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Understanding the Tendency of Amorphous Solid Dispersions to Undergo Amorphous–Amorphous Phase Separation in the Presence of Absorbed Moisture

AAPS PharmSciTech, 2011-12, Vol.12 (4), p.1209-1219

2011

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Toward an Understanding of the Factors Influencing Anhydrate-to-Hydrate Transformation Kinetics in Aqueous Environments

Crystal growth & design, 2008-08, Vol.8 (8), p.2684-2693

2008

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Manipulating Theophylline Monohydrate Formation During High-Shear Wet Granulation Through Improved Understanding of the Role of Pharmaceutical Excipients

Pharmaceutical research, 2008-04, Vol.25 (4), p.923-935

2008

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Determination of hydrate transition temperature using transformation kinetics obtained by Raman spectroscopy

Journal of pharmaceutical and biomedical analysis, 2009-02, Vol.49 (2), p.247-252

2009

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An Investigation into the Influence of Counterion on the Properties of Some Amorphous Organic Salts

Molecular pharmaceutics, 2008-12, Vol.5 (6), p.946-955

2008

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Two C-Methyl Derivatives of [ super(11)C]WAY-100635 - Effects of an Amido a-Methyl Group on Metabolism and Brain 5-HT sub(1A) Receptor Radioligand Behavior in Monkey

Molecular imaging and biology, 2005-05, Vol.7 (3), p.209-219

2005

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3-Phenylpiperidines. Central dopamine-autoreceptor stimulating activity

Journal of medicinal chemistry, 1981-12, Vol.24 (12), p.1475-1482

1981

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(+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist

Journal of medicinal chemistry, 1987-11, Vol.30 (11), p.2105-2109

1987

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C1-Methylated 5-hydroxy-2-(dipropylamino)tetralins: central dopamine-receptor stimulating activity

Journal of medicinal chemistry, 1984-08, Vol.27 (8), p.1003-1007

1984

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Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties

Journal of medicinal chemistry, 1989-10, Vol.32 (10), p.2273-2276

1989

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substituted (S)-Phenylpiperidines and Rigid Congeners as Preferential Dopamine Autoreceptor Antagonists: Synthesis and Structure-Activity Relationships

Journal of medicinal chemistry, 1994-08, Vol.37 (17), p.2735-2753

1994

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Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists

Journal of medicinal chemistry, 1993-10, Vol.36 (21), p.3188-3196

1993

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8-Hydroxy-2-(dipropylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

Journal of medicinal chemistry, 1981-08, Vol.24 (8), p.921-923

1981

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Novel antipsychotic drugs share high affinity for σ receptors

European journal of pharmacology, 1988-10, Vol.155 (3), p.345-347

1988

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Stability of Artemisinin in Aqueous Environments: Impact on its Cytotoxic Action to Ehrlich Ascites Tumour Cells

Journal of pharmacy and pharmacology, 1997-12, Vol.49 (12), p.1254-1258

1997

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Composition of the Essential Oil from Roots and Rhizomes of Valeriana wallichii DC

Flavour and fragrance journal, 1997-03, Vol.12 (2), p.123-131

1997

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Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[(trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo

Journal of medicinal chemistry, 1993-10, Vol.36 (22), p.3409-3416

1993

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σ-Receptors: Implication for the control of neuronal activity of nigral dopamine-containing neurons

European journal of pharmacology, 1991-08, Vol.201 (2), p.199-202

1991

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Resolved monophenolic 2-aminotetralins and 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines: structural and stereochemical considerations for centrally acting pre- and postsynaptic dopamine-receptor agonists

Journal of medicinal chemistry, 1985-02, Vol.28 (2), p.215-225

1985

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Investigations with GMC2021 in experimental models predictive of antimigraine activity and coronary side-effect potential

European journal of pharmacology, 1996-09, Vol.312 (1), p.53-62

1996

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Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 1. Effects of substituents in the aromatic system on serotonin and dopamine receptor subtypes

Journal of medicinal chemistry, 1995-06, Vol.38 (12), p.2202-2216

1995

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6,7,8,9-Tetrahydro-N,N-di-n-propyl-3H-benzindol-8-amines. Derivatives as Potent and Orally Active Serotonin 5-HT1A Receptor Agonists

Journal of medicinal chemistry, 1994-09, Vol.37 (20), p.3263-3273

1994

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Resolved 3-(3-Hydroxyphenyl)-N-n-propylpiperidine and its analogs: central dopamine receptor activity

Journal of medicinal chemistry, 1984-08, Vol.27 (8), p.1030-1036

1984

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The Essential Oil and Valepotriates from Roots of Valeriana javanica Blume Grown in Indonesia

Flavour and fragrance journal, 1996-09, Vol.11 (5), p.321-326

1996

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Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 2. Effect of 8-amino nitrogen substitution on serotonin receptor binding and pharmacology

Journal of medicinal chemistry, 1995-06, Vol.38 (12), p.2217-2230

1995

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Understanding the Tendency of Amorphous Solid Dispersions to Undergo Amorphous–Amorphous Phase Separation in the Presence of Absorbed Moisture

Toward an Understanding of the Factors Influencing Anhydrate-to-Hydrate Transformation Kinetics in Aqueous Environments

Manipulating Theophylline Monohydrate Formation During High-Shear Wet Granulation Through Improved Understanding of the Role of Pharmaceutical Excipients

Determination of hydrate transition temperature using transformation kinetics obtained by Raman spectroscopy

An Investigation into the Influence of Counterion on the Properties of Some Amorphous Organic Salts

Two C-Methyl Derivatives of [ super(11)C]WAY-100635 - Effects of an Amido a-Methyl Group on Metabolism and Brain 5-HT sub(1A) Receptor Radioligand Behavior in Monkey

3-Phenylpiperidines. Central dopamine-autoreceptor stimulating activity

(+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist

C1-Methylated 5-hydroxy-2-(dipropylamino)tetralins: central dopamine-receptor stimulating activity

Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties

substituted (S)-Phenylpiperidines and Rigid Congeners as Preferential Dopamine Autoreceptor Antagonists: Synthesis and Structure-Activity Relationships

Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists

8-Hydroxy-2-(dipropylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

Novel antipsychotic drugs share high affinity for σ receptors

Stability of Artemisinin in Aqueous Environments: Impact on its Cytotoxic Action to Ehrlich Ascites Tumour Cells

Composition of the Essential Oil from Roots and Rhizomes of Valeriana wallichii DC

Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[(trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo

σ-Receptors: Implication for the control of neuronal activity of nigral dopamine-containing neurons

Resolved monophenolic 2-aminotetralins and 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines: structural and stereochemical considerations for centrally acting pre- and postsynaptic dopamine-receptor agonists

Investigations with GMC2021 in experimental models predictive of antimigraine activity and coronary side-effect potential

Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 1. Effects of substituents in the aromatic system on serotonin and dopamine receptor subtypes

6,7,8,9-Tetrahydro-N,N-di-n-propyl-3H-benzindol-8-amines. Derivatives as Potent and Orally Active Serotonin 5-HT1A Receptor Agonists

Resolved 3-(3-Hydroxyphenyl)-N-n-propylpiperidine and its analogs: central dopamine receptor activity

The Essential Oil and Valepotriates from Roots of Valeriana javanica Blume Grown in Indonesia

Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 2. Effect of 8-amino nitrogen substitution on serotonin receptor binding and pharmacology

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