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Determining True HER2 Gene Status in Breast Cancers With Polysomy by Using Alternative Chromosome 17 Reference Genes: Implications for Anti-HER2 Targeted Therapy

Journal of clinical oncology, 2011-11, Vol.29 (31), p.4168-4174

2011

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

PloS one, 2024-02, Vol.19 (2), p.e0293548

2024

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Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells

PloS one, 2010-02, Vol.5 (2), p.e9135

2010

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Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice

Aging cell, 2011-06, Vol.10 (3), p.418-428

2011

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Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release

PloS one, 2010-12, Vol.5 (12), p.e15743-e15743

2010

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Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease

Genome medicine, 2021-05, Vol.13 (1), p.76-76, Article 76

2021

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Single‐nucleus RNAseq‐derived pseudo‐temporal modeling of neurodegeneration in astrocytes of older brains

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Pathway modeling applied to TREAT‐AD proteomic targets demonstrates linkages between AD endophenotypes

Alzheimer's & dementia, 2021-12, Vol.17, p.e054829-n/a

2021

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Alternative Theory of AD Pathogenesis: Membrane Delimitation of the Histone Acetyltransferase Tip60/Kat5

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments

The Journal of biological chemistry, 2015-04, Vol.290 (15), p.9511-9520

2015

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Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains

Alzheimer's & dementia : translational research & clinical interventions, 2024-04, Vol.10 (2), p.e12461-n/a

2024

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Optimizing Parkinson’s disease diagnosis: the role of a dual nuclear imaging algorithm

NPJ Parkinson's Disease, 2018-02, Vol.4 (1), p.5-7, Article 5

2018

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Protein‐protein interaction networks reveal paths connecting functional domains associated in Alzheimer’s disease

Alzheimer's & dementia, 2021-12, Vol.17, p.e057673-n/a

2021

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A proteome‐derived temporal model of neurodegeneration in older brains

Alzheimer's & dementia, 2021-12, Vol.17, p.e057845-n/a

2021

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Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling

Molecular and cellular neuroscience, 2016-01, Vol.70, p.1-10

2016

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Proteolytic Processing of the p75 Neurotrophin Receptor and Two Homologs Generates C-Terminal Fragments with Signaling Capability

The Journal of neuroscience, 2003-07, Vol.23 (13), p.5425-5436

2003

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New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop

Alzheimer's & dementia : translational research & clinical interventions, 2024-01, Vol.10 (1), p.e12458-n/a

2024

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Identification of Putative Immunologic Targets for Colon Cancer Prevention Based on Conserved Gene Upregulation from Preinvasive to Malignant Lesions

Cancer prevention research (Philadelphia, Pa.), 2013-07, Vol.6 (7), p.666-674

2013

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Familial Alzheimer's disease mutations inhibit γ‐secretase‐mediated liberation of β‐amyloid precursor protein carboxy‐terminal fragment

Journal of neurochemistry, 2005-09, Vol.94 (5), p.1189-1201

2005

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Fe65 Stimulates Proteolytic Liberation of the β-Amyloid Precursor Protein Intracellular Domain

The Journal of biological chemistry, 2007-11, Vol.282 (46), p.33313-33325

2007

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Polymorphisms in the DNA repair gene XRCC1 and age-related disease

Mechanisms of ageing and development, 2003, Vol.124 (1), p.27-32

2003

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LINGO-1 promotes lysosomal degradation of amyloid-β protein precursor

Pathobiology of aging & age related diseases, 2015-01, Vol.5 (1), p.25796-25796

2015

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Biological Domain Network Analysis Identifies Potential Triadic Interaction between Mitochondria, Nuclear Epigenetics, and Synaptic Viability

Alzheimer's & dementia, 2023-12, Vol.19 (S11), p.n/a

2023

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Biological Domain Network Analysis Identifies Potential Triadic Interaction between Mitochondria, Nuclear Epigenetics, and Synaptic Viability

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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AD Biological Domains—an evolving computational resource for big data classification in AD from the TREAT‐AD Consortium

Alzheimer's & dementia, 2023-12, Vol.19 (S12), p.n/a

2023

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Determining True HER2 Gene Status in Breast Cancers With Polysomy by Using Alternative Chromosome 17 Reference Genes: Implications for Anti-HER2 Targeted Therapy

Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells

Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice

Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release

Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease

Single‐nucleus RNAseq‐derived pseudo‐temporal modeling of neurodegeneration in astrocytes of older brains

Pathway modeling applied to TREAT‐AD proteomic targets demonstrates linkages between AD endophenotypes

Alternative Theory of AD Pathogenesis: Membrane Delimitation of the Histone Acetyltransferase Tip60/Kat5

LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments

Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains

Optimizing Parkinson’s disease diagnosis: the role of a dual nuclear imaging algorithm

Protein‐protein interaction networks reveal paths connecting functional domains associated in Alzheimer’s disease

A proteome‐derived temporal model of neurodegeneration in older brains

Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling

Proteolytic Processing of the p75 Neurotrophin Receptor and Two Homologs Generates C-Terminal Fragments with Signaling Capability

New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop

Identification of Putative Immunologic Targets for Colon Cancer Prevention Based on Conserved Gene Upregulation from Preinvasive to Malignant Lesions

Familial Alzheimer's disease mutations inhibit γ‐secretase‐mediated liberation of β‐amyloid precursor protein carboxy‐terminal fragment

Fe65 Stimulates Proteolytic Liberation of the β-Amyloid Precursor Protein Intracellular Domain

Polymorphisms in the DNA repair gene XRCC1 and age-related disease

LINGO-1 promotes lysosomal degradation of amyloid-β protein precursor

Biological Domain Network Analysis Identifies Potential Triadic Interaction between Mitochondria, Nuclear Epigenetics, and Synaptic Viability

Biological Domain Network Analysis Identifies Potential Triadic Interaction between Mitochondria, Nuclear Epigenetics, and Synaptic Viability

AD Biological Domains—an evolving computational resource for big data classification in AD from the TREAT‐AD Consortium

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