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Disease‐Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.900-915

2018

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Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology

European journal of pediatrics, 2020-05, Vol.179 (5), p.839-847

2020

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Innovative approaches and recent advances in the study of ontogeny of drug metabolism and transport

British journal of clinical pharmacology, 2022-10, Vol.88 (10), p.4285-4296

2022

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A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization

Clinical pharmacology and therapeutics, 2019-11, Vol.106 (5), p.1083-1092

2019

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Benefit‐Risk Assessment of Off‐Label Drug Use in Children: The Bravo Framework

Clinical pharmacology and therapeutics, 2021-10, Vol.110 (4), p.952-965

2021

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Innovative methodologies in paediatric drug development: A conect4children (c4c) special issue

British journal of clinical pharmacology, 2022-12, Vol.88 (12), p.4962-4964

2022

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Physiologically‐Based Pharmacokinetic Modeling for Drug Dosing in Pediatric Patients: A Tutorial for a Pragmatic Approach in Clinical Care

Clinical pharmacology and therapeutics, 2023-11, Vol.114 (5), p.960-971

2023

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The use of dipyrone (metamizol) as an analgesic in children: What is the evidence? A review

Pediatric anesthesia, 2017-12, Vol.27 (12), p.1193-1201

2017

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Pharmacokinetics in children with chronic kidney disease

Pediatric nephrology (Berlin, West), 2020-07, Vol.35 (7), p.1153-1172

2020

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Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature

Clinical pharmacokinetics, 2020-02, Vol.59 (2), p.173-205

2020

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Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper

British journal of clinical pharmacology, 2022-12, Vol.88 (12), p.4965-4984

2022

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Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

Journal of clinical pharmacology, 2019-09, Vol.59 (S1), p.S56-S69

2019

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Chloroquine Dosing Recommendations for Pediatric COVID‐19 Supported by Modeling and Simulation

Clinical pharmacology and therapeutics, 2020-08, Vol.108 (2), p.248-252

2020

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Off‐Label, but on‐Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy

Clinical pharmacology and therapeutics, 2022-12, Vol.112 (6), p.1243-1253

2022

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Guiding future paediatric drug studies based on existing pharmacokinetic and efficacy data: Cardiovascular drugs as a proof of concept

British journal of clinical pharmacology, 2023-09, Vol.89 (9), p.2888-2901

2023

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Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling

Archives of toxicology, 2021-09, Vol.95 (9), p.3015-3029

2021

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How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper

British journal of clinical pharmacology, 2022-12, Vol.88 (12), p.5017-5033

2022

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Pharmacokinetic studies in children: recommendations for practice and research

Archives of disease in childhood, 2018-07, Vol.103 (7), p.695-702

2018

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Optimal sedation in pediatric intensive care patients: a systematic review

Intensive care medicine, 2013-09, Vol.39 (9), p.1524-1534

2013

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General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children

British journal of clinical pharmacology, 2022-12, Vol.88 (12), p.4985-4996

2022

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The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.140-149

2021

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Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers

Acta dermato-venereologica, 2023-08, Vol.103, p.adv5286-adv5286

2023

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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Clinical and translational science, 2022-10, Vol.15 (10), p.2392-2402

2022

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Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters

Drug metabolism and disposition, 2014-08, Vol.42 (8), p.1268-1274

2014

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Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

PLoS computational biology, 2019-06, Vol.15 (6), p.e1007117

2019

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Disease‐Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology

Innovative approaches and recent advances in the study of ontogeny of drug metabolism and transport

A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization

Benefit‐Risk Assessment of Off‐Label Drug Use in Children: The Bravo Framework

Innovative methodologies in paediatric drug development: A conect4children (c4c) special issue

Physiologically‐Based Pharmacokinetic Modeling for Drug Dosing in Pediatric Patients: A Tutorial for a Pragmatic Approach in Clinical Care

The use of dipyrone (metamizol) as an analgesic in children: What is the evidence? A review

Pharmacokinetics in children with chronic kidney disease

Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature

Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper

Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

Chloroquine Dosing Recommendations for Pediatric COVID‐19 Supported by Modeling and Simulation

Off‐Label, but on‐Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy

Guiding future paediatric drug studies based on existing pharmacokinetic and efficacy data: Cardiovascular drugs as a proof of concept

Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling

How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper

Pharmacokinetic studies in children: recommendations for practice and research

Optimal sedation in pediatric intensive care patients: a systematic review

General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children

The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters

Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

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