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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15072-15077

2014

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Dissecting Specificity in the Janus Kinases: The Structures of JAK-Specific Inhibitors Complexed to the JAK1 and JAK2 Protein Tyrosine Kinase Domains

Journal of molecular biology, 2009-03, Vol.387 (1), p.219-232

2009

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The JAK kinases: Not just another kinase drug discovery target

Seminars in cell & developmental biology, 2008-08, Vol.19 (4), p.319-328

Wilks, Andrew F.

2008

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Plasmodium kinases as targets for new-generation antimalarials

Future medicinal chemistry, 2012-12, Vol.4 (18), p.2295-2310

2012

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The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

Blood, 2006-01, Vol.107 (1), p.176-183

2006

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HIV-Specific Functional Antibody Responses in Breast Milk Mirror Those in Plasma and Are Primarily Mediated by IgG Antibodies

Journal of Virology, 2011-09, Vol.85 (18), p.9555-9567

2011

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Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

Journal of leukocyte biology, 2009-02, Vol.85 (2), p.278-288

2009

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UK's Alleged Use Of Cyprus Bases To Arm Israel and Hit Yemen Draw Protests

The Washington report on Middle East affairs, 2024-03, Vol.43 (2), p.OV-14

Wilks, Andrew

2024

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Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors

ACS medicinal chemistry letters, 2017-12, Vol.8 (12), p.1298-1303

2017

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Origin and Evolution of HIV-1 in Breast Milk Determined by Single-Genome Amplification and Sequencing

Journal of Virology, 2011-03, Vol.85 (6), p.2751-2763

2011

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Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys

The Journal of immunology (1950), 2010-12, Vol.185 (11), p.7097-7106

2010

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The Use of JAK-specific inhibitors as chemical biology tools

Methods in molecular biology (Clifton, N.J.), 2013, Vol.967, p.99

2013

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Lack of B Cell Dysfunction Is Associated with Functional, gp120-Dominant Antibody Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

Journal of Virology, 2013-10, Vol.87 (20), p.11121-11134

2013

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c-FMS inhibitors: a patent review

Expert opinion on therapeutic patents, 2011-02, Vol.21 (2), p.147-165

2011

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The 2.7 Å Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain

Journal of molecular biology, 2007-03, Vol.367 (3), p.839-847

2007

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Limited Contribution of Mucosal IgA to Simian Immunodeficiency Virus (SIV)-Specific Neutralizing Antibody Response and Virus Envelope Evolution in Breast Milk of SIV-Infected, Lactating Rhesus Monkeys

Journal of Virology, 2010-08, Vol.84 (16), p.8209-8218

2010

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Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5887-5892

2009

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Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia

Oncotarget, 2017-08, Vol.8 (35), p.57948-57963

2017

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Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys

Journal of Virology, 2013-10, Vol.87 (20), p.11292-11299

2013

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High Cell-Free Virus Load and Robust Autologous Humoral Immune Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

Journal of Virology, 2011-09, Vol.85 (18), p.9517-9526

2011

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CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

The FASEB journal, 2006-09, Vol.20 (11), p.1921-1923

2006

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First Case of Foot Drop Associated with Capecitabine in a Patient with Thymidylate Synthase Polymorphism

Curēus (Palo Alto, CA), 2017-01

2017

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Memory CD4+ T Lymphocytes in the Gastrointestinal Tract Are a Major Source of Cell-Associated Simian Immunodeficiency Virus in Chronic Nonpathogenic Infection of African Green Monkeys

Journal of Virology, 2012-10, Vol.86 (20), p.11380-11385

2012

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Vascular Endothelial Growth Factor D (VEGF-D) is a Ligand for the Tyrosine Kinases VEGF Receptor 2 (Flk1) and VEGF Receptor 3 (Flt4)

Proceedings of the National Academy of Sciences - PNAS, 1998-01, Vol.95 (2), p.548-553

1998

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Dissecting Specificity in the Janus Kinases: The Structures of JAK-Specific Inhibitors Complexed to the JAK1 and JAK2 Protein Tyrosine Kinase Domains

The JAK kinases: Not just another kinase drug discovery target

Plasmodium kinases as targets for new-generation antimalarials

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

HIV-Specific Functional Antibody Responses in Breast Milk Mirror Those in Plasma and Are Primarily Mediated by IgG Antibodies

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

UK's Alleged Use Of Cyprus Bases To Arm Israel and Hit Yemen Draw Protests

Mucosal Immunization of Lactating Female Rhesus Monkeys with a Transmitted/Founder HIV-1 Envelope Induces Strong Env-Specific IgA Antibody Responses in Breast Milk

Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors

Origin and Evolution of HIV-1 in Breast Milk Determined by Single-Genome Amplification and Sequencing

Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys

The Use of JAK-specific inhibitors as chemical biology tools

Lack of B Cell Dysfunction Is Associated with Functional, gp120-Dominant Antibody Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

c-FMS inhibitors: a patent review

The 2.7 Å Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain

Limited Contribution of Mucosal IgA to Simian Immunodeficiency Virus (SIV)-Specific Neutralizing Antibody Response and Virus Envelope Evolution in Breast Milk of SIV-Infected, Lactating Rhesus Monkeys

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)

Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia

Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys

High Cell-Free Virus Load and Robust Autologous Humoral Immune Responses in Breast Milk of Simian Immunodeficiency Virus-Infected African Green Monkeys

CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

First Case of Foot Drop Associated with Capecitabine in a Patient with Thymidylate Synthase Polymorphism

Memory CD4+ T Lymphocytes in the Gastrointestinal Tract Are a Major Source of Cell-Associated Simian Immunodeficiency Virus in Chronic Nonpathogenic Infection of African Green Monkeys

Vascular Endothelial Growth Factor D (VEGF-D) is a Ligand for the Tyrosine Kinases VEGF Receptor 2 (Flk1) and VEGF Receptor 3 (Flt4)

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