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A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

Parasites & vectors, 2019-06, Vol.12 (1), p.304-304, Article 304

2019

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To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

International journal of molecular sciences, 2023-04, Vol.24 (7), p.6817

2023

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Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

PLoS neglected tropical diseases, 2020-07, Vol.14 (7), p.e0008447

2020

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Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.511-523

2020

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Synthesis and in vitro evaluation of new benzothiazole derivatives as schistosomicidal agents

Molecules (Basel, Switzerland), 2007-03, Vol.12 (3), p.622-633

2007

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Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

International journal for parasitology -- drugs and drug resistance, 2019-04, Vol.9, p.35-43

2019

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Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside Phosphonates Assessed by Schistosome Worm Killing In Vitro

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5284-5287

2009

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Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model

Experimental parasitology, 2022-07, Vol.238, p.108260-108260, Article 108260

2022

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Therapeutic efficacy of candidate antischistosomal drugs in a murine model of schistosomiasis mansoni

Parasitology research (1987), 2024-05, Vol.123 (5), p.215-215, Article 215

2024

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Activity of 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine against Schistosomiasis mansoni in Mice

Antimicrobial Agents and Chemotherapy, 2003-12, Vol.47 (12), p.3853-3858

2003

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Ailanthus excelsa leaf extract: Chemical characterization, antischistosomal activity, and in silico study of isolated phenolic compounds as promising thioredoxin glutathione reductase inhibitors

Journal of applied pharmaceutical science, 2023

2023

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MCR Synthesis of Praziquantel Derivatives

Chemical biology & drug design, 2012-04, Vol.79 (4), p.470-477

2012

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A parasitological investigation of the effects Diospyros kaki leaves against Schistosoma mansoni in vivo

Egyptian Journal of Chemistry, 2024-12

2024

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Itraconazole, a cytochrome P450 inhibitor, enhanced the efficacy of praziquantel against Schistosoma mansoni infection and alleviated liver injury in mice

Experimental parasitology, 2022-08, Vol.239, p.108293-108293, Article 108293

2022

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To Target or Not to Target ISchistosoma mansoni/I Cyclic Nucleotide Phosphodiesterase 4A?

International journal of molecular sciences, 2023-04, Vol.24 (7)

2023

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Experimental in vivo assessment of immunomodulatory effect of Kalobin (Pelargonium reinforme/sidoides extract) on schistosomiasis mansoni

Parasitologists United journal, 2022-04, Vol.15 (1), p.71-85

2022

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The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo

Experimental parasitology, 2020-01, Vol.208, p.107793-107793, Article 107793

2020

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In Vivo Assessment of the Antischistosomal Activity of OPUNTIA FICUS-INDICA Flowers and Their Chemical Constituents

Egyptian Journal of Chemistry, 2021-08, Vol.64 (8), p.4557-4568

2021

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Further assessment of Mirazid as antischistosomal drug in experimental schistosomiasis hematobium

Pharmaceutical biology, 2010-07, Vol.48 (7), p.775-779

2010

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Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers

The American journal of tropical medicine and hygiene, 1999-06, Vol.60 (6), p.932-935

1999

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Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca 2+-uptake as possible in vitro correlates to in vivo ED 50 determination

International journal for parasitology, 2004, Vol.34 (8), p.971-977

2004

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Effect of praziquantel on the immature stages of Schistosoma haematobium

International journal for parasitology, 2005-11, Vol.35 (13), p.1453-1457

2005

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Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca2+-uptake as possible in vitro correlates to in vivo ED50 determination

International journal for parasitology, 2004-07, Vol.34 (8), p.971-977

2004

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Neocryptolepine analogues containing N-substituted side-chains at C-11: synthesis and antischistosomicidal activity

Medicinal chemistry research, 2012-12, Vol.21 (12), p.4219-4229

2012

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Lack of evidence for an antischistosomal activity of myrrh in experimental animals

The American journal of tropical medicine and hygiene, 2004-08, Vol.71 (2), p.206-210

2004

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A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools

Synthesis and in vitro evaluation of new benzothiazole derivatives as schistosomicidal agents

Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside Phosphonates Assessed by Schistosome Worm Killing In Vitro

Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model

Therapeutic efficacy of candidate antischistosomal drugs in a murine model of schistosomiasis mansoni

Activity of 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine against Schistosomiasis mansoni in Mice

Ailanthus excelsa leaf extract: Chemical characterization, antischistosomal activity, and in silico study of isolated phenolic compounds as promising thioredoxin glutathione reductase inhibitors

MCR Synthesis of Praziquantel Derivatives

A parasitological investigation of the effects Diospyros kaki leaves against Schistosoma mansoni in vivo

Itraconazole, a cytochrome P450 inhibitor, enhanced the efficacy of praziquantel against Schistosoma mansoni infection and alleviated liver injury in mice

To Target or Not to Target ISchistosoma mansoni/I Cyclic Nucleotide Phosphodiesterase 4A?

Experimental in vivo assessment of immunomodulatory effect of Kalobin (Pelargonium reinforme/sidoides extract) on schistosomiasis mansoni

The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo

In Vivo Assessment of the Antischistosomal Activity of OPUNTIA FICUS-INDICA Flowers and Their Chemical Constituents

Further assessment of Mirazid as antischistosomal drug in experimental schistosomiasis hematobium

Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers

Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca 2+-uptake as possible in vitro correlates to in vivo ED 50 determination

Effect of praziquantel on the immature stages of Schistosoma haematobium

Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca2+-uptake as possible in vitro correlates to in vivo ED50 determination

Neocryptolepine analogues containing N-substituted side-chains at C-11: synthesis and antischistosomicidal activity

Lack of evidence for an antischistosomal activity of myrrh in experimental animals

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