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Glutamate-Based Antidepressants: Preclinical Psychopharmacology

Biological psychiatry (1969), 2013-06, Vol.73 (12), p.1125-1132

2013

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Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets

Cellular & molecular biology letters, 2023-03, Vol.28 (1), p.21-21, Article 21

2023

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Neurochemical changes underlying schizophrenia-related behavior in a modified forced swim test in mice

Pharmacology, biochemistry and behavior, 2018-09, Vol.172, p.50-58

2018

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Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs

Neurochemistry international, 2009, Vol.55 (1), p.85-97

2009

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Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia

Psychopharmacologia, 2012-04, Vol.220 (3), p.481-494

2012

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The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu2/3 receptor agonist, LY379268, is 5-HT1A dependent

Behavioural brain research, 2013-11, Vol.256, p.298-304

2013

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Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist

Pharmacology, biochemistry and behavior, 2005-08, Vol.81 (4), p.901-906

2005

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Prevention of MK-801-induced amnestic effect with combined activation of 5-HT1A and muscarinic receptors in mice

Pharmacology, biochemistry and behavior, 2024-05, Vol.238, p.173749-173749, Article 173749

2024

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Nitric Oxide-Dependent Pathways as Critical Factors in the Consequences and Recovery after Brain Ischemic Hypoxia

Biomolecules (Basel, Switzerland), 2021-07, Vol.11 (8), p.1097

2021

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Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex

Brain research, 2007-12, Vol.1184, p.88-95

2007

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GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and increased reelin proteins in the hippocampus

Brain research, 2010-06, Vol.1334, p.12-24

2010

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Procognitive activity of nitric oxide inhibitors and donors in animal models

Nitric oxide, 2022-02, Vol.119, p.29-40

2022

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Depression and schizophrenia viewed from the perspective of amino acidergic neurotransmission: Antipodes of psychiatric disorders

Pharmacology & therapeutics (Oxford), 2019-01, Vol.193, p.75-82

2019

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Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats

Brain research bulletin, 2003-07, Vol.61 (2), p.159-164

2003

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Regulation of Glutamatergic Activity via Bidirectional Activation of Two Select Receptors as a Novel Approach in Antipsychotic Drug Discovery

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8811

2020

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The Impact of LY487379 or CDPPB on eNOS Expression in the Mouse Brain and the Effect of Joint Administration of Compounds with NO • Releasers on MK-801- or Scopolamine-Driven Cognitive Dysfunction in Mice

Molecules (Basel, Switzerland), 2024-01, Vol.29 (3), p.627

2024

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Prenatal stress aggravates age-dependent cognitive decline, insulin signaling dysfunction, and the pro-inflammatory response in the APPNL-F/NL-F mouse model of Alzheimer's disease

Neurobiology of disease, 2023-08, Vol.184, p.106219-106219, Article 106219

2023

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Serotonergic–Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8612

2021

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Neurochemical changes underlying cognitive impairment in olfactory bulbectomized rats and the impact of the mGlu5-positive allosteric modulator CDPPB

Brain research, 2021-10, Vol.1768, p.147577-147577, Article 147577

2021

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Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment

Pharmacology & therapeutics (Oxford), 2016-01, Vol.157, p.10-27

2016

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The mGlu7 receptor in schizophrenia - An update and future perspectives

Pharmacology, biochemistry and behavior, 2022-07, Vol.218, p.173430-173430, Article 173430

2022

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Activation of Metabotropic Glutamate Receptor (mGlu 2 ) and Muscarinic Receptors (M 1 , M 4 , and M 5 ), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis

Biomolecules (Basel, Switzerland), 2023-06, Vol.13 (7), p.1064

2023

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Reversal of MK-801-Induced Disruptions in Social Interactions and Working Memory with Simultaneous Administration of LY487379 and VU152100 in Mice

International journal of molecular sciences, 2019-06, Vol.20 (11), p.2781

2019

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Nitric Oxide-Dependent Mechanisms Underlying MK-801- or Scopolamine-Induced Memory Dysfunction in Animals: Mechanistic Studies

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12282

2021

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On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039

Psychopharmacologia, 2010-12, Vol.212 (4), p.523-535

2010

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Glutamate-Based Antidepressants: Preclinical Psychopharmacology

Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets

Neurochemical changes underlying schizophrenia-related behavior in a modified forced swim test in mice

Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs

Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia

The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu2/3 receptor agonist, LY379268, is 5-HT1A dependent

Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist

Prevention of MK-801-induced amnestic effect with combined activation of 5-HT1A and muscarinic receptors in mice

Nitric Oxide-Dependent Pathways as Critical Factors in the Consequences and Recovery after Brain Ischemic Hypoxia

Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex

GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and increased reelin proteins in the hippocampus

Procognitive activity of nitric oxide inhibitors and donors in animal models

Depression and schizophrenia viewed from the perspective of amino acidergic neurotransmission: Antipodes of psychiatric disorders

Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats

Regulation of Glutamatergic Activity via Bidirectional Activation of Two Select Receptors as a Novel Approach in Antipsychotic Drug Discovery

The Impact of LY487379 or CDPPB on eNOS Expression in the Mouse Brain and the Effect of Joint Administration of Compounds with NO • Releasers on MK-801- or Scopolamine-Driven Cognitive Dysfunction in Mice

Prenatal stress aggravates age-dependent cognitive decline, insulin signaling dysfunction, and the pro-inflammatory response in the APPNL-F/NL-F mouse model of Alzheimer's disease

Serotonergic–Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms

Neurochemical changes underlying cognitive impairment in olfactory bulbectomized rats and the impact of the mGlu5-positive allosteric modulator CDPPB

Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment

The mGlu7 receptor in schizophrenia - An update and future perspectives

Activation of Metabotropic Glutamate Receptor (mGlu 2 ) and Muscarinic Receptors (M 1 , M 4 , and M 5 ), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis

Reversal of MK-801-Induced Disruptions in Social Interactions and Working Memory with Simultaneous Administration of LY487379 and VU152100 in Mice

Nitric Oxide-Dependent Mechanisms Underlying MK-801- or Scopolamine-Induced Memory Dysfunction in Animals: Mechanistic Studies

On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039

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