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A preclinical evaluation of niraparib efficacy as monotherapy, maintenance and after olaparib treatment (PARP inhibitor after PARP inhibitor) in patient-derived ovarian xenograft tumor models

European journal of cancer (1990), 2017-02, Vol.72, p.S96-S96

2017

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Identification and characterization of TSR-042, a novel anti-human PD-1 therapeutic antibody

European journal of cancer (1990), 2016-12, Vol.69, p.S102-S102

2016

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Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody

European journal of cancer (1990), 2016-12, Vol.69, p.S102-S102

2016

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Antibacterial agents based on the cyclic d,l -α-peptide architecture

Nature (London), 2001-07, Vol.412 (6845), p.452-455

2001

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458 DNA repair deficiencies in ovarian cancer: Genomic analysis of high grade serous ovarian tumors from the NOVA study

European journal of cancer (1990), 2015-09, Vol.51, p.S97-S98

2015

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506 Phase (Ph) 1/2a study of TSR-011, a potent inhibitor of ALK and TRK, in advanced solid tumors including crizotinib-resistant ALK positive non-small cell lung cancer

European journal of cancer (1990), 2014-11, Vol.50, p.165-165

2014

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716 - A preclinical evaluation of niraparib efficacy as monotherapy, maintenance and after olaparib treatment (PARP inhibitor after PARP inhibitor) in patient-derived ovarian xenograft tumor models

European journal of cancer (1990), 2017-02, Vol.72, p.S96-S96

2017

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391: Highly selective, first-in-class furin inhibitor BOS-318 inhibits ENaC and restores airway hydration in cystic fibrosis

Journal of cystic fibrosis, 2021-11, Vol.20, p.S185

2021

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Coupling of 2-Substituted 1-Fluorovinylstannanes with Organic Halides Catalyzed by Palladium(0)/Copper(I) Iodide. A Mild and Stereospecific Method to Monofluoroolefins

Journal of organic chemistry, 1999-05, Vol.64 (10), p.3476-3482

1999

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310 - Identification and characterization of TSR-042, a novel anti-human PD-1 therapeutic antibody

European journal of cancer (1990), 2016-12, Vol.69, p.S102-S102

2016

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311 - Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody

European journal of cancer (1990), 2016-12, Vol.69, p.S102-S102

2016

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Characterization of 148 Ovarian Cancer tumografts (Avatars) using BROCA-HR deep sequencing

Annals of oncology, 2015-03, Vol.26, p.ii31

2015

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P7.01Characterization of 148 Ovarian Cancer tumografts (Avatars) using BROCA-HR deep sequencing

Annals of oncology, 2015-03, Vol.26 (suppl_2), p.ii31-ii31

2015

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Antiviral cyclic d, l-α-peptides: Targeting a general biochemical pathway in virus infections

Bioorganic & medicinal chemistry, 2005-09, Vol.13 (17), p.5145-5153

2005

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Functional and Mechanistic Analyses of Biomimetic Aminoacyl Transfer Reactions in de Novo Designed Coiled Coil Peptides via Rational Active Site Engineering

Journal of the American Chemical Society, 2007-03, Vol.129 (10), p.2959-2966

2007

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Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a] pyrimidine (NBI 30775/r121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4787-4798

2004

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Synthesis of fluorinated olefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes

Tetrahedron letters, 1999-01, Vol.40 (5), p.827-830

1999

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An Improved Synthesis of Selectively Protected l-Dopa Derivatives from l-Tyrosine

Journal of organic chemistry, 2000-04, Vol.65 (8), p.2574-2576

2000

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Synthesis of 3-phenylpyrazolo[4,3- b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-Releasing factor receptor type-1 antagonists

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (19), p.3367-3370

2003

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Initial Structure–Activity Relationship Studies of a Novel Series of Pyrrolo[1,2- a]pyrimid-7-ones as GnRH Receptor Antagonists

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (3), p.399-402

2002

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Palladium/Copper (I) halide-cocatalyzed stereospecific coupling of 1-fluorovinylstannanes with aryl iodides and acyl chlorides

Tetrahedron letters, 1997-11, Vol.38 (44), p.7677-7680

1997

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New methods for the synthesis of fluoroolefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes and organostannanes

Journal of fluorine chemistry, 2000-02, Vol.101 (2), p.285-290

2000

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Design and synthesis of 3-(2-pyridyl)pyrazolo[1,5-a]pyrimidines as potent CRF1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (15), p.3943-3947

2004

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Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent and Orally Active Corticotropin-Releasing Factor Receptor Antagonists

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4787-4798

2004

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Quinoline-Carboxylic acids are potent inhibitors that inhibit the binding of insulin-Like growth factor (IGF) to IGF-Binding proteins

Bioorganic & medicinal chemistry letters, 2003-06, Vol.13 (11), p.1931-1934

2003

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A preclinical evaluation of niraparib efficacy as monotherapy, maintenance and after olaparib treatment (PARP inhibitor after PARP inhibitor) in patient-derived ovarian xenograft tumor models

Identification and characterization of TSR-042, a novel anti-human PD-1 therapeutic antibody

Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody

Antibacterial agents based on the cyclic d,l -α-peptide architecture

458 DNA repair deficiencies in ovarian cancer: Genomic analysis of high grade serous ovarian tumors from the NOVA study

506 Phase (Ph) 1/2a study of TSR-011, a potent inhibitor of ALK and TRK, in advanced solid tumors including crizotinib-resistant ALK positive non-small cell lung cancer

716 - A preclinical evaluation of niraparib efficacy as monotherapy, maintenance and after olaparib treatment (PARP inhibitor after PARP inhibitor) in patient-derived ovarian xenograft tumor models

391: Highly selective, first-in-class furin inhibitor BOS-318 inhibits ENaC and restores airway hydration in cystic fibrosis

Coupling of 2-Substituted 1-Fluorovinylstannanes with Organic Halides Catalyzed by Palladium(0)/Copper(I) Iodide. A Mild and Stereospecific Method to Monofluoroolefins

310 - Identification and characterization of TSR-042, a novel anti-human PD-1 therapeutic antibody

311 - Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody

Characterization of 148 Ovarian Cancer tumografts (Avatars) using BROCA-HR deep sequencing

P7.01Characterization of 148 Ovarian Cancer tumografts (Avatars) using BROCA-HR deep sequencing

Antiviral cyclic d, l-α-peptides: Targeting a general biochemical pathway in virus infections

Functional and Mechanistic Analyses of Biomimetic Aminoacyl Transfer Reactions in de Novo Designed Coiled Coil Peptides via Rational Active Site Engineering

Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a] pyrimidine (NBI 30775/r121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists

Synthesis of fluorinated olefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes

An Improved Synthesis of Selectively Protected l-Dopa Derivatives from l-Tyrosine

Synthesis of 3-phenylpyrazolo[4,3- b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-Releasing factor receptor type-1 antagonists

Initial Structure–Activity Relationship Studies of a Novel Series of Pyrrolo[1,2- a]pyrimid-7-ones as GnRH Receptor Antagonists

Palladium/Copper (I) halide-cocatalyzed stereospecific coupling of 1-fluorovinylstannanes with aryl iodides and acyl chlorides

New methods for the synthesis of fluoroolefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes and organostannanes

Design and synthesis of 3-(2-pyridyl)pyrazolo[1,5-a]pyrimidines as potent CRF1 receptor antagonists

Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent and Orally Active Corticotropin-Releasing Factor Receptor Antagonists

Quinoline-Carboxylic acids are potent inhibitors that inhibit the binding of insulin-Like growth factor (IGF) to IGF-Binding proteins

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