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Neonatal Suckling, Oxytocin, and Early Infant Attachment to the Mother

Frontiers in endocrinology (Lausanne), 2021-02, Vol.11, p.612651-612651

2021

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Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

Journal of Virology, 2010-08, Vol.84 (15), p.7625-7633

2010

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Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV‑1 Protease Inhibitors

ACS medicinal chemistry letters, 2017-12, Vol.8 (12), p.1292-1297

2017

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Discovery and Evaluation of Potent P1 Aryl Heterocycle-Based Thrombin Inhibitors

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.2995-3008

2004

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Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (3), p.444-450

2015

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Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6754-6757

2010

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Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (10), p.2748-2752

2006

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Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Journal of medicinal chemistry, 1998-06, Vol.41 (12), p.2146-2163

1998

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Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5595-5599

2007

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Studies on tumor promoters. 8. The synthesis of phorbol

Journal of the American Chemical Society, 1989-11, Vol.111 (24), p.8957-8958

1989

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Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5- a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry letters, 2008-01, Vol.18 (2), p.721-725

2008

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Studies on tumor promoters. 7. The synthesis of a potentially general precursor of the tiglianes, daphnanes, and ingenanes

Journal of the American Chemical Society, 1989-11, Vol.111 (24), p.8954-8957

1989

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Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (20), p.4411-4416

2005

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Purification of untagged HIV-1 reverse transcriptase by affinity chromatography

Protein expression and purification, 2010-06, Vol.71 (2), p.231-239

2010

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Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (5), p.1536-1540

2011

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Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability

Bioorganic & medicinal chemistry, 2006-10, Vol.14 (20), p.6900-6916

2006

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Endoscopic management of biliary strictures after liver transplantation

World journal of gastroenterology : WJG, 2009-08, Vol.15 (30), p.3725-3733

2009

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9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2282-2293

2005

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Use of N-Fmoc amino acid chlorides and activated 2-(fluorenylmethoxy)-5(4H)-oxazolones in solid-phase peptide synthesis. Efficient syntheses of highly N-alkylated cyclic hexapeptide oxytocin antagonists related to L-365,209

Journal of organic chemistry, 1992-07, Vol.57 (16), p.4394-4400

1992

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A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors

European journal of pharmacology, 2002-08, Vol.450 (1), p.19-28

2002

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Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4161-4164

2004

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A New Class of Simplified Phorbol Ester Analogues: Synthesis and Binding to PKC and ηPKC-C1B (ηPKC-CRD2)

Organic letters, 1999-10, Vol.1 (7), p.1009-1012

1999

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1-(((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo[2.2.1]heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperazine (L-368,899): An Orally Bioavailable, Non-Peptide Oxytocin Antagonist with Potential Utility for Managing Preterm Labor

Journal of medicinal chemistry, 1994-03, Vol.37 (5), p.565-571

1994

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1 – 25 von 6.625

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Neonatal Suckling, Oxytocin, and Early Infant Attachment to the Mother

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV‑1 Protease Inhibitors

Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group

Discovery and Evaluation of Potent P1 Aryl Heterocycle-Based Thrombin Inhibitors

Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant

Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold

Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors

Studies on tumor promoters. 8. The synthesis of phorbol

Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5- a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors

Studies on tumor promoters. 7. The synthesis of a potentially general precursor of the tiglianes, daphnanes, and ingenanes

10-Hydroxy-7,8-dihydropyrazino[1′,2′:1,5]pyrrolo[2,3- d]pyridazine-1,9(2 H,6 H)-diones: Potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants

Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization

Purification of untagged HIV-1 reverse transcriptase by affinity chromatography

Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors

Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability

Endoscopic management of biliary strictures after liver transplantation

9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors

Use of N-Fmoc amino acid chlorides and activated 2-(fluorenylmethoxy)-5(4H)-oxazolones in solid-phase peptide synthesis. Efficient syntheses of highly N-alkylated cyclic hexapeptide oxytocin antagonists related to L-365,209

A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors

Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability

A New Class of Simplified Phorbol Ester Analogues: Synthesis and Binding to PKC and ηPKC-C1B (ηPKC-CRD2)

1-(((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo[2.2.1]heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperazine (L-368,899): An Orally Bioavailable, Non-Peptide Oxytocin Antagonist with Potential Utility for Managing Preterm Labor

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