BCL-XL proteolysis

MiR-223-3p promotes genomic stability of hematopoietic progenitors after radiation

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition

The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair

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