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DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives

Gut, 2021-03, Vol.70 (3), p.606-617

2021

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p53 isoforms differentially impact on the POLι dependent DNA damage tolerance pathway

Cell death & disease, 2021-10, Vol.12 (10), p.941-14, Article 941

2021

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Canonical and non-canonical functions of p53 isoforms: potentiating the complexity of tumor development and therapy resistance

Cell death & disease, 2024-06, Vol.15 (6), p.412-16

2024

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EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells

Cancers, 2019-08, Vol.11 (8), p.1136

2019

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The Tip of an Iceberg: Replication-Associated Functions of the Tumor Suppressor p53

Cancers, 2018-07, Vol.10 (8), p.250

2018

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Current Understanding of RAD52 Functions: Fundamental and Therapeutic Insights

Cancers, 2020-03, Vol.12 (3), p.705

2020

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Combinations of ATR, Chk1 and Wee1 Inhibitors with Olaparib Are Active in Olaparib Resistant Brca1 Proficient and Deficient Murine Ovarian Cells

Cancers, 2022-04, Vol.14 (7), p.1807

2022

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Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome

Oncogene, 2021-08, Vol.40 (31), p.5026-5037

2021

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Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia

Haematologica (Roma), 2020-01, Vol.105 (1), p.170-181

2020

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Circulating Tumor Cells in Breast Cancer Patients: A Balancing Act between Stemness, EMT Features and DNA Damage Responses

Cancers, 2022-02, Vol.14 (4), p.997

2022

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Simulating Space Conditions Evokes Different DNA Damage Responses in Immature and Mature Cells of the Human Hematopoietic System

International journal of molecular sciences, 2023-09, Vol.24 (18), p.13761

2023

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Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation

Oncogene, 2020-05, Vol.39 (19), p.3952-3964

2020

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Links between DNA double strand break repair and breast cancer: Accumulating evidence from both familial and nonfamilial cases

Cancer letters, 2007-04, Vol.248 (1), p.1-17

2007

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NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks

Nucleic acids research, 2014-06, Vol.42 (10), p.6365-6379

2014

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Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation

Scientific reports, 2018-04, Vol.8 (1), p.6071-13, Article 6071

2018

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Dual PARP and RAD51 Inhibitory Drug Conjugates Show Synergistic and Selective Effects on Breast Cancer Cells

Biomolecules (Basel, Switzerland), 2021-07, Vol.11 (7), p.981

2021

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Multiple biochemical properties of the p53 molecule contribute to activation of polymerase iota-dependent DNA damage tolerance

Nucleic acids research, 2020-12, Vol.48 (21), p.12188-12203

2020

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Regulation of MCP-1 chemokine transcription by p53

Molecular cancer, 2010-04, Vol.9 (1), p.82-82, Article 82

2010

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A Fibrinogen Alpha Fragment Mitigates Chemotherapy-Induced MLL Rearrangements

Frontiers in oncology, 2021-06, Vol.11, p.689063-689063

2021

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Modulation of the poly (ADP-ribose) polymerase inhibitor response and DNA recombination in breast cancer cells by drugs affecting endogenous wild-type p53

Carcinogenesis (New York), 2014-10, Vol.35 (10), p.2273-2282

2014

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Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1

Nature microbiology, 2020-10, Vol.5 (10), p.1247-1261

2020

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DNA Substrate Dependence of p53-Mediated Regulation of Double-Strand Break Repair

Molecular and Cellular Biology, 2002-09, Vol.22 (17), p.6306-6317

2002

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53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients

Cancers, 2020-04, Vol.12 (4), p.930

2020

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Biallelic germline BRCA1 mutations in a patient with early onset breast cancer, mild Fanconi anemia‐like phenotype, and no chromosome fragility

Molecular genetics & genomic medicine, 2019-09, Vol.7 (9), p.e863-n/a

2019

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Ovarian cancer: in search of better marker systems based on DNA repair defects

International Journal of Molecular Sciences, 2013-01, Vol.14 (1), p.640-673

2013

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DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives

p53 isoforms differentially impact on the POLι dependent DNA damage tolerance pathway

Canonical and non-canonical functions of p53 isoforms: potentiating the complexity of tumor development and therapy resistance

EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells

The Tip of an Iceberg: Replication-Associated Functions of the Tumor Suppressor p53

Current Understanding of RAD52 Functions: Fundamental and Therapeutic Insights

Combinations of ATR, Chk1 and Wee1 Inhibitors with Olaparib Are Active in Olaparib Resistant Brca1 Proficient and Deficient Murine Ovarian Cells

Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome

Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia

Circulating Tumor Cells in Breast Cancer Patients: A Balancing Act between Stemness, EMT Features and DNA Damage Responses

Simulating Space Conditions Evokes Different DNA Damage Responses in Immature and Mature Cells of the Human Hematopoietic System

Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation

Links between DNA double strand break repair and breast cancer: Accumulating evidence from both familial and nonfamilial cases

NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks

Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation

Dual PARP and RAD51 Inhibitory Drug Conjugates Show Synergistic and Selective Effects on Breast Cancer Cells

Multiple biochemical properties of the p53 molecule contribute to activation of polymerase iota-dependent DNA damage tolerance

Regulation of MCP-1 chemokine transcription by p53

A Fibrinogen Alpha Fragment Mitigates Chemotherapy-Induced MLL Rearrangements

Modulation of the poly (ADP-ribose) polymerase inhibitor response and DNA recombination in breast cancer cells by drugs affecting endogenous wild-type p53

Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1

DNA Substrate Dependence of p53-Mediated Regulation of Double-Strand Break Repair

53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients

Biallelic germline BRCA1 mutations in a patient with early onset breast cancer, mild Fanconi anemia‐like phenotype, and no chromosome fragility

Ovarian cancer: in search of better marker systems based on DNA repair defects

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