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Anti-CRISPR proteins function through thermodynamic tuning and allosteric regulation of CRISPR RNA-guided surveillance complex

Nucleic acids research, 2022-10, Vol.50 (19), p.11243-11254

2022

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Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic

Nature communications, 2022-12, Vol.13 (1), p.7762-12, Article 7762

2022

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Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic

Cell reports. Medicine, 2021-06, Vol.2 (6), p.100319-100319, Article 100319

2021

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Antibacterial activity of THAM Trisphenylguanide against methicillin-resistant Staphylococcus aureus

PloS one, 2014-05, Vol.9 (5), p.e97742

2014

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Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System

Molecular pharmaceutics, 2016-03, Vol.13 (3), p.1191-1196

2016

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CRISPR RNA-guided autonomous delivery of Cas9

Nature structural & molecular biology, 2019-01, Vol.26 (1), p.14-24

2019

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Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.E5113-E5121

2017

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Novel guanide-substituted compounds bind to CXCR4 and inhibit breast cancer metastasis

Anti-cancer drugs, 2014-01, Vol.25 (1), p.8-16

2014

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Novel Compounds Containing Multiple Guanide Groups That Bind the HIV Coreceptor CXCR4

Antimicrobial Agents and Chemotherapy, 2011-01, Vol.55 (1), p.255-263

2011

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CRISPR-Cas, Argonaute proteins and the emerging landscape of amplification-free diagnostics

Methods (San Diego, Calif.), 2022-09, Vol.205, p.1-10

2022

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A virally encoded tRNA neutralizes the PARIS antiviral defence system

Nature (London), 2024-10, Vol.634 (8033), p.424-431

2024

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Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays

Nature structural & molecular biology, 2023-11, Vol.30 (11), p.1675-1685

2023

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A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium

Cellular and molecular gastroenterology and hepatology, 2019-01, Vol.8 (1), p.157-171.e3

2019

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Structure of the Fab Fragment of F105, a Broadly Reactive Anti-Human Immunodeficiency Virus (HIV) Antibody That Recognizes the CD4 Binding Site of HIV Type 1 gp120

Journal of Virology, 2005-10, Vol.79 (20), p.13060-13069

2005

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Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events

Cell and tissue research, 2018-02, Vol.371 (2), p.293-307

2018

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Improved guanide compounds which bind the CXCR4 co-receptor and inhibit HIV-1 infection

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.2197-2201

2013

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In Vivo Efficacy of Anti-Glycoprotein 41, But Not Anti-Glycoprotein 120, Immunotoxins in a Mouse Model of HIV Infection

The Journal of immunology (1950), 2003-02, Vol.170 (4), p.2236-2241

2003

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Sphaeric Acid, a New Succinic Acid Derivative from a Sphaeropsis sp

Journal of natural products (Washington, D.C.), 1999-02, Vol.62 (2), p.358-360

1999

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A virally encoded tRNA neutralizes the PARIS antiviral defence system

Nature (London), 2024-10, Vol.634 (8033), p.424-3

2024

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Peptides selected from a phage display library with an HIV-neutralizing antibody elicit antibodies to HIV gp120 in rabbits, but not to the same epitope

AIDS research and human retroviruses, 2007-11, Vol.23 (11), p.1416-1427

2007

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Programmed Self-Assembly of an Active P22-Cas9 Nano Carrier System

Molecular pharmaceutics, 2016-02, Vol.13 (3), p.1191-1196

2016

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A modified SCID mouse model of HIV infection with utility for testing anti-HIV therapies

AIDS research and human retroviruses, 2003-10, Vol.19 (10), p.901-908

2003

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A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric EpitheliumSummary

Cellular and molecular gastroenterology and hepatology, 2019-01, Vol.8 (1), p.157-171.e3

2019

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Antibacterial Activity of THAM Trisphenylguanide against Methicillin-Resistant Staphylococcus aureus: e97742

PloS one, 2014-05, Vol.9 (5)

2014

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Approaches to the Syntheses of 2- and 3-Phosphonomethyl Derivatives of Arabinose Via Pentacovalent Oxaphospholene Methodology

Phosphorus, sulfur, and silicon and the related elements, 1999-01, Vol.144 (1), p.177-180

1999

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Anti-CRISPR proteins function through thermodynamic tuning and allosteric regulation of CRISPR RNA-guided surveillance complex

Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic

Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic

Antibacterial activity of THAM Trisphenylguanide against methicillin-resistant Staphylococcus aureus

Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System

CRISPR RNA-guided autonomous delivery of Cas9

Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity

Novel guanide-substituted compounds bind to CXCR4 and inhibit breast cancer metastasis

Novel Compounds Containing Multiple Guanide Groups That Bind the HIV Coreceptor CXCR4

CRISPR-Cas, Argonaute proteins and the emerging landscape of amplification-free diagnostics

A virally encoded tRNA neutralizes the PARIS antiviral defence system

Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays

A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium

Structure of the Fab Fragment of F105, a Broadly Reactive Anti-Human Immunodeficiency Virus (HIV) Antibody That Recognizes the CD4 Binding Site of HIV Type 1 gp120

Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events

Improved guanide compounds which bind the CXCR4 co-receptor and inhibit HIV-1 infection

In Vivo Efficacy of Anti-Glycoprotein 41, But Not Anti-Glycoprotein 120, Immunotoxins in a Mouse Model of HIV Infection

Sphaeric Acid, a New Succinic Acid Derivative from a Sphaeropsis sp

A virally encoded tRNA neutralizes the PARIS antiviral defence system

Peptides selected from a phage display library with an HIV-neutralizing antibody elicit antibodies to HIV gp120 in rabbits, but not to the same epitope

Programmed Self-Assembly of an Active P22-Cas9 Nano Carrier System

A modified SCID mouse model of HIV infection with utility for testing anti-HIV therapies

A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric EpitheliumSummary

Antibacterial Activity of THAM Trisphenylguanide against Methicillin-Resistant Staphylococcus aureus: e97742

Approaches to the Syntheses of 2- and 3-Phosphonomethyl Derivatives of Arabinose Via Pentacovalent Oxaphospholene Methodology

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